A5103116187- Nutrition and Health in Aging
- Frailty in Older Adults
- Cancer Treatment and Pharmacology
- Childhood Cancer Survivors' Quality of Life
- Body Composition Measurement Techniques
- Clinical Nutrition and Gastroenterology
- Colorectal Cancer Treatments and Studies
- Cancer, Hypoxia, and Metabolism
- Cancer therapeutics and mechanisms
- Cancer Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Cancer survivorship and care
- Nutritional Studies and Diet
- Thyroid Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Diet and metabolism studies
- PI3K/AKT/mTOR signaling in cancer
- Vascular Tumors and Angiosarcomas
- HER2/EGFR in Cancer Research
- GDF15 and Related Biomarkers
- Histone Deacetylase Inhibitors Research
- Multiple and Secondary Primary Cancers
- Pharmacological Effects and Toxicity Studies
- Cancer Immunotherapy and Biomarkers
Délégation Paris 5
2014-2024
Université Paris Cité
2015-2024
Hôpital Cochin
2014-2024
Assistance Publique – Hôpitaux de Paris
2015-2024
Sorbonne Paris Cité
2022-2024
Institut Cochin
2024
Inserm
2013-2024
Centre National de la Recherche Scientifique
2024
Cancer Institute (WIA)
2024
Maternité Port Royal
2021
Background and Aims : The aim of this study was to evaluate on 1 day the prevalence malnutrition in different types cancer use nutrition support patients with cancer. Methods A 1‐day survey carried out 154 French hospital wards. Malnutrition defined as a body mass index (BMI) <18.5 <75 years old or <21 ≥75 and/or weight loss >10% since disease onset. Oral food intake measured using visual analog scale. Results Nutrition status collected for 1903 (1109 men 794 women, 59.3 ± 13.2...
Abstract Background : Malnutrition is a critical predictor of toxicity and outcome in patients with cancer may be perceived differently by patients, relatives, physicians. Aims To assess the prevalence malnutrition oncology departments to compare it perceptions nutrition status themselves, their closest attending Materials Methods A 1‐day multicentric cross‐sectional survey on was conducted different using patient‐, relative‐, physician‐specific questionnaires. defined weight loss ≥5% within...
Abstract Background Cancer‐associated weight loss (WL) associates with increased mortality. International consensus suggests that WL is driven by a variable combination of reduced food intake and/or altered metabolism, the latter often represented inflammatory biomarker C‐reactive protein (CRP). We aggregated data from Canadian and European research studies to evaluate associations CRP cancer‐associated (primary endpoint) overall survival (OS, secondary endpoint). Methods The set included...
Knowledge about cancer-related malnutrition and the use of clinical nutrition (CN) in real-world setting are lacking. We investigated diagnosis treatment frequency a multinational survey to identify unmet needs cancer patients' care.
A common method for diagnosing sarcopenia involves estimating the muscle mass by computed tomography (CT) via measurements of cross-sectional area (CSMA) all muscles at third lumbar vertebra (L3) level. Recently, single-muscle psoas major L3 have emerged as a surrogate detection, but its reliability and accuracy remain to be demonstrated.This prospective study involved 29 healthcare establishments recruited patients with metastatic cancers. The correlation between skeletal index (SMI = CSMA...
Portal hypertension, the most important complication with cirrhosis of liver, is a serious disease. Sorafenib, tyrosine kinase inhibitor validated in advanced hepatocellular carcinoma. Because angiogenesis pathological hallmark portal goal our study was to determine effect sorafenib on venous flow and portosystemic collateral circulation patients receiving therapy for Porto-collateral circulations were evaluated using magnetic resonance technique prior therapy, at day 30. All under had...
Neutropenia is the main dose-limiting toxicity occurring in docetaxel treatment. The objective of this study was to identify pharmacodynamic (PD) factors responsible for neutropaenia caused by docetaxel. Data were obtained from 92 patients treated with as a monochemotherapy two different treatment centres. A semiphysiological population pharmacokinetic–pharmacodynamic (PK/PD) model applied describe time course neutrophils and neutropaenic effect plasma concentration assumed inhibit...