A5101608353- Cancer-related Molecular Pathways
- Lung Cancer Treatments and Mutations
- Cancer Treatment and Pharmacology
- Ferroptosis and cancer prognosis
- Cancer Genomics and Diagnostics
- PI3K/AKT/mTOR signaling in cancer
- HER2/EGFR in Cancer Research
- Peptidase Inhibition and Analysis
- Metastasis and carcinoma case studies
- Cancer Immunotherapy and Biomarkers
- Cancer, Lipids, and Metabolism
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Bone and Joint Diseases
- Neuroinflammation and Neurodegeneration Mechanisms
- Salivary Gland Disorders and Functions
- Gastric Cancer Management and Outcomes
- Complementary and Alternative Medicine Studies
- Lipid metabolism and disorders
- Traditional Chinese Medicine Studies
- Prostate Cancer Treatment and Research
- Advanced Breast Cancer Therapies
- Cancer Cells and Metastasis
- Ubiquitin and proteasome pathways
- Cancer Risks and Factors
- Breast Cancer Treatment Studies
Second Affiliated Hospital of Dalian Medical University
2021-2024
Dalian Medical University
2021-2024
Breast Cancer Research Foundation
2021
Weatherford College
2021
Creative Commons
2021
Shenzhen Second People's Hospital
2021
University of Washington
2019
Shanghai First People's Hospital
2017-2018
Chinese General Hospital College of Nursing and Liberal Arts
2018
Jackson Memorial Hospital
2017
This study aimed to explore the efficacy and potential mechanisms of rechallenge therapy with microtubule-targeting agents (MTAs) in patients HER2-low metastatic breast cancer (MBC). We performed a systematic review investigate treatment concept field MBC utilized series cases identified literature illustrate concept. Here we reported two clinical whose disease progressed after prior MTAs such as docetaxel vincristine. When rechallenged disitamab vedotin ((RC48-antibody-drug conjugate (ADC),...
Abstract Background Accumulating evidences indicate that the signal peptide-CUB-EGF-like domain-containing protein 3 (SCUBE3) plays a key role in development and progression of many human cancers. However, underlying mechanism prognosis value SCUBE3 breast cancer are still unclear. Methods The clinical data 137 patients with who underwent surgical resection Taizhou Hospital Zhejiang Province were retrospectively analyzed. We first conducted comprehensive study on expression pattern using...
<abstract> <sec><title>Background</title><p>Metastasis-Associated in Colon Cancer 1(<italic>MACC1</italic>) is a validated biomarker for metastasis and linked to survival. Although extensive experimental evidence indicates an association between <italic>MACC1</italic> diverse cancers, no pan-cancer analyses have yet been performed this marker, the role of immunology remains unknown.</p> </sec> <sec><title>Material...
Abstract The main purpose of this study was to build a prediction model for patients with contralateral breast cancer (CBC) using competing risks methodology. aim is help clinicians predict the probability CBC in (BC) survivors. We reviewed data from Surveillance, Epidemiology, and End Results database 434,065 BC. Eligible were used quantify association between development multiple characteristics BC risk models. A nomogram also created facilitate clinical visualization analysis. Finally,...
Triple-negative breast cancer (TNBC) is distinguished by early recurrence and metastases, a high proclivity for treatment resistance, lack of targeted medicines, highlighting the importance developing innovative therapeutic techniques. Salvia chinensis Benth (SCH) has been widely studied its anticancer properties in variety cancers. However, significance TNBC rarely discussed. Our study investigated effect SCH on underlying mechanisms. First, we used clonogenic, cell viability, flow...
The Intergroup 0116 study has demonstrated a significant survival benefit for completely resected (R0) gastric cancer patients treated with fluorouracil/leucovorin chemoradiotherapy regimen. However, this regimen is also toxic and less effective in terms of distant disease control. Therefore, more efficacious safer urgently needed.Patients R0 carcinoma received up to two 21-day cycles postoperative adjuvant preradiation postradiation DCF chemotherapy (docetaxel 37.5 mg/m on days 1 8,...
Objective: To investigate the safety and efficacy of Weitan Waifu patch on postsurgical gastroparesis syndrome (PGS) gastrointestinal cancer. Methods: The multi-center, double-blind, randomized controlled trial was conducted with superiority design. Patients PGS cancer diagnosed in 4 AAA hospitals abdominal symptom manifested as cold by Chinese local differentiation were recruited. These patients randomly divided into two groups according to 1∶1 proportion. Placebo or applied control group...
To present a case of sporadic adult-onset leukoencephalopathy with neuroaxonal spheroids and pigmented glia.
Abstract Background: Salvia chinensia Benth (SCH) is an herb that has extensively demonstrated antitumor attributes in multiple tumors. However, there are only marginal reports about the impacts of SCH on TNBC-triple negative breast cancer tumorigenesis. Herein, our current research reported vitro effects as well vivo effect, and fundamental mechanisms TNBC. Methods: In vitro, we measured effect TNBC through clonogenic assay, cell viability, flow cytometry, apoptosis migration invasion...