A5083670989- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- RNA modifications and cancer
- Cancer Genomics and Diagnostics
- Immune cells in cancer
- Gastrointestinal disorders and treatments
- Inflammatory Myopathies and Dermatomyositis
- Influenza Virus Research Studies
- Single-cell and spatial transcriptomics
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Surgical Treatments
- Cardiomyopathy and Myosin Studies
- Respiratory viral infections research
- Cancer-related molecular mechanisms research
- Anorectal Disease Treatments and Outcomes
- Muscle Physiology and Disorders
- Mitochondrial Function and Pathology
- IgG4-Related and Inflammatory Diseases
- RNA Research and Splicing
- COVID-19 and healthcare impacts
Shangluo University
2024
Zhongshan Hospital
2013-2023
Fudan University
2013-2023
Peking University
2019-2023
Chinese PLA General Hospital
2017-2023
Shaanxi Normal University
2020-2023
Shenzhen Polytechnic
2009-2023
Jiangsu Hengrui Medicine (China)
2023
First Hospital of Shanxi Medical University
2020-2022
Shanxi Medical University
2020-2022
Successful closure of wall defects is the key procedure following endoscopic full-thickness resection (EFTR). In this report we describe a new method similar to interrupted suture repair gastric by means endoloops and metallic clips.We retrospectively analyzed 20 patients who presented at our institute between March 2011 February 2012 with submucosal tumors consequently underwent EFTR, resulting large being closed using clips. Tumor characteristics, en bloc rates, postoperative complications...
<b>Background and study aims:</b> Endoscopic submucosal dissection (ESD) is accepted as an established treatment modality for superficial esophageal carcinoma (SEC). The aim of this was to identify risk factors postoperative stricture after ESD SEC. <b>Patients methods:</b> This a retrospective at single institution. A total 362 patients with SEC treated by Zhongshan Hospital, Shanghai, were enrolled between January 2007 February 2012. Demographic clinical parameters, including patient-,...
Abstract Background NOD-like receptors affect multiple stages of cancer progression in many malignancies. NACHT, LRR, and PYD domain-containing protein 7 (NLRP7) is a member the receptor family, although its role tumorigenesis remains unclear. By analyzing clinical samples, we found that NLRP7 levels were upregulated colorectal (CRC). We proposed hypothesis high level CRC may promote tumor progression. Here, further investigated underlying mechanism. Methods expression human adjacent...
The molecular mechanisms underlying colorectal cancer (CRC) tumorigenesis remain incompletely understood, partially contributing to the mortality of CRC. Advances in identification novel are therefore an urgent need fill gap our knowledge CRC development. Here, we performed both vitro and vivo experiments along with silico analysis identify a new regulatory circuit that stimulated tumorigenesis. In this report, we, for first time, analyzed correlation FIH-1 level clinicopathological features...
Abstract Background According to the Japanese Esophageal Society (JES) guidelines, early esophageal squamous cell carcinoma (SCC) involving muscularis mucosae (M3) or upper submucosal (SM1) layers are relative indications for endoscopic dissection (ESD). Additional esophagectomy chemoradiotherapy is recommended patients with after evaluation. However, elderly (≥ 60 years) in China often refuse additional treatment because of debilitating side effects. The aim this study was evaluate...
Objective To investigate the characteristics of cardiac involvement due to Immune-mediated Necrotizing Myopathy (IMNM). Methods Patients diagnosed with (IMNM) who attended Department Neurology and Rheumatology Immunology at First Medical Center PLA General Hospital between February 2011 June 2022 were collected. Clinicopathological diagnosis IMNM was performed according criteria established by European Neuromuscular (ENMC). All patients underwent muscle biopsy Myositis-specific antibodies...
Colorectal cancer (CRC) is one of the most common cancers worldwide. The molecular mechanisms underlying CRC development involve a multistep process with accumulation both genetic and epigenetic changes. To deeply understand tumorigenesis progression, advances in identification novel key factors are therefore an urgent need. Here, we examined correlation factor inhibiting HIF-1α (FIH-1) expression clinicopathological features CRC. finding that FIH-1 was not only significantly decreased tumor...
The Environmental Cooperation System (ECS) is a new exploration of the government’s spatial environmental policy to meet requirements green and sustainable development, so it very important scientifically evaluate its innovation effect. Based on China’s A-share listed companies from 2006 2021, perspective corporate ESG performance, we apply multi-dimensional fixed-effects difference-in-differences (DID) model, empirically test impact, mechanism, heterogeneity Shenzhen-Dongguan-Huizhou...
There are many reports on the endoscopic management of ingested foreign bodies in upper gastrointestinal tract, however, little is known about a specific subset esophageal – impacted (IEFBs), especially perforating (PEFBs). The aim this retrospective study 78 cases was to report experience and outcome IEFBs Chinese patients. From January 2006 July 2011, total 750 patients with suspected were admitted endoscopy center. Among these patients, that met defined criteria retrospectively enrolled...
Both tumor and adjacent normal tissues are valuable in cancer research. Transcriptional response profiles represent the changes of gene expression levels between paired tissues. In this study, we performed a pan-cancer analysis based on transcriptional from 633 samples across 13 types. We obtained two interesting results. Using consensus clustering method, characterized ten clusters with distinct patterns enriched pathways. Notably, head neck squamous cell carcinoma was divided subtypes,...
In recent years, systemic chemotherapy and molecular targeted therapy have become standard first-line treatments for locally advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC). The objective of this survey was to investigate anticancer treatment patterns gene aberration test status patients with NSCLC in China. Patients included study had unresectable Stage IIIB/IV were admitted during August 2015 March 2016 into one 12 tertiary hospitals throughout China treatment....
Dermatomyositis (DM) and polymyositis (PM) are common inflammatory myopathies whose immunopathogenic mechanisms remain poorly understood. The NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome is a type of cytoplasmic multiprotein responsible for the activation reactivations. Responding to wide range exogenous endogenous microbial or sterile stimuli, NLRP3 inflammasomes can cleave pro-caspase-1 into active caspase-1, which processes pro-inflammatory cytokines...
Abstract Breast cancer is a disease with high heterogeneity. Many issues on tumorigenesis and progression are still elusive. It critical to identify genes that play important roles in the of tumors, especially for tumors poor prognosis such as basal-like breast very young women. To facilitate identification potential regulatory or driver genes, we present Cancer Integrative Platform (BCIP, http://www.omicsnet.org/bcancer/ ). BCIP maintains multi-omics data selected strict quality control...
Endoscopic full-thickness resection (EFTR) derived from endoscopic submucosal dissection has gradually been accepted and even promoted for the treatment of tumors (SMTs) originating muscularis propria (MP) layer. However, there are some difficulties when EFTR is used to treat MP lesions in gastric fundus. This study intends explore whether can be made simpler, safer, more effective with traction assistance dental floss.The clinical data patients (trial group) layer fundus undergoing floss at...