A5076390925- Helicobacter pylori-related gastroenterology studies
- Gut microbiota and health
- Neurological disorders and treatments
- Botulinum Toxin and Related Neurological Disorders
- Cancer-related molecular mechanisms research
- Parkinson's Disease Mechanisms and Treatments
- Vascular Malformations Diagnosis and Treatment
- Eosinophilic Esophagitis
- Intracranial Aneurysms: Treatment and Complications
- Circular RNAs in diseases
- Ocular Diseases and Behçet’s Syndrome
- Probiotics and Fermented Foods
- Inflammasome and immune disorders
- Ocular Surface and Contact Lens
- MicroRNA in disease regulation
- Insect symbiosis and bacterial influences
- Angiogenesis and VEGF in Cancer
- Acute Myeloid Leukemia Research
- Salivary Gland Disorders and Functions
- Head and Neck Cancer Studies
- Phytochemical Studies and Bioactivities
- Pharmacological Effects of Natural Compounds
- ECG Monitoring and Analysis
- Insect Utilization and Effects
- Corneal Surgery and Treatments
Yancheng First People's Hospital
2023
Affiliated Hospital of Nantong University
2023
Nantong University
2023
Nanjing Medical University
2023
Second People's Hospital of NanTong
2023
Nanjing University of Chinese Medicine
2020-2022
Qilu Hospital of Shandong University
2011-2022
Hebei Medical University
2022
Fourth Hospital of Hebei Medical University
2022
First Affiliated Hospital of Harbin Medical University
2018-2021
Retrospective consecutive case series.To review and analyze clinical presentations radiological imaging of 326 patients with spinal dural arteriovenous fistula (SDAVF) from 2 institutions.The SDAVF are nonspecific. Patients may be initially diagnosed other diseases. Magnetic resonance (MRI) can reveal cord changes associated the disorder, but neurosurgeons often overlook these changes.From 1989 to 2009, were treated at Qilu Hospital Shandong University Xuanwu Capital Medical Sciences. We...
Diabetic corneal endothelial keratopathy is an intractable ocular complication characterized by edema and decompensation, which seriously threaten vision. It has been suggested that diabetes associated with pyroptosis, a type of programmed cell death via the activation inflammation. Long noncoding RNA KCNQ1OT1 commonly various pathophysiological mechanisms diabetic complications, including cardiomyopathy retinopathy. However, whether capable regulating pyroptosis participates in pathogenesis...
Pseudomonas aeruginosa (P. aeruginosa) keratitis, a worldwide leading cause of corneal perforation and blindness, which is associated with contact lens usage. Increasing evidence has indicated that pyroptosis, novel proinflammatory programmed cell death, linked ocular diseases, little known about the role noncanonical pyroptosis in microbial keratitis. Here, we first involvement P. keratitis investigated whether wedelolactone (WDL), major active component Eclipta prostrate to target...
Although intestinal microbial dysbiosis was confirmed to be associated with many chronic diseases and health status through complicated interaction the host, effect on gastric cancer less studied. In this study, we sequenced 16S rRNA 18S genes of fecal bacteria fungi, respectively, in 134 patients 58 healthy controls matched by age gender. Propensity score matching (PSM) adopted for adjusting diet habits lifestyle, 44 (matching population) were enrolled. Serum antibody H. pylori metabolites...
Long non-coding RNA (lncRNA) H19 has been implicated in tumor angiogenesis. However, whether regulates the progression of corneal neovascularization (CNV) is unclear. The present study aimed to determine function CNV and its possible molecular mechanism. Here, we found that levels were remarkably increased vascularized corneas basic fibroblast growth factor (bFGF)-treated human umbilical vein endothelial cells (HUVECs). In vitro, up-regulation promoted proliferation, migration, tube...
Abstract Background Pathogens capable of impacting gastrointestinal tract tumor development are located in the oral cavity, but whether these bacteria able to colonize gastric mucosa cancer (GC) patients and Helicobacter pylori infection can influence this process remains be established. Methods Microbial 16S rDNA deep sequencing was conducted characterize present paired tongue coating samples 27 with superficial gastritis (SG) 11 GC patients. Results While overall composition microbiomes...
Abstract Purpose Understanding the spectrum of ocular pathogens in a given geographic region is important for devising appropriate practical treatment. Therefore, we examined pathogen and antibiotic resistance microbial keratitis northeast China. Methods In this retrospective observational study, reviewed microbiology laboratory records patients diagnosed with tertiary eye hospital Harbin, China, between 2017 2019, analysed susceptibility. Results We collected 462 specimens, which 282...
Diabetic retinopathy is the most common microvascular complication of diabetes; however, early changes in retinal microvessels are difficult to detect clinically, and a patient's vision may have begun deteriorate by time problem identified. Optical coherence tomography angiography (OCTA) an innovative tool for observing capillaries vivo. The aim this study was analyze vessel density thickness patients with diabetes.This retrospective, observational cross-sectional study. Between August 2018...
In recent years, antibiotics have frequently been detected in soil, lakes, and rivers. Antibiotic residues the environment may alter microbial structure cause bacterial resistance, but their effect on interactions among host microbiota is still poorly understood. To investigate this issue, here we used silkworm ( Bombyx mori ) fed antibiotic‐treated mulberry leaf as a model to explore effects of antibiotic exposure gut bacteria fungi. We observed that elimination fungi significantly reduced...
As a complication-prone operation, deep brain stimulation (DBS) has become the first-line surgical approach for patients with advanced Parkinson's disease (PD). This study aimed to evaluate incidence and risk factors of DBS-associated complications.We have reviewed consecutive series PD undergoing DBS procedures describe type, severity, management, outcome postoperative complications from January 2011 December 2018. Both univariate multivariate analyses were performed identify statistically...
The purpose of this study was to investigate the limbal changes in palisades Vogt (POV) patients with herpes simplex keratitis (HSK) and zoster ophthalmicus (HZO) application vivo confocal microscopy (IVCM).We enrolled 35 eyes consecutive HSK 4 HZO observational study. Thirty-five participants were also recruited from a healthy population as control group. All subjects examined by IVCM addition routine slit-lamp biomicroscopy. images corneal basal epithelial cells, nerve, corneoscleral...
Abstract Background Immune checkpoint inhibitors (ICIs) has shown remarkable benefit in the treatment of a range cancer types, although it may initiate immune related adverse events (irAEs) patients. Some studies have that there is close relationship between occurrence irAEs and prognosis. In present study, we attempted to establish whether after use anti PD-1 antibodies associated with efficacy people advanced gastric (AGC). Methods This study included patients treated anti-PD-1 for AGC at...
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective for treatment Parkinson's disease (PD). Moreover, remote programming widely used in Mainland China. This necessitates evaluating ability to achieve ideal postoperative effect. Therefore, we aimed retrospectively evaluate effects different modes on effectiveness STN-DBS 12 months postoperatively patients with PD.Clinical data were collected retrospectively, before and after surgery, 83 PD. Based voluntarily selected by...
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for advanced Parkinson's disease (PD). The G2385R variant LRRK2 a risk factor PD in Han Chinese individuals. We retrospectively compared clinical outcomes STN-DBS surgery between carriers and non-carriers. Fifty-seven patients with bilateral were enrolled, including 8 G2385R+ (G2385R+ group) 49 non-carriers (G2385R- group). Clinical data included Unified Disease Rating Scale (UPDRS) parts I to IV,...
Recent penetration depth measurement claimed the observation of unconventional superconductivity in miassite Rh$_{17}$S$_{15}$ single crystals, evidenced by linear-in-temperature at low temperatures, thereby arguing for presence lines node its superconducting gap structure. Here we measure thermal conductivity crystals down to 110 mK and up a field 8 T ($\simeq 0.4H{\rm_{c2}}$). In marked contrast measurement, observe negligible residual linear term $\kappa_0/T$ zero field, line with...
To observe the effect of adaptive replanning on adverse reactions and clinical outcome nasopharyngeal carcinoma treated by helical tomotherapy.Fifty patients TomoTherapy system were retrospectively analyzed. Among these patients, 25 received repetitive CT simulation replanning, another case-matched control without identified matching age, gender, pathological type, UICC stage, weight loss, etc. Wilcoxon test was used to evaluate acute chronic radiation within individuals. Kaplan-Meier study...
Abstract MicroRNAs (miRs) have been shown to modulate critical gene transcripts involved in tumorigenesis, but their role tumor-mediated immune suppression is largely unknown. In this study, we evaluated miRNAs that are preferentially down-regulated glioblastoma and interact with suppressive pathways as potential new therapeutics. On the basis of miRNA-gene expression libraries glioblastoma, tissue microarrays, molecular modeling, selected miR-124 lead candidate for modulating signal...
Objective To investigate the effect of innovative leads I connection right ear and left arm on ECG.Methods 116 cases with 58 men women each were equally divided into male female groups analyzed.Through collecting standard ECG arm,using statistic SPSS software,a comparative analysis was carried out between two groups.Results The both used in group,however,there no significant difference found records.Same experiment also group,and same result obtained as group.Conclusion If upper limb patient...
<title>Abstract</title> Acute myeloid leukemia is a heterogeneous disease with high morbidity and mortality under current treatment strategies. We screened the key gene thrombospondin 1 by analyzing The Cancer Genome Atlas Gene Expression Omnibus databases using bioinformatics approach further analyzed it clinical data from database. For validation, we collected bone marrow samples 20 patients acute 10 healthy controls. Quantitative polymerase chain reaction enzyme-linked immunosorbent assay...
<div>Abstract<p>Cancer is still the major cause of death across world. Regular approaches cannot effectively solve emerging problems, including drug/radiation resistance, side effects, and therapeutic ineffectiveness. Natural dietary supplements have shown effectiveness in prevention treatment cancer. Sarsaparilla (<i>Smilax Glabra</i> Rhizome) has growth-inhibitory effects on several cancer cell lines <i>in vitro</i> vivo</i>, with little toxicity...