A5081926231- Innovations in Medical Education
- Obsessive-Compulsive Spectrum Disorders
- Clinical Reasoning and Diagnostic Skills
- Multiple Sclerosis Research Studies
- Peripheral Neuropathies and Disorders
- Empathy and Medical Education
- Genetics and Neurodevelopmental Disorders
- Autism Spectrum Disorder Research
- Neurological disorders and treatments
- Hospital Admissions and Outcomes
- Pharmacological Effects and Toxicity Studies
- Genomics and Rare Diseases
- Botulinum Toxin and Related Neurological Disorders
- Child and Adolescent Health
- Schizophrenia research and treatment
- Attention Deficit Hyperactivity Disorder
- Epilepsy research and treatment
- Mitochondrial Function and Pathology
- Pharmaceutical studies and practices
- Metabolism and Genetic Disorders
- Radiology practices and education
- Health Sciences Research and Education
- Autoimmune Neurological Disorders and Treatments
- Eating Disorders and Behaviors
- Infectious Encephalopathies and Encephalitis
Children's Hospital of Eastern Ontario
2016-2025
University of Ottawa
2015-2024
University of Newcastle Australia
2023
Agricultural Research Institute of Ontario
2022
Novartis (Canada)
2019
University of Toronto
2006-2014
Hospital for Sick Children
2006-2014
Montreal Neurological Institute and Hospital
2014
Imaging Center
2014
McGill University
2014
The incidence of acquired demyelination the CNS (acquired demyelinating syndromes [ADS]) in children is unknown. It important that physicians recognize features ADS to facilitate care and appreciate future risk multiple sclerosis (MS).To determine incidence, clinical features, familial autoimmune history, acute management Canadian with ADS.Incidence case-specific data were obtained through Pediatric Surveillance Program from April 1, 2004, March 31, 2007. Before study initiation, a survey...
<h3>Importance</h3> A significant portion of neurology literature is published in general medicine journals. Despite this, a detailed examination publication patterns articles these journals has not yet been carried out. <h3>Objective</h3> To examine the during 10-year period using bibliometric approach. <h3>Design, Setting, and Participants</h3> This cross-sectional analysis identified top 5 2017 Journal Citations Report. Four other medical subspecialties (ie, immunology, endocrinology,...
To determine the impact of pediatric-onset multiple sclerosis (MS) on age-expected brain growth.Whole and regional volumes 36 patients with relapsing-remitting MS onset prior to 18 years age were segmented in 185 longitudinal MRI scans (2-11 per participant, 3-month 2-year scan intervals). 25 age- sex-matched healthy normal controls (NC) also acquired at baseline 2 later same scanner as group. A total 874 from 339 participants NIH-funded study development intervals used an growth reference....
Abstract Febrile‐infection related epilepsy syndrome (FIRES) is a devastating neurological condition characterized by febrile illness preceding new onset refractory status epilepticus (NORSE). Increasing evidence suggests innate immune dysfunction as potential pathological mechanism. We report an international retrospective cohort of 25 children treated with anakinra, recombinant interleukin‐1 receptor antagonist, immunomodulator for FIRES. Anakinra was potentially safe only one child...
Purpose: The hidden and informal curricula refer to learning in response unarticulated processes constraints, falling outside the formal medical curriculum. curriculum has been identified as requiring attention across all levels of learning. We sought assess knowledge perceptions continuum at a single institution.
Abstract Heterozygous mutations in KMT2B are associated with an early-onset, progressive and often complex dystonia (DYT28). Key characteristics of typical disease include focal motor features at presentation, evolving through a caudocranial pattern into generalized dystonia, prominent oromandibular, laryngeal cervical involvement. Although KMT2B-related is emerging as one the most common causes early-onset genetic much remains to be understood about full spectrum disease. We describe cohort...
Many neurologic manifestations of Epstein-Barr virus (EBV) infection have been documented, including encephalitis, aseptic meningitis, transverse myelitis, and Guillain-Barré syndrome. These can occur alone or coincidentally with the clinical picture infectious mononucleosis. Since 1994, The Hospital for Sick Children has maintained a prospective registry all children admitted acute encephalitis. This report summarizes cases virus-associated encephalitis compiled from 1994 to 2003....
The purpose of this study was to assess YouTube videos for their efficacy as a patient resource infantile spasms. Videos were searched using the terms spasm, epileptic and West syndrome. top 25 under each term selected according set criteria. Technical quality, diagnosis spasms, suitability teaching assessed by 2 neurologists Medical Video Rating Scale. There 5858 found. Of 100 videos, 46% did not meet selection Mean rating technical quality 4.0 5 rater 1 3.9 2. Raters found 60% 64%...
Objectives: We wanted to examine the extent which “neurophobia” exists among medical students and determine if students’ perceptions of neurology differ by year study while exploring factors that contribute development “neurophobia”. Methods: used a two-phase, sequential, mixed-methods explanatory design in this single centre study. Phase 1 involved collection analysis questionnaire administered first three years school. 2 focus groups subgroup who demonstrated evidence neurophobia 1....
Productivity and countries of origin publications within the field medical education research have not been explored. Using bibliometric techniques we conducted an analysis studies evaluating interventions, examining country where originated as well networks authors identified `most productive'. PubMed was used to search for evaluative education. We then examined relative productivity with >100 in our sample (number publications/number schools country). Author from top 2 highest were...
Pediatric residents must become proficient with performing a lumbar puncture (LP) during training. Residents have traditionally acquired LP skills by observing the procedure performed more senior resident or staff physician and then attempting themselves. This process can result in variable procedural skill acquisition trainee discomfort. study assessed changes self-reported anxiety when were provided an opportunity to participate interactive training session practice LPs using simulator.All...
<h3>Importance</h3> The recognition of magnetic resonance imaging (MRI) features associated with distinct causes myelitis in children is essential to guide investigations and support diagnostic categorization. <h3>Objective</h3> To determine the clinical MRI outcomes spinal cord involvement pediatric myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), multiple sclerosis (MS), seronegative monophasic myelitis. <h3>Design, Setting, Participants</h3> In this cohort study,...
Antipsychotic use in children is increasing. The purpose of the present article was to provide guidance clinicians on clinical management extrapyramidal side effects second-generation antipsychotics. Published literature, key informant interviews, and discussions with panel members stakeholder partners were used identify areas preferences format for recommendations. Draft recommendations presented a guideline panel. Members evaluated information gathered from systematic review literature...
Disciplines differ in their authorship and citation practices, thus discipline-specific h-index norms are desirable. Thus the goal of this study was to examine relationship between academic rank field medical education, differences MD's PhD's field. Due absence a formalized registry educators, we sampled available editorial board membership (considered proxy for identifying 'career' educators) establish values. These were determined using Web Science (WoS) Google Scholar (GS), internet...
There are over 150 known human proteins which tethered to the cell surface via glycosylphosphatidylinositol (GPI) anchors. These play a variety of important roles in development, and particularly neurogenesis. Not surprisingly, mutations GPI anchor biosynthesis remodeling pathway cause number developmental disorders. This group conditions has been termed inherited deficiencies (IGDs), subgroup congenital disorders glycosylation; they present with variable phenotypes, often including...
Objective The development of cynicism in medicine, defined as a decline empathy and emotional neutralisation during medical training, is significant concern for educators. We sought to use online student discussion groups provide insight into how medicine perceived, the consequences on trainee potential links between hidden curriculum cynicism. Setting Online analysis topics Premed101 (Canadian) Student Doctor Network (American) forums. Participants 511 posts from seven were analysed using...