- Thyroid Cancer Diagnosis and Treatment
- Sinusitis and nasal conditions
- Allergic Rhinitis and Sensitization
- Nasal Surgery and Airway Studies
- Oral and Maxillofacial Pathology
- Lymphoma Diagnosis and Treatment
- Cancer-related Molecular Pathways
- Thyroid and Parathyroid Surgery
- Neuroendocrine Tumor Research Advances
- T-cell and Retrovirus Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Breast Lesions and Carcinomas
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Ear and Head Tumors
- Head and Neck Anomalies
- Histone Deacetylase Inhibitors Research
- Pharmaceutical studies and practices
- Soft tissue tumor case studies
- Venous Thromboembolism Diagnosis and Management
- Vasculitis and related conditions
- Nasolacrimal Duct Obstruction Treatments
- Hydrocarbon exploration and reservoir analysis
- interferon and immune responses
Capital Medical University
2018-2024
Beijing Friendship Hospital
2019-2024
Soochow University
2024
First Affiliated Hospital of Soochow University
2024
Sichuan University
2021-2024
West China Hospital of Sichuan University
2023-2024
Jiangsu Provincial Hospital of Traditional Chinese Medicine
2023
Nanchang University
2019-2020
First Affiliated Hospital of Nanchang University
2019-2020
Sun Yat-sen University
2019
Background: Although papillary thyroid microcarcinoma (PTMC) has a high incidence and excellent clinical outcome, debate continues as to the therapeutic approach that would be most appropriate after confirming diagnosis.Methods: We retrospectively analyzed medical records of 311 patients with T1aN0M0 PTMC between January 2013 September 2018. In all, 168 underwent microwave ablation (MWA), 143 surgery. MWA was performed using extensive hydrodissection. The surgery comprised lobectomy (TL)...
Abstract Increasing evidence suggests that intratumoral microbiota plays a pivotal role in tumor progression, immunosurveillance, metastasis, and chemosensitivity. Particularly, pancreatic ductal adenocarcinoma, tumor‐resident Gammaproteobacteria could transform the chemotherapeutic drug gemcitabine (Gem) into its inactive form, thus rendering chemotherapy ineffective. Herein, strategy for selectively eradicating bacteria was described overcoming Gem resistance cancer animal model. An...
Background The optimal treatment method for papillary thyroid microcarcinoma (PTMC) is lacking consensus. Here we aimed to compare the efficacy and safety of surgery microwave ablation (MWA) PTMC.Methods clinical data 644 patients with PTMC treated between July 2013 June 2020 were retrospectively analyzed. A total 320 324 underwent MWA surgery, respectively. We observed lesion changes in group compared recurrence, metastasis, complications, other health economic indicators 2 groups.Results...
Background Preoperative assessment of follicular thyroid neoplasms is challenging using the current US risk stratification systems (RSSs) that are applicable to papillary neoplasms. Purpose To develop a feature-based RSS for differentiating between adenoma (FTA) and carcinoma (FTC) in biopsy-proven neoplasm compare it with existing RSSs. Materials Methods This retrospective multicenter study included consecutive adult patients who underwent conventional received final diagnosis from seven...
// Peipei Yang 1, * , Weicai Chen Xuhui Li 2 Grant Eilers 3 Quan He 1 Lili Liu Yeqing Wu Yuehong Wei Yu Jonathan A. Fletcher Wen-Bin Ou 2, Zhejiang Provincial Key Laboratory of Silkworm Bioreactor and Biomedicine, College Life Sciences, Sci-Tech University, Hangzhou, China Applied Enzymology, Yangtze Delta Region Institute Tsinghua Jiaxing, Zhejiang, Department Pathology, Brigham Women's Hospital Harvard Medical School, Boston, MA, USA These authors contributed equally to this work...
Summary We conducted a retrospective, multicentre study to compare consolidation therapy with or without first‐line autologous stem cell transplant (ASCT) for peripheral T‐cell lymphoma (PTCL) patients in real‐world setting. enrolled 347 PTCL who achieved complete response after treatment. Of these, 257 received chemotherapy (non‐ASCT group) and 90 ASCT (ASCT group). Clinical outcomes were comparable between non‐ASCT groups. After propensity score matching, the 2‐year cumulative incidence of...
Pancreatic ductal adenocarcinoma (PDAC) poses a challenge in oncology due to its high lethality and resistance immunotherapy. Recently, emerging research on the stimulator of interferon gene (STING) pathway offers novel opportunities for Although STING expression is retained PDAC cells, response cells agonists remains ineffective. Signal transducer activator transcription 3 (STAT3), downstream STING, notably overexpressed pancreatic cancer related tumor survival immune escape. We observed...
Lymphoma-associated venous thromboembolism (VTE) can be a serious complication in lymphoma patients. We designed nomogram as guide to estimate the VTE risk retrospectively analyzed 555 Chinese patients who were newly diagnosed at West China Hospital. The was generated based on multivariate regression coefficients. analysis indicated that advanced clinical stage (p < .001*), Hodgkin = .045*), and prechemotherapy Hb level <115 g/L .01*) independent factors for A calibration plot area under...
This study was performed to investigate the accuracy of conventional ultrasound (US), contrast-enhanced US (CEUS), and dynamic magnetic resonance imaging (DCE-MRI) in assessing size breast cancer.In total, 49 cancer lesions 48 patients were included this study. The inclusion criteria performance total mastectomy or breast-conserving surgery for treatment our hospital from January 2017 December 2020 with complete pathological results, as well US, CEUS, DCE-MRI examinations results. exclusion...
The objective of this study is to develop a gene signature related the immune system that can be used create personalized immunotherapy for Uterine Corpus Endometrial Carcinoma (UCEC). To classify UCEC samples into different clusters, we utilized consensus clustering analysis. Additionally, correlation algorithms were employed investigate tumor microenvironment (TIME) in diverse clusters. explore biological function, conducted GSEA Next, developed Nomogram by integrating prognostic model...
There is a consensus that central compartment lymph node dissection or modified radical lateral neck should be performed in papillary thyroid microcarcinoma (PTMC) patients with metastases. Prophylactic (PCLND) clinically node-negative (cN0) PTMC to reduce locoregional recurrence (LRR) rate and improve prognosis remains controversial. The present study aimed analyze the effect of PCLND on LRR postoperative complications cN0 patients. We reviewed cohort who underwent surgery between January...
The negative effects of hepatic inflow occlusion (HIO) on postoperative liver function patients with hepatocellular carcinoma (HCC) after resection have been reported. Nevertheless, whether or not HIO could influence the long-term outcomes remains unclear.A total 396 were included in this study and divided into without (WO) group (N.=112) (N.=284). Aiming to minimize selection bias confounding variables, we used propensity score matching (PSM) a 0.2 caliper balance baseline variables....
To compare and study the decoction dissolution of active constituents in crude processed Corni Fructus. HPLC, traditional Chinese medicine (TCM) method methods were adopted to yield rate loganin morroniside, The results showed that content morroniside Fructus did not change significantly; compared with Fructus, (decoction) contained much higher loganin, no obvious morroniside; (extracts) significant difference dissolution, but notable increase intestinal fluid; gastric fluid, dissolutions....
To establish a risk prediction model for postoperative control of chronic sinusitis with nasal polyps.
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a highly heterogeneous disease varied clinical features and treatment effects. This study aimed to investigate the additive effect of blood tissue eosinophilia on patients CRSwNP.