- Venous Thromboembolism Diagnosis and Management
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Mitochondrial Function and Pathology
- Metabolism and Genetic Disorders
- Gut microbiota and health
- Genetic Neurodegenerative Diseases
- Circular RNAs in diseases
- Fault Detection and Control Systems
- Trigeminal Neuralgia and Treatments
- Porphyrin and Phthalocyanine Chemistry
- Dysphagia Assessment and Management
- Bipolar Disorder and Treatment
- Nuclear Receptors and Signaling
- Facial Nerve Paralysis Treatment and Research
- Infectious Encephalopathies and Encephalitis
- Cerebrovascular and genetic disorders
- Neurological and metabolic disorders
- Epilepsy research and treatment
- Biomarkers in Disease Mechanisms
- Esophageal Cancer Research and Treatment
- Kruppel-like factors research
- Gene expression and cancer classification
- Dementia and Cognitive Impairment Research
- Chronic Lymphocytic Leukemia Research
Affiliated Hospital of Southwest Medical University
2018-2025
Tsinghua University
2021
China Population and Development Research Center
2021
Southwest Medical University
2015
First Affiliated Hospital of Sichuan Medical University
2015
Sichuan University
2015
Kunming University of Science and Technology
2014
<title>Abstract</title> Background Headache is one of the most common comorbidities in epilepsy, with affected patients experiencing various types headaches. This study aimed to investigate differences comorbid headache across epilepsy origins, comparing pain levels among multiple types, and exploring associations between characteristics prognosis. Methods We retrospectively analyzed consecutive adult headache, collecting comprehensive sociodemographic, epilepsy-related, headache-related...
Photoredox is a powerful synthetic tool in organic chemistry and has been widely used various fields, including nuclear medicine molecular imaging. In particular, acridinium-based organophotoredox radiolabeling significantly impacted the production discovery of positron emission tomography (PET) agents. Despite their extensive use preclinical research, no PET agents synthesized by acridinium photoredox labeling have tested humans. [18F]FDOPA clinically for tumor diagnosis evaluation...
The efficacy and safety of tirofiban in endovascular therapy for cardioembolic ischemic stroke patients remain controversial. This study aimed to evaluate the role intravenous before stroke.This post hoc analysis utilized data from RESCUE BT (Endovascular Treatment With versus Without Tirofiban Patients with Large Vessel Occlusion Stroke) trial, which was an investigator-initiated, randomized, double-blind, placebo-controlled trial. Participants were randomized receive either or a placebo...
This study aimed to investigate the cerebral blood flow (CBF) and frontal lobe cognitive function in severe internal carotid artery (ICA) stenosis patients with different types of collateral circulation.
An increasing number of studies have shown that the gut microbiome plays an important role in development coronary heart disease (CHD). However, there are no clear on relationship between and stenotic arteries. To clarify whether is associated with arteries CHD, we performed 16S rRNA gene sequencing for V3-V4 region microbiota from 9 healthy controls (C) 36 CHD patients, which including 25 patients multivessel (MV) lesion 11 single-vessel (SV) lesion. It showed abundance genus...
The transformation of vascular smooth muscle cells (VSMCs) into the proliferative migratory phenotype in plaque area contributes to stable formation and facilitates pathogenesis atherosclerosis. Stromal interaction molecule 1 (STIM1) has been identified promote proliferation VSMCs, suggesting that STIM1 may be a potent target for prevention treatment Bioinformatics analysis previously predicted as microRNA (miR)‑541‑3p. present study aimed determine effect miR‑541‑3p/STIM1 axis on...
We aimed to evaluate whether Alberta Stroke Program Early CT Score (ASPECTS) applied hyperdense lesion on noncontrast obtained immediately post-thrombectomy (post-ASPECTS) is useful for predicting poor outcome. retrospectively reviewed patients who underwent (NCCT) after mechanical thrombectomy between January 2017 and July 2020 in our comprehensive stroke center. collected baseline NCCT post-ASPECTS score. The sensitivity, specificity, positive negative predictive values of the clinical...
The free calcium oxide (f-CaO) contents directly reflects the quality of cement clinker. content can't be measured on-line at practical production and chemical analysis is complicated time consuming. A number samples has been collected from DCS control system, through data processing smart algorithms, f-CaO soft-measuring model established. Through comparative study several different kinds model, identify best soft-sensing model. calculation result shows that can effectively predict in
<title>Abstract</title> Neuronal intranuclear inclusion disease (NIID) is a rare neurodegenerative involving multiple systems and characterized by the widespread presence of eosinophilic inclusions in neurons systemic visceral cells. We report case sporadic adult-onset NIID 72-year-old female who presented with recurrent nausea vomiting as her initial symptoms. Head MRI revealed subcortical lace sign corticomedullary junction hyperintense signals middle cerebellar peduncle (MCP sign)....
Employee silence refers to the behaviour that employees are reticent when they can improve status quo of organization. We analysed 339 samples employee in information technology industry through a questionnaire survey by SPSS. Research process: 1. CFA test variables, including <tex>$\chi^{2}$</tex>, CFI, IFI and RMSEA; 2. Two-tailed was conducted for correlation variables; 3. use multiple regression model analyse causality. The research proves organizational trust mediates affects negatively...
The most malignant type of brain tumour is glioblastoma multiforme (GBM). Patients with GBM often have a poor prognosis, as result incomplete or inaccurate diagnoses. Regulatory pathways been demonstrated to serve important roles in complex human diseases. Therefore, deciphering these risk may shed light on the molecular mechanisms underlying progression. In present study, differentially expressed genes and microRNAs (miRNAs) publicly available database were identified between normal...
In this study, we develop a scale about team learning in China, combing the Chinese social culture characters such as great power distance, collectivism orientation and uncertainty avoidance. Survey data from 82 teams 14 high-technology firms are used, first to establish structural validity of by exploratory factor analysis confirmatory analysis, second test relationships between performance using regression models. Results show that there three dimensions learning, including internal...