To investigate the prevalence and epidemiological characteristics of primary palmar hyperhidrosis (PPH) among adolescents in Fuzhou City PR China.Stratified cluster sampling was carried out a cross-sectional survey by questionnaire applied 13,000 college high school students.The rate PPH 4.59% affecting both sexes equally. The peak age onset is 6-16 years, accounting for 95.6% population. Positive family history found 15.3% cases. Besides palms, axillae soles can be also affected.PPH affects...

<b><i>Background:</i></b> The management of cancer-related anorexia/cachexia syndrome (CACS) is a great challenge in clinical practice. To date, practice guidelines for the prevention and treatment CACS are lacking. authors conducted randomized study to confirm effectiveness safety utilizing megestrol acetate (MA) plus thalidomide. <b><i>Methods:</i></b> One hundred two candidates with were randomly assigned groups (trial group control group):...

Gut homeostasis is important for human health, and its disruption can lead to inflammatory bowel disease (IBD). Flos Puerariae a herb with wide variety of pharmacological activities including antioxidant, antidiabetic, antialcoholismic anti-inflammatory properties. However, the role on treating IBD remains obscure. Here, we employed Drosophila melanogaster as model organism investigate protective effect extract (FPE) against sodium dodecyl sulfate (SDS)-induced intestinal injury. Our data...

Hand grip strength (HGS) is a fast, useful, and inexpensive outcome predictor of nutritional status muscular function assessment. Numerous demographic anthropometric factors were reported to be associated with HGS, while which one or several produce greater variations in HGS has not been discussed detail. This important for answering how should normalized eliminating the influence individual differences clinical practice.To compare contribution age, sex, height, weight, forearm circumference...

Natural orifice transluminal endoscopic surgery (NOTES) has recently become a hot spot in the field of minimally invasive surgery. But, most procedures are still early stages development and limited to animal experiments. Transareolar could work as viable intermediate step before thoracic NOTES. Under intravenous anesthesia without endotracheal intubation, transareolar sympathectomy (ETS) with flexible endoscope rarely been attempted. The objective this study is evaluate feasibility safety...

Conventional endoscopic thoracic sympathectomy (ETS) is usually performed with 5-mm thoracoscope under general anesthesia endotracheal intubation. Needlescopic total intravenous without intubation has rarely been attempted. This randomized controlled trial assesses the feasibility and safety of this minimally invasive therapeutic procedure in managing primary palmar hyperhidrosis.From July 2012 to 2014, 221 patients severe hyperhidrosis underwent bilateral ETS were randomly allocated group A...

To investigate the response of tacrolimus to chronic inflammatory demyelinating polyneuropathy (CIDP) with autoantibodies against paranodal proteins, including neurofascin-155 (NF155), contactin-1 (CNTN1) and contactin-associated protein 1 (Caspr1).We retrospectively reviewed all CIDP patients who carried anti-NF155, CNTN1 Caspr1 antibodies were treated at Tongji hospital from Jan 2018 Apr 2021.There 58 only 9 had proteins (17.2%). Five received treatment an initial dose 2-3 mg once daily....

Abstract The development of physical education and health courses is not only an important element in the current stage college education, but also a crucial measure to enhance students’ fitness health. For this reason, paper based on intelligent data analysis build system research changes fitness. This first analyzes user functional requirements for analysis. clustering algorithm studied, as analyzing student body mass, consisting browser, server, numerical mass testing instrument. Finally,...

BACKGROUND: Dysfunction of the blood-spinal cord barrier (BSCB) contributes to occurrence and development neuropathic pain (NP). Previous studies revealed that activation cyclophilin A (CypA)-metalloproteinase-9 (MMP9) signaling pathway can disrupt integrity blood-brain (BBB) aggravate neuroinflammatory responses. However, roles CypA-MMP9 on BSCB in NP have not been studied. This study aimed investigate effect CypA structure function behaviors mice with NP. METHODS: We first created mouse...

The purpose of this study was to explore the change telomerase in passage from human endometrial stromal stem cells isolated endometrium. Telomerase activity cultured assessed at mRNA and protein levels using RT-PCR immunohistochemistry technique. were higher early passages, then had a gradually decreased trend immunoreactive intensity weakened positive with progressive cells. These results suggest that is contributed insenecence cell.

The mortality rate is high in patients with acute kidney injury (AKI). Hyperglycemia and hypoglycemia alone can increase the morbidity of AKI. Up to now, no relevant studies have analyzed relationship between different blood glucose levels AKI patients. Therefore, exploring baseline level 30-day provide early warning information for disease prognosis reference basis reasonable control.This retrospective cohort study was obtained from Medical Information Mart Intensive Care III (MIMIC-III)...

Objective To investigate the correlation of plasma interleukin (IL)-17 level and IL-17 receptor (IL-17R) expression in thymus patients with myasthenia gravis (MG). Methods The blood samples 63 (38 glucocorticoid treatment, 25 removal) who admitted to Henan Provincial People's Hospital between 2010 2014 were collected at three different stages: pre-treatment, 1 week post-treatment month post-treatment. The 42 healthy controls also collected. Enzyme linked immunosorbent assay was used...

目的 探讨依赖输血的再生障碍性贫血(aplastic anemia，AA)铁过载临床表现及祛铁治疗的疗效作用及安全性。 方法 回顾性分析AA患儿56例，检测长期依赖输血后铁代谢指标(血清铁、血清铁蛋白、血清转铁蛋白)状况，并观察采用铁螯合剂去铁治疗前后血象、输血频次及脏器功能的变化。 结果 依赖输血AA患儿铁代谢指标均显著升高，说明长期输血导致铁代谢紊乱，出现铁超负荷，铁过载患儿应用去铁胺治疗后，血清铁蛋白量明显减少(P<0.01)，血红蛋白量显著提高(P<0.05)，红细胞输注频率(U/30d)明显降低(P<0.01)，并且不良反应较少。 结论 AA长期输血患者应充分考虑其体内铁代谢状况，长期输血会导致输血性铁过载，而铁螯合剂去铁胺治疗输血性铁过载再生障碍性贫血有效安全，值得临床推广。

Abstract Background: The ability of the human body to balance control is influenced by cooperation muscle strength and nervous system. For steps differing heights or different cognitive tasks, there are changes in neural sensory integration that change movement strategy lower limbs. To explore rule biomechanical characteristics limbs children with thereby revealing corresponding mechanisms when descending performing thus providing much useful reference aid prevention reduction children's...

The condition of ocean underlying surface is an important factor to determine the predictability short-term climate. Different forms boundary conditions are often used in dynamic forecasting models for objects with different characteristic scales. Many institutions still using a forced general circulation model (GCM) based on given SST predict climate, but there differences degree climate prediction affected by frequencies. Considering this, this paper uses BCC National Climate Center_ Agcm3...