- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Parasites and Host Interactions
- Viral Infections and Vectors
- Bacillus and Francisella bacterial research
- Poxvirus research and outbreaks
- Mosquito-borne diseases and control
- Bacteriophages and microbial interactions
- Respiratory viral infections research
- Healthcare Regulation
- Vector-borne infectious diseases
- Insect symbiosis and bacterial influences
- Occupational Health and Burnout
- Virology and Viral Diseases
- Healthcare during COVID-19 Pandemic
- Education during COVID-19 pandemic
- Soil Management and Crop Yield
- RNA and protein synthesis mechanisms
- Income, Poverty, and Inequality
- Dental materials and restorations
- Toxoplasma gondii Research Studies
- Phytase and its Applications
- Business and Management Studies
- Social and Economic Solidarity
- Endodontics and Root Canal Treatments
Federal University of São João del-Rei
2013-2024
Centro Universitário Una
2023
University of Cruz Alta
2022
Universidade Regional de Blumenau
2021
Recombinant multiepitope proteins (RMPs) are a promising alternative for application in diagnostic tests and, given their wide the most diverse diseases, this review article aims to survey use of these antigens diagnosis, as well discuss main points surrounding antigens. RMPs usually consisting linear, immunodominant, and phylogenetically conserved epitopes, has been applied experimental diagnosis various human animal such leishmaniasis, brucellosis, cysticercosis, Chagas disease, hepatitis,...
visceral leishmaniasis (VL) is a critical public health problem in over ninety countries. The control measures adopted Brazil have been insufficient when it comes to preventing the spread of this overlooked disease. In context, precise diagnosis VL dogs and humans could help reduce number cases Distinct studies for used single recombinant proteins serological assays; however, results variable, mainly relation sensitivity antigens. development multiepitope-based be relevant solving such...
Chagas disease remains a neglected that is considered to be public health problem. The early diagnosis of cases important improve the prognosis infected patients and prevent transmission. Serological tests are method choice for diagnosis. However, two serological currently recommended confirm positive cases. In this sense, more sensitive specific need developed overcome these current problems. This study aimed develop new recombinant multiepitope protein disease, hereafter named rTC. rTC was...
The Human Cytomegalovirus (HCMV) has infected more than 90% of the world population and its prevalence can be related to individuals geographical socialeconomic status. Serological tests based on ELISA are pivotal for HCMV diagnosis. Due lack standardization in production/purification antigens from viral preparations, several recombinant proteins or peptides. As an alternative, multiepitope may employed.In this work, we developed a protein (rMEHCMV) diagnosis conserved immunodominant...
Rubella is an infection caused by rubella virus (RV) and generally regarded as a mild childhood disease. The disease continues to be of public health importance mainly because when the acquired during early pregnancy, it often results in fetal abnormalities, which are classified congenital syndrome (CRS). An accurate diagnosis thus pivotal for proper treatment.The aim study was produce recombinant multiepitope protein (rMERUB) rubella, based on conserved immunodominant epitopes glycoprotein...
Schistosomiasis is a neglected tropical parasitic disease caused by trematode worms of the genus schistosoma, which affects approximately 240 million people worldwide. diagnosis can be performed parasitological, molecular, and/or immunological methods, however, development new diagnostic methods still essential to guide policy decisions, monitor trends and assess effectiveness interventions.
ABSTRACT Background Monkeypox is a global public health issue caused by the monkeypox virus (MPXV), belonging to Orthopoxvirus genus. As of October 28 2022, total 77,115 laboratory-confirmed cases and 3,610 probable cases, including 36 deaths, were reported, with 9,070 reported in Brazil, second most affected country. The need develop national technologies for rapid diagnosis emerging diseases mass testing population evident, as observed current SARS-CoV-2 pandemic. With that mind, this...
This study evaluated the impact of using calcium-hydroxide or antioxidant agents on bond strength adhesive restorations to bleached dentin. Forty teeth were prepared and allocated into 8 groups according surface treatment after bleaching (application not calcium hydroxide, 10% sodium ascorbate 5% thiosulphate for 10min), time final restoration (immediate 7-days). Sodium perborate with 20% hydrogen peroxide was applied 3 weeks a developed artificial pulp chamber, replacement every week....
Visceral leishmaniasis (VL) is a zoonotic disease, with dogs being the main reservoir of
Rocky Mountain or Brazilian spotted fever, caused by Ricketsia ricketssi, is a fulminant, seasonal, and neglected disease that occurs in focal points of North America South America. Rapid detection are essential for better prognosis survival rate the infected individual. However, diagnosis still faces challenges as accuracy many available laboratory tests fluctuates. Therefore, this review aimed to identify methods antibody antigen detection, its gaps, evolution over time. A search was...
O estresse é um grande causador da imunossupressão, levando ao aumento ocorrência de doenças infecciosas, manifestação autoimunes o desenvolvimento e progressão neoplasias. A principal causa secreção noradrenalina glicocorticoides na corrente sanguínea. Com constante corpo passa a produzir esses hormônios em escala, fazendo com que próprio organismo relaxe as suas defesas, sendo estes os causadores das alterações ocorridas no sistema imune, sistemas cardiovascular, gastrointestinal...
Communication in the third sector before and during COVID 19 pandemic. strategies on social networks of NGOs Blumenau, Santa Catarina, Brazil
Intensive care unit acquired weakness (ICUAW) is frequent in survivors of critical illness. ICUAW multifactorial clinical condition that associated with loss muscle mass and functionality. The some diseases can be up to 1 kg per day because intense catabolism, which prolong the rehabilitation time these patients by 5 years. purpose this article fight against ICUAW, mainly regarding modifiable factors such as: optimization medical nutritional therapy, better metabolic glycemic control, early...
A COVID-19 é uma infecção altamente contagiosa e rapidamente se tornou pandemia. Um dos desafios enfrentados o diagnóstico, visto que os métodos utilizados possuem limitações, como a dependência de insumos importados. O objetivo desse estudo foi divulgar ações estratégias universidades institutos pesquisa para diagnóstico da no Brasil. Deste modo, realizada busca patentes INPI notícias em sites oficiais período 25 fevereiro 10 maio 2020. Além disso, análise comparativa das iniciativas...
Background: Visceral leishmaniasis (VL) is s critical public health problem in over ninety countries. The control measures adopted Brazil have been insufficient when it comes to preventing the spread of this neglected disease. In context, a precise diagnosis VL dogs and humans could help reduce number cases Distinct studies for used single recombinant proteins serological assays; however, results variable, mainly sensitivity antigens. development multiepitope-based be relevant solving such...