A5086756484- Head and Neck Surgical Oncology
- Meningioma and schwannoma management
- Intracranial Aneurysms: Treatment and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Imaging and Diagnostics
- Aortic Disease and Treatment Approaches
- Cerebrospinal fluid and hydrocephalus
- Pituitary Gland Disorders and Treatments
- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Vagus Nerve Stimulation Research
- Anesthesia and Pain Management
- Cardiac and Coronary Surgery Techniques
- Cardiovascular Effects of Exercise
- COVID-19 and healthcare impacts
- Airway Management and Intubation Techniques
- Aortic aneurysm repair treatments
- Congenital Heart Disease Studies
- Cardiovascular Syncope and Autonomic Disorders
- Child Nutrition and Water Access
- Reproductive System and Pregnancy
- Child Nutrition and Feeding Issues
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Hemodynamic Monitoring and Therapy
University of Chicago
2023-2024
Vanderbilt University Medical Center
2022
University of North Carolina Hospitals
2020-2021
University of North Carolina at Chapel Hill
2012-2016
Highly prevalent conditions with multiple and complex underlying etiologies are a challenge to public health. Undernutrition, for example, affects 20% of children in the developing world. The cause consequence poor nutrition multifaceted. Undernutrition has been associated half all deaths worldwide aged <5 years; addition, its pernicious long-term effects early childhood have cognitive physical growth deficits across generations thought suppress immunity further infections reduce efficacy...
Importance The time interval between COVID-19 infection and surgery is a potentially modifiable but understudied risk factor for postoperative complications. Objective To examine the association to after diagnosis of composite major cardiovascular morbidity events within 30 days surgery. Design, Setting, Participants This single-center, retrospective cohort study was conducted among 3997 adult patients (aged ≥18 years) with previous COVID-19, as documented by positive polymerase chain...
Abstract Cuprizone intoxication is one of several animal models used to study demyelination and remyelination. Early treatment protocols exposed mice cuprizone for 6 weeks induce demyelination; however, more recent reports have varied exposure times from 4 5 weeks. The goal this was determine the minimal in C57BL/6 that would a pathology robust gliosis similar described 5‐ or 6‐week treatment. We found an abbreviated insult only 2 induced significant 3 later (5‐week time point) but somewhat...
Objective: Since the inception of endoscopic skull base surgery, it has continued to evolve through advent new technology and surgical corridors. Currently, expanded endonasal approach given us access areas previously thought not be approachable an technique. Basilar apex aneurysms are most commonly reported in posterior arterial circulation have been associated with a higher risk bleeding, mortality, morbidity than seen other locations. In addition, superior cerebellar cerebral artery less...
<b>Objective</b> To explore the use of endoscopic endonasal transclival approach (EEA) for clipping anterior inferior cerebellar artery (AICA), posterior (PICA), and vertebral (VA) aneurysms. <b>Design</b> Anatomical study. <b>Participants</b> Fifteen adult cadavers. <b>Main Outcome Measures</b> Length exposed distance from nasal ala to arteries. <b>Results</b> The length right left VA were 1.7 ± 0.6 cm 1.6 cm, respectively. was 11.1 0.9 0.8 cm. Right AICA an average 1.1 0.3 10.3 PICA a 0.5...
<b>Objective</b> To explore the feasibility of an endoscopic endonasal transclival approach to treat aneurysms arising in basilar apex, posterior cerebral arteries, and superior cerebellar arteries. <b>Study Design</b> Cadaveric anatomical study. <b>Participants</b> Fifteen cadaveric specimens. <b>Main Outcome Measures</b> Degree surgical exposure each artery attained, distance from nasal vestibule these three clipping vessels using standard vascular clip applicators. <b>Results</b> Both...
Postpneumonectomy syndrome is a rare complication in patients who have previously had pneumonectomy. Over time, the mediastinum may rotate toward vacant pleural space, which can cause extrinsic airway and esophageal compression. As such, these typically present with progressive dyspnea dysphagia. There paucity of reports anesthesiology literature regarding intraoperative anesthetic approach to such patients. We case an 18-year-old female found postpneumonectomy requiring thoracotomy...
Background: Aneurysms of the anterior communicating artery (ACoA) complex are significant clinical relevance as they most frequent all cerebral aneurysms. Within past several years, management intracranial aneurysms has shifted from clip ligation via open craniotomies to endovascular coiling, with latter increasingly being adopted preferred method treatment whenever technically feasible. This shift occurred because serious technical difficulties that surgical clipping presents. The...
Background: The endoscopic endonasal approach is a minimally invasive that provides direct access to the midline structures of skull base. This has been used for treatment different pathologies, such as skull-based tumor and pituitary resection. In recent years, this successfully utilized clipping cerebral aneurysms.