A5100701476- Traditional Chinese Medicine Analysis
- Ginseng Biological Effects and Applications
- Autophagy in Disease and Therapy
- Traditional Chinese Medicine Studies
- Mesenchymal stem cell research
- Medicinal Plants and Neuroprotection
- Tissue Engineering and Regenerative Medicine
- Cancer-related molecular mechanisms research
- Cardiovascular Function and Risk Factors
- Chemotherapy-induced organ toxicity mitigation
- Flavonoids in Medical Research
- Natural product bioactivities and synthesis
- Plant-based Medicinal Research
- Gastric Cancer Management and Outcomes
- Erythrocyte Function and Pathophysiology
- Nephrotoxicity and Medicinal Plants
- GABA and Rice Research
- Liver physiology and pathology
- Metabolomics and Mass Spectrometry Studies
- Clusterin in disease pathology
- Cardiac electrophysiology and arrhythmias
- Spinal Cord Injury Research
- Phagocytosis and Immune Regulation
- Ginkgo biloba and Cashew Applications
- Cardiac Fibrosis and Remodeling
Suzhou University of Science and Technology
2025
China Pharmaceutical University
2018-2024
First Affiliated Hospital Zhejiang University
2024
Second Affiliated Hospital of Zhejiang University
2024
Jinzhou Medical University
2009-2022
Nanjing University of Chinese Medicine
2014-2020
Jiangsu Provincial Academy of Traditional Chinese Medicine
2013-2020
Nantong University
2020
Affiliated Hospital of Nantong University
2020
Second People’s Hospital of Huai’an
2019
Autonomous driving vehicles have strong path planning and obstacle avoidance capabilities, which provide great support to avoid traffic accidents. has become a research hotspot worldwide. Depth estimation is key technology in autonomous as it provides an important basis for accurately detecting objects avoiding collisions advance. However, the current difficulties depth include insufficient accuracy, difficulty acquiring information using monocular vision, challenge of fusing multiple...
Corydalis bungeana Turcz. (CB; family: DC.) is an anti-inflammatory medicinal herb used widely in traditional Chinese medicine (TCM) for upper respiratory tract infection, etc., but its active molecules are unknown. This study was designed to screen the components from CB based on macrophage binding combined with HPLC. Xylene-induced ear edema mouse and carrageenan-induced hind-paw rats were evaluate activity of CB. The high-performance liquid chromatography (HPLC) analysis HPLC-MS...
The migration and invasion of lung cancer cells into the extracellular matrix contributes to high mortality rates cancer. protein kinase C (PKC) downstream signaling pathways are important in cells. Calycosin (Cal), an effector chemical from Astragalus has been reported affect recurrence metastasis via regulation expression metalloproteinases (MMPs). inhibition Cal on A549 was investigated present study. Cell viability apoptosis assays were performed using MTT flow cytometric analyses. A...
Osteosarcoma (OS) is one of the most common malignant tumors in children and young adults. As chemotherapy other therapies are limited by low therapeutic efficiency, severe side effects single function, it high value to develop innovative for precise efficient treatment OS. Herein, natural photosynthetic microalgae (C. vulgaris, CV) were utilized as carriers chemotherapeutic agent doxorubicin (DOX) create a multifunctional platform (CV@DOX) photo-modulation tumor microenvironment (TME)...
Ganoderma luncidum (Leyss. ex Fr.) Karst. (GLK) has been used traditionally for the prevention and treatment of cancers or tumors a long time in Traditional Chinese Medicine. The triterpenes as main effective components GLK have found to be beneficial efficacy. purpose this study was examine anti-lung cancer activity vitro vivo explore their effects potential mechanisms. A549 cells Lewis tumor-bearing mice were evaluate inhibition on cell proliferation tumor growth. IC50 24.63 μg/mL....
Cisplatin (CDDP) is a potent antitumor compound widely used with notably side effect of nephrotoxicity inducing oxidative stress and apoptosis in kidneys. Standardized extract from the leaves Ginkgo biloba trees, labeled EGb761 (EGb), has been available on market for its beneficial effects. The purpose this study was to investigate ability EGb prevent nephrotoxic CDDP mechanisms involved. Our results showed that treatment restored levels creatinine, BUN, MDA, NO, SOD, CAT, GPx, GSSG/GSH...
Lung cancer is a common malignant tumor in clinical practice, and its morbidity mortality are the forefront of tumors. Radiotherapy, chemotherapy, surgical treatment play an important role lung cancer, however, radiotherapy has many complications even causes partial loss function, recurrence rate after resection high, toxic side effects chemotherapy drugs strong. Traditional Chinese medicine played huge prognosis improvement among them, Zengshengping (ZSP) effect preventing treating cancer....
Impaired heart function is the main reason for increased mortality of diabetes mellitus. Development drugs with cardioprotective effects against diabetic myocardiopathy would benefit patients diabetes. In this study, we tested Daming capsule (DMC), a traditional Chinese formula, on in streptozocin (STZ)-induced rats high fat-diet (HFD). DMC 100 mg/kg/d markedly decreased fasting blood glucose (FBG) and total cholesterol (TC), but did not affect triglycerides (TG) at 30 d. The rate (HR)...
Summary Acute spinal cord injury ( SCI ) leads to permanent functional deficits via mechanical and secondary mechanisms, but the therapeutic strategy for is limited. Carvedilol has been shown possess multiple biological pharmacological properties. The of present study was investigate possible protective effect carvedilol in rats. An acute rat model established neurological function tested. After (10 mg/kg, oral gavage) treatment 21 days, status osteoporosis, neuron damage, astrocyte...
In the present study, we explored whether alisol A 24-acetate (24A) and B 23-acetate (23B) induced autophagy accompanied with apoptosis nephrotoxicity via PI3K/Akt/mTOR signaling pathway in HK-2 cells. Importantly, protein expression mRNA level of Clusterin, Kim-1 TFF-3 could be significantly increased by 23B (15 μM) 24A (6 μM), which was a speculation connected HE staining rat kidneys. The results showed that both cells enhancing ratio LC3II/LC3I, Beclin-1 as well LC3 Beclin-1. Furthermore,...
Abstract The development of novel materials with effective defect‐repairing properties will help avoid subtotal gastrectomy in patients large gastric perforations. We prepared perfused decellularized matrix (PDGM) and analyzed its components, spatial structure, biomechanics, cytotoxicity, histocompatibility to validate efficacy the repair perforation. PDGM retained amounts extracellular matrix, while residual glandular cells muscle fibers were not found. structure tissue was well preserved,...
Breast cancer is characterized by a distinct metastatic pattern involving the regional lymph nodes, bone marrow, lung and liver. This study aimed to investigate effects of silencing HAS-2 gene on proliferation apoptosis human breast cells.MCF-7 cells were collected assigned into control, scrambled siRNA HAS-2- groups. After transfection, morphological changes in MCF-7 observed using phase contrast microscopy. qRT-PCR Western blot assays used detect mRNA protein expression apoptosis-related...
In order to clarify the effect of intestinal flora on absorption and metabolism paeoniflorin in vivo, by rat was studied under vitro anaerobic condition. Paeoniflorin incubated with for 48 h, UPLC used detect changes at different incubation time points following chromatographic conditions：WelchromTM C₁₈ column (4.6 mm×100 mm, 5 μm), 0.1% formic acid(A)-acetonitrile(B) as mobile phase gradient elution. The flow rate 0.4 mL•min⁻¹, temperature 30 ℃. UPLC-Q-TOF-MS positive ion mode(ESI source)...