A5036061828- Plant Pathogenic Bacteria Studies
- Plant-Microbe Interactions and Immunity
- Legume Nitrogen Fixing Symbiosis
- Genomics and Phylogenetic Studies
- Infections and bacterial resistance
- Plant Pathogens and Fungal Diseases
- Nematode management and characterization studies
- Bacterial biofilms and quorum sensing
- Antibiotic Resistance in Bacteria
- Vibrio bacteria research studies
- Plant Disease Resistance and Genetics
- Wheat and Barley Genetics and Pathology
- Cystic Fibrosis Research Advances
- Banana Cultivation and Research
- Insect symbiosis and bacterial influences
- Protist diversity and phylogeny
- Mycobacterium research and diagnosis
- Microbial Community Ecology and Physiology
- Bacteriophages and microbial interactions
- RNA Interference and Gene Delivery
- Phytoplasmas and Hemiptera pathogens
- Agricultural Science and Fertilization
- Entomopathogenic Microorganisms in Pest Control
- Agricultural Practices and Plant Genetics
- Agriculture, Plant Science, Crop Management
Institute of Microbial Technology
2012-2023
Oxford Nanopore Technologies (United Kingdom)
2023
University of Liverpool
2018-2021
Council of Scientific and Industrial Research
2012-2016
Princeton University
1996
Surveillance of the extracellular environment by immune receptors is central importance to eukaryotic survival. The rice receptor kinase XA21, which confers robust resistance most strains Gram-negative bacterium Xanthomonas oryzae pv. (Xoo), representative a large class cell surface in plants and animals. We report identification previously undescribed Xoo protein, called RaxX, required for activation XA21-mediated immunity. that lack or carry mutations single RaxX tyrosine residue (Y41),...
A promising class of compounds for DNA transfection have been designed by conjugating various polyamines to bile-acid-based amphiphiles. Formulations containing these were tested their ability facilitate the uptake a beta-galactosidase reporter plasmid into COS-7 cells. Dioleoyl phosphatidyl ethanolamine (DOPE) formulations some several times better than Lipofectin at promoting uptake. The most active contained hydrophilic bile acid components. activity is clearly not related affinity DNA:...
DATA REPORT article Front. Microbiol., 11 January 2016Sec. Plant Pathogen Interactions Volume 6 - 2015 | https://doi.org/10.3389/fmicb.2015.01551
ABSTRACT Citrus canker, caused by Xanthomonas citri pv. citri, is a serious disease of citrus plants worldwide. Earlier phylogenetic studies using housekeeping genes revealed that X. related to many other pathovars, which can be collectively referred as pathovars (XCPs). From the present study, we report genome sequences 18 XCPs and compared them with four available in public domain. In tree based on phylogenomic marker genes, all form monophyletic cluster, suggesting their origin from...
Abstract Xanthomonas oryzae pv. ( Xoo ) is a serious pathogen of rice causing bacterial leaf blight disease. Resistant varieties and breeding programs are being hampered by the emergence highly virulent strains. Herein we report population based whole genome sequencing analysis 100 strains from India. Phylogenomic revealed clustering India along with other Asian strains, distinct African US Xo The Indian consists major clonal lineage four minor but diverse lineages. Interestingly, variant...
DATA REPORT article Front. Microbiol., 10 March 2016Sec. Evolutionary and Genomic Microbiology Volume 7 - 2016 | https://doi.org/10.3389/fmicb.2016.00309
ABSTRACT Xanthomonas axonopodis pv. citri (Xac) is the causal agent of citrus bacterial canker (CBC) and a serious problem worldwide. Like CBC, several important diseases in other fruits, such as mango, pomegranate, grape, are also caused by pathovars that display remarkable specificity toward their hosts. While mango were documented more than 100 years ago, pomegranate grape have been known only since 1950s 1970s, respectively. Interestingly, all these noted first India. Our genome-based...
Stenotrophomonas maltophilia has evolved as one of the leading multidrug-resistant pathogens responsible for a variety nosocomial infections especially in highly debilitated patients. As information on genomic and intraspecies diversity this clinically important pathogen is limited, we sequenced whole genome 27 clinical isolates from hospitalized Phylogenomic analysis along with genomes type strains suggested that are distributed over complex (Smc) within genus . Further genome-based...
Bacterial endosymbiosis has been instrumental in eukaryotic evolution, and includes both mutualistic, dependent parasitic associations. Here we characterize an intracellular bacterium inhabiting the flagellated protist Bodo saltans (Kinetoplastida). We present a complete bacterial genome comprising 1.39 Mb circular chromosome with 40.6% GC content. Fluorescent situ hybridisation confirms that endosymbiont is located adjacent to nuclear membrane, detailed model of its niche generated using...
We report the 5.18-Mb genome sequence of Brevibacillus laterosporus strain GI-9, isolated from a subsurface soil sample during screen for novel strains producing antimicrobial compounds. The draft this will aid in biotechnological exploitation and comparative genomics strains.
We report the 4.94-Mb genome sequence of Xanthomonas axonopodis pv. punicae strain LMG 859, causal agent bacterial leaf blight disease in pomegranate. The draft will aid comparative genomics, epidemiological studies, and quarantine this devastating phytopathogen.
The rice bacterial blight pathogen Xanthomonas oryzae pv. ( Xoo ) injects transcription activator-like effectors (TALEs) that bind and activate host “susceptibility” S genes important for disease. Clade III SWEET are major blight. resistance xa5 , which reduces TALE activity generally, xa13 a SWEET11 allele not recognized by the cognate TALE, have been effectively deployed. However, strains defeat both individually were recently reported in India Thailand. To gain insight into mechanism(s),...
ABSTRACT We report the 1.8-Mb genome sequence of Pediococcus pentosaceus strain IE-3, isolated from a dairy effluent sample. The whole-genome this will aid in comparative genomics strains diverse ecological origins and their biotechnological applications.
The rice bacterial blight pathogen Xanthomonas oryzae pv. (Xoo) constrains production in major growing countries of Asia. Xoo injects transcription activator-like effectors (TALEs) that bind to and activate host "susceptibility" (S) genes are important for disease. resistance gene xa5, which reduces TALE activity generally, has been widely deployed. However, strains defeating xa5 have reported India recently also Thailand. We completely sequenced compared the genomes one such strain from...
Abstract Burkholderia cepacia complex (Bcc) is a group of bacteria causing opportunistic infections in immunocompromised and cystic fibrosis (CF) patients. Herein, we report multilocus sequence typing analysis the 57 clinical isolates Bcc collected over period seven years (2005–2012) from several hospitals across India. A total 21 types (ST) including two STs patient’s twelve novel were identified population reflecting extent genetic diversity. Multilocus revealed lineages population, major...
ABSTRACT We report the 5.1-Mb genome sequence of Xanthomonas citri pv. mangiferaeindicae strain LMG 941, causal agent bacterial black spot in mango. Apart from evolutionary studies, draft will be a valuable resource for epidemiological studies and quarantine this phytopathogen.
Burkholderia cenocepacia is a clinically dominant form among the other virulent species of cepacia complex (Bcc). In present study, we sequenced and analyzed genomes seven nosocomial Bcc isolates, five which were isolated from bloodstream infections two isolates recovered hospital setting during surveillance. Genome-based identification using type strain explicitly identified as B. cenocepacia. Moreover, single nucleotide polymorphism analysis revealed that six clonal phylogenetically...
Abstract Xanthomonas oryzae is a devastating pathogen of rice worldwide, however, X. sontii and maliensis are its non-pathogenic counterparts from the same host. So far, these isolates were overlooked due to their less economic importance lack genomic information. We have carried out detailed ecological evolutionary study focusing on diverse lifestyles strains. Phylogenomic analysis revealed two major lineages corresponding (ML-I) (ML-II) species. Interestingly, one strains belonging...
Abstract Three yellow pigmented, Gram negative, aerobic, rod shaped, motile bacterial strains designated as PPL1, PPL2 and PPL3 were isolated from healthy basmati rice seeds. Phenotypic, biochemical 16S rRNA gene sequence analysis assigned these to the genus Xanthomonas . The was having 99.59% similarity with X. sacchari CFBP4641 T However, whole genome based phylogenomic revealed that formed a distinct monophyletic clade their closest neighbour. Taxonogenomic studies on average nucleotide...
Acinetobacter baumannii resistance to carbapenems is of global concern. Here, we report the 3.9 Mb draft genome a cerebrospinal fluid isolate A. strain 10441_14 which carbapenem resistant and belongs ST451. This will further help in understanding drug mechanism, epidemiology, pathology this bacterium.
Stenotrophomonas maltophilia is a typical example of an environmental originated opportunistic human pathogen, which can thrive at different habitats including the body and cause wide range infections. It must cope with heat stress during transition from environment to as physiological temperature (37 °C) higher than niches (22–30 °C). Interestingly, S. rhizophila phylogenetic neighbour within genus unable grow 37 °C. Thus, it crucial understand how adapted temperature, could suggest its...
We report here the 4.1-Mb draft genome sequence of Acinetobacter baumannii strain 5021_13, a cerebrospinal fluid isolate from northern India. This information will help studies toward understanding epidemiology and pathogenicity this important nosocomial pathogen.