- Nanoplatforms for cancer theranostics
- Luminescence and Fluorescent Materials
- Advanced biosensing and bioanalysis techniques
- Advanced Nanomaterials in Catalysis
- RNA Interference and Gene Delivery
- Molecular Sensors and Ion Detection
- Nanoparticle-Based Drug Delivery
- Advanced Polymer Synthesis and Characterization
- Metamaterials and Metasurfaces Applications
- Metal-Organic Frameworks: Synthesis and Applications
- Electrospun Nanofibers in Biomedical Applications
- Luminescence Properties of Advanced Materials
- Graphene and Nanomaterials Applications
- Covalent Organic Framework Applications
- Carbon and Quantum Dots Applications
- Supramolecular Self-Assembly in Materials
- Chemical Synthesis and Analysis
- Cancer-related molecular mechanisms research
- Ubiquitin and proteasome pathways
- Advanced Fluorescence Microscopy Techniques
- Advanced Cellulose Research Studies
- Advancements in Solid Oxide Fuel Cells
- biodegradable polymer synthesis and properties
- Extracellular vesicles in disease
- Lipid Membrane Structure and Behavior
Sichuan University
2021-2025
Nanjing Medical University
2025
Yangzhou University
2025
Liaoning University
2025
Lanzhou University
2022-2024
Shandong Institute of Business and Technology
2024
University of Helsinki
2019-2024
Anqing Normal University
2024
Tiangong University
2023-2024
Shenzhen University
2020-2024
Biocompatible fluorescent organic nanoparticles with tunable photoluminescence were prepared via the one-pot oxidation of polydopamine and subsequently utilized for cell imaging.
We report an improved Hummers method for synthesizing graphene quantum dots (GQDs) by directly oxidizing and etching graphite powders. The yield of GQDs is as high 63 ± 7% (by weight, wt%), suggesting this technique suitable producing on a large scale. are nanocrystals with lateral dimensions in the range 2-4 nm average thickness around 1.3 nm. emission peaks as-prepared can be tuned 440 to 510 varying reaction conditions. Their fluorescence yields were tested 1%, which could further...
Water soluble and biocompatible fluorescent organic nanoparticles based on aggregation-induced emission (AIE) material were facilely prepared by mixing AIE surfactant. The utilization of such for cell imaging applications was further explored.
Polyoxometalates are an emerging class of molecular clusters, with well-defined structures and chemical compositions that produced through simple, low-cost, highly reproducible methods. In particular, the wheel-shaped cluster {Mo
Abstract Myocardial infarction (MI) is a critical global health challenge, with current treatments limited by the complex MI microenvironment, particularly excessive oxidative stress and intense inflammatory responses that exacerbate cardiac dysfunction progression. Herein, mannan‐based nanomedicine, Que@MOF/Man, developed to target infarcted heart deliver antioxidative anti‐inflammatory agent quercetin (Que), thereby facilitating beneficial myocardial microenvironment for repair. The...
Aggregation-induced emission (AIE) materials were facilely incorporated into mesoporous silica nanoparticles (MSNs) via one-pot surfactant templated method. Cell imaging and cancer therapy applications of such fluorescent MSNs further explored. We demonstrated that AIE-MSN nanocomposites showed strong fluorescence uniform morphology, making them promising for both cell therapy.
Effective dispersion of nanodiamond (ND) in aqueous media especially the physiological solution is significant importance for its biomedical applications. Herein, effect surfactants on water dispersibility ND were investigated. On basis results, biocompatibility as well utilization zwitterionic surfactant (lecithin) dispersed intracellular delivery doxorubicin hydrochloride explored. We demonstrated that nanoparticles displayed enhanced both and present lecithin. Given facile, effective...
The biomedical applications of aniline oligomers and their derivatives have attracted increasing interest due to electroactive biodegradable properties. However, no reports systematically examined the toxicity these materials, which has severely hindered applications. In this work, cellular responses including dimer, trimer tetramer mouse embryo fibroblast (NIH-3T3) cells adenocarcinomic human alveolar basal epithelial (A549) were determined compared for first time. Our results demonstrated...
Water-dispersible hydrophilic fluoridated HAp:Ln3+ (Ln = Eu or Tb) nanoparticles were prepared via hydrophobic/hydrophilic transformation with surfactants (Pluronic F127). The unique luminescent properties and excellent biocompatibility are promising for cell imaging applications.
Simple dip-coating transforms thermally responsive shape memory polymers into photo-responsive materials and allows for engineering surface functionalization.
The emergence of the deep convolutional neural network (CNN) greatly improves quality computer-aided supporting systems. However, due to challenges generating reliable and timely results, clinical adoption diagnosis systems is still limited. Recent informatics research indicates that machine learning algorithms need be combined with sufficient expertise in order achieve an optimal result. In this research, we used help diagnose four common cutaneous diseases based on dermoscopic images....
The Ugi reaction has been utilized as a new click to synthesize middle-functional copolymers.
A plant-derived compound may treat patients with diseases caused by Gα mutations.
Environmentally benign and biodegradable chitosan (CS) membranes have disadvantages such as low mechanical strength, high brittleness, poor heat resistance water resistance, which limit their applications. In this paper, home-made cellulose nanocrystals (CNC) were added to CS prepare CNC/CS composite through mixing solution casting approaches. The effects of CNC dispersion patterns contents on the properties studied. analysis surface cross-section morphology showed that performance membrane...
As a result of the deficient tumor-specific antigens, potential off-target effect, and influence protein corona, metal-organic framework nanoparticles have inadequate accumulation in tumor tissues, limiting their therapeutic effects. In this work, pH-responsive linker (L) is prepared by covalently modifying oleylamine (OA) with 3-(bromomethyl)-4-methyl-2,5-furandione (MMfu) poly(ethylene glycol) (PEG). Then, L embedded into solid lipid nanoshell to coat apilimod (Ap)-loaded zeolitic...
Covalent organic frameworks (COFs) usually have weak emission because of π–π stacking between layers, linkage bond rotation, or photoinduced electron transfer (PET) monomer parts, which gives a chance to prepare "off–on" fluorescent sensors based on these weakly emissive COFs. Here, nitrogen-doped carbon dots (NCDs) encapsulated in COFTAPT-TT (NCCOFTAPT-TT) are successfully prepared by one-pot method, is synthesized ammonaldehyde condensation 2,4,6-tris(4-aminophenyl)-1,3,5-triazine (TAPT)...