A5100746055- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Osteoarthritis Treatment and Mechanisms
- Tendon Structure and Treatment
- Orthopedic Infections and Treatments
- Foot and Ankle Surgery
- Knee injuries and reconstruction techniques
- Musculoskeletal synovial abnormalities and treatments
- Sports injuries and prevention
- Periodontal Regeneration and Treatments
- Shoulder Injury and Treatment
- Infectious Diseases and Tuberculosis
- Hip disorders and treatments
- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- Spinal Fractures and Fixation Techniques
- Hip and Femur Fractures
- Diabetic Foot Ulcer Assessment and Management
- Spine and Intervertebral Disc Pathology
- Cell Adhesion Molecules Research
- Anatomy and Medical Technology
- Pelvic and Acetabular Injuries
- Cancer-related molecular mechanisms research
- Cervical and Thoracic Myelopathy
- Reconstructive Surgery and Microvascular Techniques
Army Medical University
2015-2024
Chongqing Medical University
2024
Second Hospital of Anhui Medical University
2024
Anhui Medical University
2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024
Anhui Provincial Hospital
2024
University of Science and Technology of China
2024
Yichang Central People's Hospital
2024
China Three Gorges University
2024
Southwest Medical University
2024
This study aimed to calculate the flexion-extension axis (FEA) of knee through in-vivo kinematics data, and then compare it with two major anatomical axes femoral condyles: transepicondylar (TEA) defined by connecting medial sulcus lateral prominence, cylinder (CA) centers posterior condyles.The data 20 healthy subjects were acquired under weight-bearing condition using bi-planar x-ray imaging 3D-2D registration techniques. By tracking vertical coordinate change all points on surface femur...
Tissue cells sense and respond to differences in substrate stiffness. In chondrocytes, it has been shown that stiffness regulates cell spreading, proliferation, chondrogenic gene expression, TGF-β signaling. But how the together with soluble factors influences mechanical properties of chondrocyte is still unclear. this study, we cultured goat articular chondrocytes on polyacrylamide gels 1, 11, 90 kPa (Young's modulus), measured cellular stiffness, traction force, response stretch presence...
Interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) are major proinflammatory cytokines involved in osteoarthritis (OA). These disturb chondrocyte metabolism by suppressing the synthesis of extracellular matrix proteins stimulating release catabolic proteases, but little is known about their role mechanics. Thus, aim this study was to measure effects IL-1β TNF-α on mechanical properties chondrocytes. Chondrocytes from goat knee joints were cultured 96-well plates. The cellular...
Ankle arthrodesis is considered by many to be the standard operative treatment for end-stage ankle arthritis. The purpose of this study was perform a new technique joint surface and determine outcome union rates arthroscopic arthrodesis. A total 68 patients with posttraumatic arthritis, primary osteoarthritis, rheumatoid arthritis were treated between May 2007 December 2012. Our surgical indication deformity less than 15° measured weight-bearing radiographs. Firstly, remaining articular...
The management of tendon tissue injury presents a significant clinical challenge due to the unique properties tendons. Cell-based therapy provides new alternative for regenerating functional tendons, such as in rupture repair, but largely remains at preclinical research stage. A cell source graft preparation is essential successful clinic application. In this study, novel coculture system bone marrow mesenchymal stem cells (BMSCs) and tendon-derived (TDSCs) was developed investigated. BMSCs...
Background. Chronic Achilles tendon rupture is usually misdiagnosed and treated improperly. This study aims to better understand the treatment of chronic rupture. Methods. Patients who were not able perform a single-limb heel rise chosen. Pre- postoperative magnetic resonance imaging (MRI) conducted. By evaluating presence or absence stumps gap length rupture, V-Y advancement, gastrocnemius fascial turndown flap, flexor halluces longus transfer selected for repair. The function ankle foot...
Objective To evaluate the surgical results of V‐Y tendon plasty in treatment chronic Achilles rupture during medium and long‐term follow‐up. Methods Between June 2005 September 2017, 20 patients with underwent our hospital. The mean injury‐to‐surgery time was 20.4 weeks (range, 4–96 weeks). Matles test an improved Thompson used to examine rupture. These were not able stand on tiptoes injured lower extremity. X‐ray tests ruled out chance fracture Kager triangle. MRI confirm final diagnosis....
The repair of porcine articular cartilage defects by using particulated juvenile allograft (PJAC) has demonstrated good short-term clinical efficacy, but the process and mechanism have not been fully elucidated.To study efficacy PJAC in repairing full-thickness to provide an experimental basis for its application.Controlled laboratory study.Thirty Guizhou minipigs were randomly divided into group control group. An 8-mm cylindrical defect was created femoral trochlea either knee all minipigs....
Achilles tendon ruptures are difficult to repair, and the healing rate is low due this structure's anatomic physiological characteristics. It essential develop new techniques increase decrease of complications.To propose evaluate a percutaneous method repairing fresh closed by Kessler's suture under arthroscopy.Case series; Level evidence, 4.Twenty patients were followed at least 12 months in study. First, torn ends debrided during arthroscopy. Then repair was performed using an inside-out...
Objective Mesenchymal progenitor cells (MPCs) are found in articular cartilage from normal controls and patients with osteoarthritis (OA). Nevertheless, the molecular mechanisms of proliferation differentiation these remain unclear. In this study, we aimed to determine involvement Wnt/β-catenin signaling regulating MPCs. Methods MPCs were isolated OA patients. Cells sorted by immunomagnetic cell separation. Cell capacity was evaluated using MTT assay. Toluidine blue staining immunostaining...
Intra-articular injection of mesenchymal stem cells (MSCs) is a promising strategy for osteoarthritis (OA) treatment. However, more and studies reveal that the injected MSCs have poor adhesion, migration, survival in joint cavity. A recent study shows tropoelastin (TE) regulates proliferation phenotypic maintenance as soluble additive, indicating TE could promote MSCs-homing regenerative medicine. In this study, we used medium, compared it with classic media intra-articular such normal...
Purpose: Three-dimensional (3D) printing technology has emerged as a new treatment method due to its precision and personalization. This study aims explore the application of 3D-printed personalized porous tantalum cone for reconstructing bone defect in total knee arthroplasty (TKA) revision. Methods : Between November 2017 October 2020, six patients underwent reconstruction using cones TKA The function was assessed Hospital Special Surgery (HSS) score pre- postoperatively. pain measured by...
Arthroscopic microfracture is a conventional form of treatment for patients with osteochondritis the talus, involving an area < 1.5 cm2. However, some have persistent pain and limitation movement in early postoperative period. No studies investigated combined shortwave these patients. The aim this prospective single-centre, randomized, double-blind, placebo-controlled trial was to compare outcome treated arthroscopic radial extracorporeal shockwave therapy (rESWT) alone, ostechondritis...
Objective To explore the feasibility of 3D printed customized guides assisting precise drilling Kirschner wires in subtalar joint arthrodesis. Methods We retrospectively reviewed data 29 patients (30 joints) who underwent arthrodesis between 1 July 2013 and 31 December 2017. The were designed on a full‐scale polylactic acid model made from computed tomography (CT) by Model Intestinal Microflora Computer Simulation (MIMICS) software, which manufactured printing technology. A total 14 joints...
Surgical excision is the traditional treatment for osteoid osteoma. However, complexity of foot anatomy makes a satisfactory outcome challenging. Difficulty in localizing lesion intraoperatively may result either incomplete tumor resection or excessive bone loss. To date, no published report has described use three-dimensional printing surgical osteoma calcaneus. In this case, we printed model calcaneus 17-year-old female patient with 2-year history night pain lateral aspect hindfoot and...
To accurately drill the Kirschner wire with help of 3D-printed personalized guide and to evaluate feasibility 3D technology as well outcome surgery.Patients' DICM data ankle via CT examinations were introduced into MIMICS software design guides. Two 2mm wires drilled guides; C-arm fluoroscopy was used confirm position before applying cannulated screws. The patients who underwent arthrodesis divided two groups. experimental group adopted guides, while control received traditional method,...
Ankle osteoarthritis (OA) is an important factor that causes pain and dysfunction after ankle joint movement. In early mid-term OA, supramalleolar osteotomy can delay the progression of disease maximize preservation function. Three-dimensional printing (3DP) technology has brought us new hope, which improve accuracy osteotomy, reduce number fluoroscopy, amount blood loss, achieve personalized accurate treatment. The data 16 patients with OA in our center from January 2003 to July 2020 were...