A5042688094- Lung Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Treatments and Mutations
- Corneal surgery and disorders
- Pleural and Pulmonary Diseases
- Occupational and environmental lung diseases
- Esophageal Cancer Research and Treatment
- Ocular Surface and Contact Lens
- Effects of Radiation Exposure
- Radiation Dose and Imaging
- Glaucoma and retinal disorders
- Ophthalmology and Visual Impairment Studies
- Gastric Cancer Management and Outcomes
- Medical Imaging and Pathology Studies
- Corneal Surgery and Treatments
- Head and Neck Cancer Studies
- Retinal Diseases and Treatments
- Intraocular Surgery and Lenses
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer, Hypoxia, and Metabolism
- Colorectal Cancer Treatments and Studies
- Cancer Diagnosis and Treatment
- Advanced MRI Techniques and Applications
Hebrew University of Jerusalem
2021-2025
University Medical Center
2022-2025
New York University
1950-2025
Hadassah Medical Center
1990-2024
Weill Cornell Medicine
2023
Cornell University
2023
Institute for Biomedicine
2023
New York Genome Center
2023
St Thomas' Hospital
2010-2022
King's College London
2011-2022
The effects of extra-pleural pneumonectomy (EPP) on survival and quality life in patients with malignant pleural mesothelioma have, to our knowledge, not been assessed a randomised trial. We aimed assess the clinical outcomes who were randomly assigned EPP or no context trimodal therapy Mesothelioma Radical Surgery (MARS) feasibility study.MARS was multicentre controlled trial 12 UK hospitals. Patients aged 18 years older had pathologically confirmed deemed fit enough undergo included. In...
There is evidence in some solid tumors that textural features of tumoral uptake <sup>18</sup>F-FDG PET images are associated with response to chemoradiotherapy and survival. We have investigated whether a similar relationship exists non–small cell lung cancer (NSCLC). <b>Methods:</b> Fifty-three patients (mean age, 65.8 y; 31 men, 22 women) NSCLC treated underwent pretreatment PET/CT scans. Response was assessed by CT Evaluation Criteria Solid Tumors (RECIST) at 12 wk. Overall survival (OS),...
The prevalence and degree of myopia were measured in 870 teenagers, males females. We found a statistically significant higher group 193 Orthodox Jewish male students who differed from the rest their study habits. schooling is characterized by sustained near vision frequent changes accommodation due to swaying habit during variety print size. A possible myopic effect this unique visual demand postulated.
The heart rate variability is composed of low- and high-frequency fluctuations, which are mediated by the sympathetic parasympathetic nervous systems. baseline amplitude photoplethysmographic (PPG) signal also show fluctuations in same frequencies. In current study, PPG examinations were performed on fingers normal subjects diabetic patients, three parameters derived from each pulse: pulse, its period (which equal to period). level pulse parameter was measured ratio standard deviation mean...
Purpose To determine the association between tumor heterogeneity, morphologic response, and overall survival in primary esophageal cancer treated with chemotherapy radiation therapy (CRT). Materials Methods After an institutional review board waiver was obtained, contrast material–enhanced computed tomographic (CT) studies 36 patients stage T2 or greater tumors who underwent contrast-enhanced CT before after CRT 2005 2008 were analyzed terms of whole-tumor texture, quantification entropy,...
Respiratory motion causes errors when planning and delivering radiotherapy treatment to lung cancer patients. To reduce these errors, methods of acquiring using four-dimensional computed tomography (4DCT) datasets have been developed. We developed a novel method constructing computational models from 4DCT. The attempt describe an average respiratory cycle, which reduces the effects variation between different cycles. They require substantially less memory than 4DCT dataset, are continuous in...
PurposeThe heart receives high radiation doses during therapy of advanced-stage lung cancer. We have explored associations between overall survival, cardiac doses, and electrocardiographic (ECG) changes in patients treated IDEAL-CRT, a trial isotoxically escalated concurrent chemoradiation delivering tumor 63 to 73 Gy.Methods MaterialsDosimetric survival data were analyzed for 78 patients. The whole heart, pericardium, AV node, walls left right atria (LA/RA-Wall) ventricles (LV/RV-Wall)...
To present an established practice protocol for safe and effective hospital-setting ophthalmic during the coronavirus disease 2019 (COVID-19) pandemic.
Respiratory organ motion has a significant impact on the planning and delivery of radiotherapy (RT) treatment for lung cancer. Currently widespread techniques, such as 4D-computed tomography (4DCT), cannot be used to measure variability this from one cycle next. In paper, we describe use fast magnetic resonance imaging (MRI) techniques investigate intra- inter-cycle reproducibility respiratory also estimate level errors that may introduced into by using various breath-hold strategies during...
We evaluated the long-term results of pleurectomy/decortication (P/D), hyperthermic pleural lavage with povidone-iodine, prophylactic chest wall radiotherapy (21 Gy), and systemic chemotherapy in patients malignant mesothelioma.A cohort having surgery between January 2004 December 2013 were retrospectively studied. All received postoperatively all supposed to receive chemotherapy, either preoperatively or as adjuvant therapy. Patients reviewed at 30 days, then followed up 6-monthly....
To assess the changes in computed tomography (CT) tumor heterogeneity following neoadjuvant chemotherapy esophageal cancer. Thirty-one consecutive patients who received for cancer were identified. Analysis of primary (texture) was performed on staging and post-chemotherapy CT scans. Image texture parameters (mean grey-level intensity, entropy, uniformity, kurtosis, skewness, standard deviation histogram) derived different levels image filtration (0-2.5). Proportional each parameter treatment...
Introduction Following growing evidence to support the safety, local control (LC) and potential improvement in overall survival (OS) patients with oligometastatic non-small cell lung cancer (NSCLC) that have been treated ablative therapy such as stereotactic radiotherapy (SABR) radiosurgery (SRS), we initiate SARON trial investigate impact feasibility of adding SABR/SRS radical (RRT) following standard chemotherapy on OS. Methods analysis is a large, randomised controlled, multicentre, phase...
The aim of this multi-center study was to discover and validate radiomics classifiers as image-derived biomarkers for risk stratification non-small-cell lung cancer (NSCLC). Pre-therapy PET scans from a total 358 Stage I–III NSCLC patients scheduled radiotherapy/chemo-radiotherapy acquired between October 2008 December 2013 were included in seven-institution study. A semi-automatic threshold method used segment the primary tumors. Radiomics predictive derived training set 133 using TexLAB...
Respiratory motion can vary dramatically between the planning stage and different fractions of radiotherapy treatment. Motion predictions used when constructing plan may be unsuitable for later This paper presents a methodology patient-specific respiratory models uses these to evaluate analyse inter-fraction variations in motion. The internal is determined from deformable registration Cine CT data related surrogate signal derived 3D skin surface data. Three relating have been investigated...