A5024421749- ATP Synthase and ATPases Research
- Mitochondrial Function and Pathology
- RNA modifications and cancer
- Traumatic Brain Injury and Neurovascular Disturbances
- Asthma and respiratory diseases
- IL-33, ST2, and ILC Pathways
- Neurological Disease Mechanisms and Treatments
- Metabolomics and Mass Spectrometry Studies
- Acute Ischemic Stroke Management
- Neurosurgical Procedures and Complications
- Inhalation and Respiratory Drug Delivery
- Estrogen and related hormone effects
- Spinal Fractures and Fixation Techniques
- Ferroptosis and cancer prognosis
- RNA Research and Splicing
- Innovations in Medical Education
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer, Hypoxia, and Metabolism
- Empathy and Medical Education
- Cytokine Signaling Pathways and Interactions
- interferon and immune responses
- Computational Drug Discovery Methods
- Inflammatory mediators and NSAID effects
- Radiology practices and education
Honghu Hospital of Traditional Chinese Medicine
2023-2025
Kunming Medical University
2023
Hefei Normal University
2021
University of Portsmouth
2019
Abstract Background Mitochondria are considered a primary intracellular site of reactive oxygen species (ROS) generation. Generally, cancer cells with mitochondrial genetic abnormalities (copy number change and mutations) have escalated ROS levels compared to normal cells. Since high can trigger apoptosis, treating low doses mitochondria-targeting / ROS-stimulating agents may offer cancer-specific therapy. This study aimed investigate how baseline might influence cells’ response Methods Four...
Objective: Remote site delayed extradural hematoma (RDEDH) is an uncommon but serious complication that can occur after decompressive craniectomy (DC) in patients with traumatic brain injury (TBI). This study aims to clarify the incidence, predictors, clinical and radiological characteristics, outcomes of RDEDH improve authors' understanding management this complication. Methods: identified 36 TBI who developed DC. The were analyzed retrospectively. Continuous variables compared using...
Online teaching has been confirmed as an effective method for maintaining educational quality in many courses. However, it remains unclear whether the effectiveness of face-to-face can be achieved neurosurgery clinical In this study, we aim to analyze effect online on by comparing with traditional and investigating students' willingness engage teaching, well their evaluations mode teaching. We randomly selected three classes fourth year medical students who received After completing...
Identifying the predictive factors of mortality and functional outcomes following decompressive craniectomy (DC) surgery in patients with malignant middle cerebral artery infarction (MMCAI) is essential for decision-making regarding conservative versus surgical treatment. This study aimed to assess MMCAI after DC identify associated outcomes.
Rhinovirus (RV) is the most common respiratory virus affecting humans. The majority of asthma deteriorations are triggered by RV infections. However, whether effects single‑ and double‑stranded RNA on deterioration have target genes needs to be further studied. In present study, two datasets (GSE51392 GSE30326) were used screen for differentially expressed (cDEGs). molecular function, signaling pathways, interaction networks, hub genes, key modules regulatory molecules cDEGs systematically...
Cholinesterase (ChE) is associated with the pathogenesis of chronic obstructive pulmonary disease (COPD), including airway inflammation and oxidation/antioxidant imbalance. However, relationship between serum ChE levels survival outcomes patients hospitalized acute exacerbations COPD (AECOPD) unknown. In this retrospective single-center study, we investigated ability level to predict in-hospital death in AECOPD. The clinicopathological data, as well clinical biochemical indicators were...
Abstract Background Mitochondria are considered a primary intracellular site of reactive oxygen species (ROS) generation. Generally, cancer cells with mitochondrial genetic abnormalities (copy number change and mutations) have escalated ROS levels compared to normal cells. Since high can trigger apoptosis, treating low doses mitochondria-targeting / ROS-stimulating agents may offer cancer-specific therapy. This study aimed investigate how baseline might influence cells’ response Methods Four...
Abstract Background: Solute carrier family 25 member 24 (SLC25A24) is a of the mitochondrial solute vector (MSC) protein superfamily. More and more evidence suggested that SLC members play an extremely important role in cancers. However, biological function SLC25A24 colorectal cancer has not been reported. Methods: TCGA, GEO, UALCAN, Sangebox3.0 TIDE databases were used to analyze cancer. The expression 83 pairs tissues was detected by immunohistochemistry. qRT-PCR, Western blotting...
Abstract Background Mitochondria are considered a primary intracellular site of reactive oxygen species (ROS) generation. Generally, cancer cells with mitochondrial genetic abnormalities (copy number change and mutations) have escalated ROS levels compared to normal cells. Since high can trigger apoptosis, treating low doses mitochondria-targeting / ROS-stimulating agents may offer cancer-specific therapy. This study aimed investigate how baseline might influence cells’ response Methods Four...
Abstract Background Mitochondria are considered a primary intracellular site of reactive oxygen species (ROS) generation. Generally, cancer cells with mitochondrial genetic abnormalities (copy number change and mutations) have escalated ROS levels compared to normal cells. Since high can trigger apoptosis, treating low doses mitochondria-targeting / ROS-stimulating agents may offer cancer-specific therapy. This study aimed investigate how baseline might influence cells’ response Methods Four...
Abstract Background Mitochondria are considered a primary intracellular site of reactive oxygen species (ROS) generation. Generally, cancer cells with mitochondrial genetic abnormalities (copy number change and mutations) have escalated ROS levels compared to normal cells. Since high can trigger apoptosis, treating low doses mitochondria-targeting / ROS-stimulating agents may offer cancer-specific therapy. This study aimed investigate how baseline might influence cells’ response Methods Four...
Based on network pharmacology (NP), the effects of curculigo orchioides (CO) granules alone or CO along with tamoxifen proliferation and apoptosis (P&A) human breast cancer (BC) cells were explored. A search database was constructed to obtain active components (ACs) related target genes perform disease mapping, a BC map pathway enrichment analysis (PEA). The blank control group (CG), estrogen (EG), (TG) set as controls observe tamoxifen. PEA showed that effect may be cooperation its ACs....