A5101612047- Respiratory viral infections research
- Gut microbiota and health
- Molecular Biology Techniques and Applications
- Gene expression and cancer classification
- Respiratory and Cough-Related Research
- Single-cell and spatial transcriptomics
- COVID-19 diagnosis using AI
- Genetically Modified Organisms Research
- Weed Control and Herbicide Applications
- Cancer Genomics and Diagnostics
- Streptococcal Infections and Treatments
- Pesticide and Herbicide Environmental Studies
- SARS-CoV-2 and COVID-19 Research
- Gene Regulatory Network Analysis
- SARS-CoV-2 detection and testing
Tsinghua University
2020-2023
Center for Life Sciences
2020-2021
King Center
2020
Rationale: Alteration of human respiratory microbiota had been observed in coronavirus disease (COVID-19). How the is associated with prognosis COVID-19 unclear. Objectives: To characterize feature and dynamics its associations clinical features patients COVID-19. Methods: We conducted metatranscriptome sequencing on 588 longitudinal oropharyngeal swab specimens collected from 192 (including 39 deceased patients) 95 healthy controls same geographic area. Meanwhile, concentration 27 cytokines...
Abstract Glyphosate‐based herbicides (GBHs) are a group of widely used broad‐spectrum agricultural pesticides. Due to the recalcitrance GBH, it has been found in food and environment as contaminant, posing threat public health. The health risks associated with GBH have indicated by reporting acute toxicity data (an exposure at 0.5% dose), which primarily discuss relation accidental high‐rate exposure. Currently, there is little information regarding environmentally relevant levels. In this...
Spatial transcriptomics technology has revolutionized our understanding of cell types and tissue organization, opening possibilities for researchers to explore transcript distributions at subcellular levels. However, existing methods have limitations in resolution, sensitivity, or speed. To overcome these challenges, we introduce SPRINTseq (Spatially Resolved signal-diluted Next-generation Targeted sequencing), an innovative situ sequencing strategy that combines hybrid block coding...
Background: The pandemic of Coronavirus disease 2019 (COVID-19) is ongoing globally, which a big challenge for public health. Alteration human microbiota had been observed in COVID-19. However, it unknown how the associated with fatality COVID-19.Methods: We conducted metatranscriptome sequencing on 588 longitudinal oropharyngeal swab specimens collected from 192 COVID-19 patients recruited LOTUS clinical trial (Registration number: ChiCTR2000029308) (including 39 deceased patients), and 95...
Abstract The pandemic of Coronavirus disease 2019 (COVID-19) is ongoing globally, which a big challenge for public health. Alteration human microbiota had been observed in COVID-19. However, it unknown how the associated with fatality We conducted metatranscriptome sequencing on 588 longitudinal oropharyngeal swab specimens collected from 192 COVID-19 patients recruited LOTUS clinical trial (Registration number: ChiCTR2000029308) (including 39 deceased patients), and 95 healthy controls same...
Abstract Spatial transcriptomics technology has revolutionized our understanding of cell types and tissue organization, opening new possibilities for researchers to explore transcript distributions at subcellular levels. However, existing methods have limitations in resolution, sensitivity, or speed. To overcome these challenges, we introduce SPRINTseq (Spatially Resolved signal-diluted Next-generation Targeted sequencing), an innovative situ sequencing strategy that combines hybrid block...