A5100624041- Biological and pharmacological studies of plants
- Traditional Chinese Medicine Analysis
- Metabolomics and Mass Spectrometry Studies
- Ginkgo biloba and Cashew Applications
- Flavonoids in Medical Research
- Food Quality and Safety Studies
- Bioactive natural compounds
- Ginseng Biological Effects and Applications
- Phytoestrogen effects and research
- Tea Polyphenols and Effects
- Alzheimer's disease research and treatments
- Biochemical effects in animals
- Medicinal Plants and Bioactive Compounds
- Saffron Plant Research Studies
- Full-Duplex Wireless Communications
- Morinda citrifolia extract uses
- Analytical chemistry methods development
- Reproductive biology and impacts on aquatic species
- Polysaccharides Composition and Applications
- Cancer, Lipids, and Metabolism
- Heat shock proteins research
- Glycosylation and Glycoproteins Research
- Polyomavirus and related diseases
- Medicinal Plants and Neuroprotection
- Genetics, Aging, and Longevity in Model Organisms
Shandong University of Traditional Chinese Medicine
2018-2025
Hanshan Normal University
2024
Nanjing University
2002-2023
Nanjing General Hospital of Nanjing Military Command
2013-2023
Nanjing Medical University
2011-2023
Hunan Normal University
2021
Hunan Provincial People's Hospital
2021
Shandong Academy of Sciences
2018-2019
Qilu University of Technology
2018-2019
Chinese Academy of Medical Sciences & Peking Union Medical College
2014-2019
In this paper, highly selective core–shell molecularly imprinted polymers (MIPs) of tadalafil on the surface magnetic nanoparticles (MNPs) were prepared. Three widely used functional monomers 2-(trifluoromethyl) acrylic acid (TFMAA), (AA), and methacrylic (MAA) compared theoretically as candidates for MIP preparation. MIP-coated (MIP-coated MNPs) showed large adsorption capacity, high recognition ability, fast binding kinetics tadalafil. Furthermore, because good properties, MNPs can achieve...
Abstract Non‐small‐cell lung cancer (NSCLC), in which the NF‐κB pathway is constitutively activated, one of most common malignancies. Herein, we identify an E3 ubiquitin ligase, tripartite motif‐containing 37 (TRIM37), participating K63 polyubiquitination TRAF2, a significant step activation signaling. Both mRNA and protein expression levels TRIM37 were much higher NSCLC cell lines tissues than normal bronchial epithelial cells matched adjacent non‐tumor tissues. correlated closely with...
To explore the transformation mechanisms of free gastrodin and combined before after steaming Gastrodia elata (G. elata), a fresh G. sample was processed by traditional method prescribed Chinese Pharmacopoeia (2015 version), HPLC-ESI-TOF/MS used to identify chemical composition in steamed elata. Finally, 25 components were identified based on characteristic fragments compounds changes compared relative content. Hydrolysis experiments enzymatic hydrolysis 10 monomer simulating process carried...
When brain injury happens, endogenous neural stem cells (NSCs) located in the adult subventricular zone (SVZ) and subgranular (SGZ) are attacked by ischemia/reperfusion to undergo cellular apoptosis death before being induced migrate lesion point differentiate into mature for damaged cell replacement. Although promoting antiapoptosis NSC survival critical neuroregeneration, mechanism has yet been elucidated clearly. Here this study, we established an vitro oxygen‐glucose deprivation...
Abstract Different aromatic components do indeed give different tea flavors. There is still little research on whether there a certain regularity in the combination and content of aroma types Phoenix Dancong (PDC) tea. This potential may be key factor unraveling relationship between reproduction evolution PDC Here, 5 kinds these 4 (Zhuye, Tuofu, Jianghuaxiang, Juduo, Yashixiang) were used as materials this study, headspace solid-phase microextraction combined with gas chromatography–mass...
Four new gastrodin derivatives containing a trans-cinnamoyl unit (1–4) and nine known compounds (5–13) were isolated from the rhizomes of Gastrodia elata Blume. All these evaluated for their neuroprotective effects against 6-hydroxydopamine-induced cell death, 7 12 showed potent activities with EC50 values 10.5 10.2 μM, respectively.
Lipocalin-2 (LCN2) is an acute-phase protein that could mediate neuroinflammation after brain injury. We aimed to evaluate if LCN2 level was associated with early neurological deterioration (END) in acute ischemic stroke patients, thus hindering clinical recovery.We conducted a prospective study of patients between June 2021 and February 2022. Serum concentration measured admission using enzyme-linked immunosorbent assay. Outcomes included END 90-day poor functional outcome (modified Rankin...
Stem cell survival after transplantation determines the efficiency of stem treatment, which develops as a novel potential therapy for several central nervous system (CNS) diseases in recent decades. The engrafted cells face damage oxidative stress, inflammation, and immune response at lesion point host. Among damaging pathologies, stress directs to apoptosis even death through signalling pathways DNA damage. However, in‐detail mechanism from has not been revealed clearly. Here, this study,...
Background Bronchopneumonia is a disease of the respiratory tract. It leads to other complications and endangers life health. Long non-coding RNA (lncRNA) participates in occurrence development bronchopneumonia. Nuclear paraspeckle assembly transcript 1 (NEAT1) plays key role inflammatory diseases, but function NEAT1 bronchopneumonia remains unclear.Methods RT-qPCR Western blotting were performed determine genes proteins expressions. MTT was applied test cell viability. Cell apoptosis...
To the editor: Merkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of skin. It occurs more frequently in elderly and immunosuppresed individuals with a male predominance.1 polyomavirus (MCPyV) has been recently associated MCC, which was described as one 7 known human oncogenic viruses.2 MCC characterized by early rapid metastases, although there are some reported cases spontaneous regression.3 Mohs micrographic surgery should be considered for treatment MCC....
Remote sensing of wetlands is one important aspect in application and research remote sensing. This paper studied the HJ-1 CCD data (30m/pixel) applied to wetland resource analysis Yancheng national natural reserve. And we gave evaluation on ability classification. Firstly, spectral typical types. The extraction experiments were carried out by supervised unsupervised classification methods. Finally, compared results with those gained from Landsat-5 TM (June 2007). It indicates that have good...