A5074350719- Pancreatic and Hepatic Oncology Research
- Ubiquitin and proteasome pathways
- Immune cells in cancer
- Cancer Immunotherapy and Biomarkers
- Advanced Technologies in Various Fields
- Physical Activity and Health
- RNA modifications and cancer
- Inflammatory mediators and NSAID effects
- Glycosylation and Glycoproteins Research
- Free Radicals and Antioxidants
- Cancer, Hypoxia, and Metabolism
- Inflammatory Biomarkers in Disease Prognosis
- Retinoids in leukemia and cellular processes
- Food Security and Health in Diverse Populations
- Signaling Pathways in Disease
- Sports Performance and Training
- Prostate Cancer Treatment and Research
- Obesity, Physical Activity, Diet
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Peptidase Inhibition and Analysis
- Infrared Thermography in Medicine
- MicroRNA in disease regulation
- Antioxidant Activity and Oxidative Stress
- Thermoregulation and physiological responses
- AI and Big Data Applications
Peking Union Medical College Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Central South University
2014-2024
Sun Yat-sen University
2014-2024
Shanghai International Studies University
2024
Sun Yat-sen Memorial Hospital
2024
The First Affiliated Hospital, Sun Yat-sen University
2014
Xiangya Hospital Central South University
2014
Biallelic mutations in PIGK cause GPI biosynthesis defect 22 (GPIBD22), characterized with developmental delay, hypotonia, and cerebellar atrophy. The understanding of the underlying causes is limited due to lack suitable disease models. To address this gap, we generated a mouse model deficits, specifically Purkinje cells (Pcp2-cko) an induced pluripotent stem cell (iPSC) using c.87dupT mutant (KI) found GPIBD22 patients. Pcp2-cko mice demonstrated atrophy, ataxia progressive loss which were...
15-F2t-isoprostane is not only a specific marker of lipid peroxidation but also demonstrated to have potent bioactivities and can exert deleterious effects via activating thromboxane A2 receptor (TxA2r). We already that represents mechanism intestinal ischemia/reperfusion (I/R) injury. But no studies focused on production its biological actions postischemic intestine during I/R. This study was carried investigate whether the endogenous action involved in pathogenesis I/R administration...
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<title>Abstract</title> Background To search for immune cells and related risk genes that affect distant metastasis of colorectal cancer, to construct a prediction model based on certain guide systemic screening synchronous metastasis. Methods Firstly, the acquired from TCGA database were screened by differential analysis, differences in infiltration analyzed TIMER algorithm. Then, association analysis. Next, LASSO regression logistic used build predicting model. Finally, accuracy was...
Abstract The development of physical education and health courses is not only an important element in the current stage college education, but also a crucial measure to enhance students’ fitness health. For this reason, paper based on intelligent data analysis build system research changes fitness. This first analyzes user functional requirements for analysis. clustering algorithm studied, as analyzing student body mass, consisting browser, server, numerical mass testing instrument. Finally,...
ABSTRACT Background and Aim Functional gastrointestinal disorders such as chronic constipation (CC) diarrhea (CD) impose a significant burden on global healthcare resources. Food insecurity, crucial social determinant of health, remains unclearly associated with CC CD. We aim to explore the association between food insecurity CD, its impact all‐cause mortality among participants abnormal bowel health. Methods used data from National Health Nutrition Survey 2005–2010. assessed using Household...