A5100783688- Breast Cancer Treatment Studies
- Gastric Cancer Management and Outcomes
- Advanced Breast Cancer Therapies
- Colorectal Cancer Screening and Detection
- Estrogen and related hormone effects
- Cholangiocarcinoma and Gallbladder Cancer Studies
- BRCA gene mutations in cancer
- Berberine and alkaloids research
- Cardiac Fibrosis and Remodeling
- Lung Cancer Diagnosis and Treatment
- HER2/EGFR in Cancer Research
- PI3K/AKT/mTOR signaling in cancer
- Food Security and Health in Diverse Populations
- Breast Implant and Reconstruction
- Plant chemical constituents analysis
- Autophagy in Disease and Therapy
- Caveolin-1 and cellular processes
- Health disparities and outcomes
- Pancreatic and Hepatic Oncology Research
- RNA Interference and Gene Delivery
- Botanical Research and Chemistry
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Genetic factors in colorectal cancer
- Pediatric Hepatobiliary Diseases and Treatments
- Cancer-related molecular mechanisms research
The Affiliated Yongchuan Hospital of Chongqing Medical University
2017-2024
Chongqing Medical University
2017-2024
Army Medical University
2023
Naval Medical Research Command
2021
Northwest University
2020
Chongqing Cancer Hospital
2018
Chinese PLA General Hospital
2014
National Institute for Radiological Protection
2014
Chinese Center For Disease Control and Prevention
2014
and Importance: Growing gastrointestinal cancers in the U.S. necessitate further research due to substantial healthcare economic impacts. This study aims analyze trends future projections for five major (colorectal, pancreatic, liver, stomach, esophageal).
During the past decade, concept of complete mesocolic excision (CME) has been developed in an attempt to minimize recurrence for right-sided colon cancer. This study aims compare outcomes robotic versus laparoscopic right hemicolectomy with CME cancer.We performed a retrospective multicenter propensity score matching study. From July 2016 2021, 382 consecutive patients from different Chinese surgical departments were available inclusion out initial cohort 412, who underwent or CME. Data all...
Sphingosine kinase 1 (SPHK1) is a bioactive lipid mediator that has been identified as biomarker in various cancers and considered to play an important role tumor progression. In the present study, expression level of SPHK1 was examined breast cancer clinical specimens, its association with patient survival investigated clarify significance cancer. mRNA increased tissues compared matched adjacent 19 32 paired tissue specimens (59.4%). Immunohistochemical analysis 122 cases revealed levels...
Schinifoline (SF), a 4-quinolinone derivative, was found in Zanthoxylum schinifolium for the first time. 4-Quinolinone moieties are thought to have cytotoxic activity and often used as tubulin polymerization inhibitors, heterogeneous enzyme inhibitors antiplatelet agents. However, very little information respect radiosensitization has focused on SF. This work aimed investigate radiosensitizing effect of SF A549 cells. The cell viability results indicated cytotoxicity cells, with IC50 values...
Trastuzumab resistance has emerged as a major issue in anti-human epidermal growth factor receptor-2 (HER2) therapy for breast cancers. The cell lines maintain overexpression of HER2. Upon treatment with trastuzumab, R-SKBR3 and R-BT474 displayed an increased rate invasiveness, accompanied by activation the ERK1/2 AKT signaling pathways, also parental EMT-like transition (epithelial-mesenchymal transition) was promoted, increases N-cadherin, vimentin, fibronectin decrease E-cadherin. A...
One new alkaloid, together with 10 known compounds were isolated from the aerial parts of Chelidonium majus L. by repeated silica gel column chromatography. Their chemical structures elucidated on basis physicochemical and spectroscopic data. Among them, 6-acetonyldihydrochelerythrine (4), 6-acetonyldihydrosanguinarine (5), 6-ketenesanguinarine (6), demethylchelerythrine (7) demethylsanguinarine (11) for first time this plant. Compound 6 was identified as a compound. These screened...
Background: Racial and ethnic disparities in mortality continue to persist US cancer survivors. Social determinants of health (SDoH) may have important direct or indirect influence on patient survivals.Methods: A population-based cohort study a nationally representative sample adult survivors (n = 5163; weighted population, 32 623 176), who participated the National Health Nutrition Examination Survey from 1999–2018 were included. Individuals’ death data linked Death Index their interview...
Hormone receptor-positive breast cancer (BC) is the most prevalent subtype of BC and generally correlated with a favorable prognosis. This study aimed to determine incidence survival trends among women diagnosed hormone between 1990 2019. Female patients for calendar years 1990-2019 were obtained from Surveillance, Epidemiology, End Results (SEER) database categorized into six diagnostic groups according year diagnosis. Age-adjusted rates (IRs) calculated using joinpoint regression. We used...
<title>Abstract</title> Hormone receptor-positive breast cancer (BC) is the most prevalent subtype of BC and generally correlated with a favorable prognosis. This study aimed to determine incidence survival trends among women diagnosed hormone between 1990 2019.<bold> </bold>Female patients for calendar years 1990–2019 were obtained from Surveillance, Epidemiology, End Results (SEER) database categorized into six diagnostic groups according year diagnosis. Age-adjusted rates (IRs) calculated...
Introduction This investigation determined the cardioprotective activity of mRNA-103 inhibitor against myocardial infarction (MI) and also evaluated its molecular mechanism. Material methods MI was induced in rats by inducing ischaemia/reperfusion (I/R), left ventricular (LV) (1 × 10<sup>7</sup> TU) injected into myocardium around infarcted area. The effect assessed determining levels enzymes cytokines serum, myeloperoxidase (MPO) activity, Toll-like receptor 4 (TLR4), nuclear...
Background: To evaluate the performance of a machine learning approach to predict pulmonary function test (PFT) result from parameter response mapping (PRM), which enhances value one-stop CT scanning.Methods: 615 subjects with PFT and paired inspiratory expiratory chest scanning were enrolled retrospectively, classified into normal group, high risk group COPD based on PFT. 72 PRM-derived quantitative parameters including volume (cc) percentage (%) emphysema, functional-small airways disease...