A5100610434- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Pulmonary Hypertension Research and Treatments
- Circular RNAs in diseases
- Esophageal Cancer Research and Treatment
- Cardiovascular Function and Risk Factors
- Gastrointestinal motility and disorders
- Cardiovascular Issues in Pregnancy
- Cardiac Imaging and Diagnostics
- Neuroendocrine Tumor Research Advances
- Eosinophilic Esophagitis
- Liver Disease Diagnosis and Treatment
- MRI in cancer diagnosis
- Dysphagia Assessment and Management
- Radiomics and Machine Learning in Medical Imaging
- MicroRNA in disease regulation
- Transcranial Magnetic Stimulation Studies
- Functional Brain Connectivity Studies
- Gastric Cancer Management and Outcomes
- Liver Disease and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- Virus-based gene therapy research
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal disorders and treatments
- Gallbladder and Bile Duct Disorders
Affiliated Hospital of Jining Medical University
2023-2024
Shandong University of Traditional Chinese Medicine
2023-2024
First Hospital of Jilin University
2018-2024
Jilin University
2018-2024
Jining Traditional Chinese Medicine Hospital
2024
University of Electronic Science and Technology of China
2024
Second Affiliated Hospital of Fujian Medical University
2023
Fujian Medical University
2023
Beijing Friendship Hospital
2023
Capital Medical University
2018-2023
Background The transition of right ventricle (RV) from a compensated to decompensated state contributes survival in pulmonary arterial hypertension (PAH). This study investigates the significance atrial (RA) dysfunction on disease progression PAH. Methods Eighty patients with PAH, including 58 hemodynamically RV function (PAH-C) and 22 (PAH-D), were compared 80 age-matched sex-matched normal controls. RA longitudinal strain rate (SR) parameters corresponding reservoir (total ε s SR ),...
Hexokinase-2 (HK2) and Beta2-adrenergic receptor (Beta2AR) are overexpressed in hepatocellular carcinoma (HCC) tissues associated with poor prognosis. However, the synergistic effect of HK2 Beta2AR HCC prognosis is not elucidated. The present study aims to investigate association between expressions tissues, evaluate prognosis.Immunohistochemistry was performed on 155 paraffin embedded samples retrieved from archives pathology department. Corresponding clinical data prognostic were collected...
Background Polymyositis (PM) and dermatomyositis (DM) are common types of idiopathic inflammatory myopathy (IIM), wherein patients prone to adverse cardiovascular events. Purpose To explore the value cardiac magnetic resonance imaging (MRI) for detecting involvement in PM/DM using a T 1 mapping technique. Study Type Prospective observational study. Population In all, 25 free symptoms preserved ventricular systolic function healthy volunteers matched age sex served as controls. Field...
Globus pharyngeus is common and has a low cure rate. Its etiology complex reported to be associated with laryngopharyngeal reflux (LPR). However, some patients globus do not exhibit any symptoms or respond proton pump inhibitors (PPIs) treatments. The purpose of this study was clarify the related risk factors these final objective improving curative effect. Forty two afflicted (G group) 38 without (NG were included in study. According Reflux Symptom Index response PPIs treatments, further...
Intestinal barrier dysfunction is not only the consequence of liver cirrhosis, but also an active participant in development cirrhosis. Previous studies showed that external administration insulin-like growth factor 1 (IGF-1) improved intestinal function However, mechanism IGF-1 on cirrhosis fully elucidated. The present study aims to investigate mechanisms improving via regulating tight junctions intestines. We used carbon tetrachloride induced cirrhotic rats effect claudin-1 and occludin...
This study aims to compare laparoscopic total gastrectomy (LTG) with open (OTG) for treating advanced Siewert type Ⅱ and Ⅲ adenocarcinoma of esophagogastric junction (AEG). The data this included 872 patients AEG who were candidates undergoing from January 2012 December 2017 in Gastrointestinal Surgery Department the First Hospital Jilin University. After screening all patients' data, 722 underwent propensity score match (PSM) out them, 685 selected grouped into LTG group (n = 468) OTG 217)....
Pulmonary hypertension during pregnancy carries high mortality rate. The relatively long-acting, specific pulmonary vasodilator treprostinil has been used to improve survival in these parturients. Slow uptitration is performed most cases, and rapid titration not reported the postpartum period.
Pregnancy-associated immunologic alterations may improve the course of asthma. Severe maternal asthma with an exacerbation impairs fetal growth. Lymphocyte activation was estimated by flow cytometry analysis surface markers in non-pregnant healthy and mild or moderate persistent asthmatic women as well asthmatic, third trimester pregnant women. Compared subjects (n = 12) activated pools within CD4 CD8 T cells were larger number NK increased both 13) (all p < 0.05). No further lymphocyte...
This study aims to investigate the role of transcutaneous neuromodulation (TN) on regulation gastrointestinal hormones and bile acids in patients with functional constipation (FC). Twenty FC were treated TN for four weeks. The effects symptoms evaluated by questionnaires. Plasma levels serotonin (5-HT), motilin, somatostatin, vasoactive intestinal peptide (VIP) measured ELISA 12 individual assayed liquid chromatography tandem mass spectrometry. Results as follows. (1) treatment increased...
Introduction: The current study aimed to construct a circNR4A1 loaded exosome (EXO) nano system for the treatment of oral squamous cell carcinoma (OSCC) and elucidate related regulation mechanism in chemoresistance tumor biology. Methods: Exosomes were isolated from HEK293 cells by ultracentrifugation method. Then, purified nanoproduction was characterized identified transmission electron microscopy, dynamic light scattering, Western blot. hydrophobic then into exosomes coincubation effects...
To study the safety and efficacy of laparoscopic subtotal colectomy (LASC) with cecorectal anastomosis for slow-transit constipation (STC).This was a retrospective review all patients undergoing LASC STC between March 2010 May 2017. The main variables included operative time, blood loss, length postoperative hospital stay, complications, long-term outcomes.In this analysis, 56 were included. There 17 males 39 females aged 34 80 years old. mean time 208 ± 21 min, perioperative loss 116 48 mL....
To identify the most effective laxative for bowel preparation in unsedated colonoscopy.Between April 2019 and 2020, a total of 586 outpatients scheduled colonoscopy at First Hospital Jilin University (Changchun, China) were randomized into one two groups, namely, polyethylene glycol (PEG) group or oral sodium phosphate solution (OSP) group. The cleaning efficiency other relevant clinical parameters compared between groups.Each consisted 293 patients. There no significant differences gender,...
The purpose of our study is to understand the current status depression and medical social support in elderly HIV/AIDS, as well role on depression, so provide a certain reference for reducing occurrence population.A total 115 participants with PLWHA (people living HIV/AIDS) aged 50 years or older were collected Guilin from December 2021 July 2022. Depression assessed using Center Streaming Scale (CES-D) Medical Social Support (MOS-SSS). structural equation model was used examine relationship...
To compare the performance of Clear Cell Likelihood Score (ccLS) v1.0 and v2.0 in diagnosing clear cell renal carcinoma (ccRCC) from small masses (SRM).We retrospectively analyzed clinical data MR images patients with pathologically confirmed solid SRM First Medical Center Chinese PLA General Hospital between January 1, 2018, December 31, 2021, Beijing Friendship Capital University Peking 2019 May 17, 2021. Six abdominal radiologists were trained for use ccLS algorithm scored independently...