A5100641951- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Atherosclerosis and Cardiovascular Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Neurological Disorders and Treatments
- Adipokines, Inflammation, and Metabolic Diseases
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Stroke Rehabilitation and Recovery
- Cardiovascular Disease and Adiposity
- Transcranial Magnetic Stimulation Studies
- Spatial Neglect and Hemispheric Dysfunction
- HIV, Drug Use, Sexual Risk
- Medical Research and Treatments
- Globalization, Economics, and Policies
- Cancer therapeutics and mechanisms
- Dementia and Cognitive Impairment Research
- Explainable Artificial Intelligence (XAI)
- Traditional Chinese Medicine Analysis
- Environmental Conservation and Management
- Coastal wetland ecosystem dynamics
- Moyamoya disease diagnosis and treatment
- Parkinson's Disease Mechanisms and Treatments
Shandong Xiehe University
2025
University of Electronic Science and Technology of China
2024
Affiliated Hospital of Southwest Medical University
2017-2024
Deyang Stomatological Hospital
2024
Fuyang City People's Hospital
2019-2024
Mianyang Central Hospital
2024
Southwest Medical University
2014-2024
The First People's Hospital of Wenling
2024
Yang Hospital
2024
Xian Yang Central Hospital
2024
Stroke and its risk factors epidemiological survey can help identify individuals at higher therefore promote stroke prevention strategies. The aim of this study was to estimate the current prevalence high population, evaluate associated in southwestern China.This a multi-center, cross sectional China from May 2015 September 2015. eight communities were selected random, 17,413 residents aged ≥40 years volunteered participate survey. Data collected through face-to-face using structured...
Background and Purpose—Early presentation is critical for receiving effective reperfusion therapy acute ischemic stroke, therefore, we undertook a national survey of awareness responses to stroke symptoms in China. Methods—We cross-sectional community-based study 187 723 adults (age ≥40 years) presenting 69 administrative areas across China between January 2017 May determine the recognition rate correct action rate. Multivariable logistic regression models were used identify factors...
This study investigated the link between triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio and nonalcoholic fatty liver disease (NAFLD) fibrosis in American adults.
Eicosanoids may play a role in ischemic stroke. However, the associations of variants cyclooxygenase (COX) pathway genes and interaction among these with carotid plaque vulnerability are not fully understood. In present study, twelve COX were examined using matrix-assisted laser desorption ionization time-of-flight mass spectrometry method 396 patients stroke 291 controls. Platelet aggregation, platelet-leukocyte aggregates, urine 11-dehydrothromboxane B2 (11-dTxB2) also measured. According...
With the aging of population and change lifestyle in China, prevalence risk factors high-risk for stroke may change. However, few studies performed community-based surveys China. Hence, we this multicenter, cross-sectional, survey Sichuan southwestern according to China National Stroke Screening Survey (CNSSS) program 2015. The residents aged ≥ 40 years volunteered participate face-to-face 8 communities Sichuan. were selected using cluster randomization method. Subjects with at least three...
Abstract Objectives To investigate the relationships between 18 single nucleotide polymorphisms with carotid atherosclerosis and whether interactions among these genes were associated an increased risk of atherosclerosis. Methods Face‐to‐face surveys conducted individuals aged 40 or older in eight communities. A total 2377 included study. Ultrasound was used to detect population. loci 10 inflammation endothelial function detected. Gene‐gene analyzed using generalized multifactor...
To evaluate the relationship between carotid stenosis with variants in genes referred to inflammation and endothelial function.There was a multi-center, cross sectional survey southwestern China. The eight communities were selected at random residents aged ≥40 years volunteered participate face-to-face survey. Subjects least three of aforementioned stroke related risk factors or history classified as high-risk population for stroke. A total 2,377 subjects communities, degree assessed by...
Abstract. To explore the interactions between chole‐cystokinin (CCK) and cholinergic system, we compared effect of or peptidergic CCK blockade on gallbladder contraction pancreatic enzyme secretion using atropine loxiglumide (a specific antagonist) as pharmacological tools. Gallbladder was measured by sonography a marker perfusion aspiration technique. Graded doses exogenous CCK8 induced dose‐dependent contractions increasing outputs. Loxiglumide (10 mg kg ‐1 h ) abolished response prevented...
Aim: To examine the association between carotid plaque and variants in genes involved inflammation endothelial function.
This study aimed to investigate the cerebral blood flow (CBF) and frontal lobe cognitive function in severe internal carotid artery (ICA) stenosis patients with different types of collateral circulation.
To investigate the potential association between polymorphisms in genes involved endothelial function, inflammation and carotid atherosclerosis.This was a three-center, population-based sectional survey conducted Sichuan province of southwestern China. We randomly selected 8 different communities Sichuan, residents each community volunteered to participate by face-to-face questionnaire. A total 2,377 with high stroke risk population were included. Carotid atherosclerosis evaluated...
Neuropsychiatric symptoms (NPS) have been shown to affect the progression and development of Alzheimer's disease (AD) in elderly. However, published data are still controversial limited large cohort-based NPS study.
Cholangiocarcinoma is an aggressive and heterogeneous malignancy originating from the bile duct epithelium. It associated with poor prognosis high mortality. The global incidence of cholangiocarcinoma rising, there urgent need for effective early diagnosis treatment strategies to reduce burden this devastating tumor. Small extracellular vesicles, including exosomes microparticles, are nanoscale vesicles formed by membranes that released both normally pathologically cells, mediating...
Aim To identify the associations of 19 single nucleotide polymorphisms (SNPs) in genes involved inflammation and endothelial function carotid atherosclerosis with subsequent ischemic stroke other vascular events high-risk population. Methods This was a multicenter community-based sectional survey prospective cohort study Sichuan, southwestern China. Eight communities were randomly selected, residents each community surveyed using structured face-to-face questionnaire. Carotid ultrasonography...
Aim: To evaluate the effect of prestroke aspirin (PA) use on initial stroke severity, early neurologic deterioration (END), recurrence, hemorrhagic transformation (HT), and functional outcome in patients with ischemic (IS).
: Few studies have examined the effect of rTMS on impaired emotional processing in apathetic Parkinson's disease (PD) patients, which impelled us to use a combination repetitive transcranial magnetic stimulation (rTMS) with event-related potentials (ERPs) gain insight into underlying mechanisms. Apathetic and non-apathetic patients diagnosed PD performed facial emotion categorization task, ERP data were collected before after HF-rTMS or sham over right dorsolateral prefrontal cortex (DLPFC)....
The mechanisms of ischemic stroke severity and early neurologic deterioration (END) are not fully understood. aim the present study was to investigate association six variants in MMP-9 gene with risk for END (IS) patients atrial fibrillation (AF).This a multi-center, prospective, observational 615 acute IS AF admitted participating hospitals between June 2016 October 2017. Ischemic assessed using National Institutes Health Stroke Scale (NIHSS) score on admission. defined as an increase four...
We aimed to evaluate whether Alberta Stroke Program Early CT Score (ASPECTS) applied hyperdense lesion on noncontrast obtained immediately post-thrombectomy (post-ASPECTS) is useful for predicting poor outcome. retrospectively reviewed patients who underwent (NCCT) after mechanical thrombectomy between January 2017 and July 2020 in our comprehensive stroke center. collected baseline NCCT post-ASPECTS score. The sensitivity, specificity, positive negative predictive values of the clinical...
Abstract The objective of this study was to compare clinical outcomes in patients who with unfavorable vascular anatomy underwent mechanical thrombectomy (MT) by common carotid artery access versus transfemoral approach. A retrospective review performed our hospital database identify challenging MT for anterior circulation large vessel occlusion (LVO) between August 2015 and November 2018. Transcarotid cohorts were compared. Patient characteristics, procedural techniques, recorded. total 52...
Purpose To investigate the effect of two weeks repetitive transcranial magnetic stimulation (rTMS) on attention network in Parkinson’s disease (PD) patients.Materials and methods Sixty PD patients were randomly divided into equal-sized active- sham-rTMS groups. Executive function was assessed by neuropsychological tests including Trail-Making Test (TMT), word fluency test, digit span, Wisconsin Card Sorting (WCST) Stroop test. The evaluated test (ANT). rTMS (5 Hz) applied over left...
<title>Abstract</title> Background: Stroke and its risk factors epidemiological survey can help identify individuals at higher therefore promote stroke prevention strategies. The aim of this study was to estimate the current prevalence high population, evaluate associated in southwestern China. Methods: This a multi-center, cross sectional China from May 2015 September 2015. 8 communities were selected random, 17413 residents aged ≥ 40 years volunteered participate survey. Data collected...
The high-risk stroke populations are significantly associated with an increased risk of or other vascular events. Although proven primary and secondary prevention medications available, persistent use is required to be effective. However, the persistence drug therapy its association outcomes in population have received limited study China. Hence, according China National Stroke Screening Survey (CNSSS) program 2015, we performed this multicenter population-based cross-sectional survey...