A5003338017- Nerve injury and regeneration
- Adipose Tissue and Metabolism
- Eicosanoids and Hypertension Pharmacology
- Mesenchymal stem cell research
- Inflammatory mediators and NSAID effects
- Peroxisome Proliferator-Activated Receptors
- Adipokines, Inflammation, and Metabolic Diseases
- Neurological disorders and treatments
- Stress Responses and Cortisol
- RNA Research and Splicing
- Neuroendocrine regulation and behavior
- Advanced Glycation End Products research
- Liver Disease Diagnosis and Treatment
- Cognitive Abilities and Testing
- RNA regulation and disease
- Coronary Artery Anomalies
- Nasal Surgery and Airway Studies
- Biochemical effects in animals
- Cardiac Ischemia and Reperfusion
- Blood Coagulation and Thrombosis Mechanisms
- Natural Antidiabetic Agents Studies
- Gout, Hyperuricemia, Uric Acid
- Inflammatory Myopathies and Dermatomyositis
- Heart Failure Treatment and Management
- Sirtuins and Resveratrol in Medicine
Suez Canal University
2006-2024
Injury of a peripheral nerve (PNI) leads to both ischemic and inflammatory alterations. Sciatic injury (SNI) represents the most widely used model for PNI. Mesenchymal stem cell-based therapy (MSCs) has convenient properties on PNI by stimulating regeneration. Melatonin cytoprotective activity. The neuroprotective characteristics MSCs melatonin separately or in combination remain knowledge need. In rats-challenged SNI, therapeutic roles intralesional intraperitoneal injections were evaluated...
Drug claims databases are increasingly available and provide opportunities to investigate epidemiologic questions. The authors used computerized drug from a social security system in 5 French districts predict the probability that person had Parkinson's disease (PD) based on patterns of antiparkinsonian (APD) use. Clinical information for population-based sample persons using APDs 2007 was collected. built prediction model demographic variables as predictors investigated additional...
The epidemic of metabolic syndrome is increasing worldwide and correlates with elevation in serum uric acid marked increase total fructose intake. Fructose raises the latter inhibits nitric oxide bioavailability. We hypothesized that fructose-induced hyperuricemia may have a pathogenic role treatment or increased improve it.Two experiments were performed. Male Sprague-Dawley rats fed control diet high-fructose to induce syndrome. received either sodium nitrate allopurinol for 10 weeks...
Angiogenesis is regulated in a tissue-specific manner all patients, especially those with diabetes. In this study, we describe novel molecular pathway of angiogenesis regulation diabetic rats myocardial infarction (MI) and examine the cardioprotective effects different doses sitagliptin. Male were divided into 5 groups: normal vehicle group, + MI, MI mg/kg sitagliptin, 10 Isoproterenol resulted significant (p < 0.05) disturbance to electrocardiogram, cardiac histopathological manifestations,...
The objective of this study was to investigate whether thrombin activatable fibrinolytic inhibitor (TAFI) Thr325Ile polymorphism and TAFI antigen (Ag) levels could constitute a risk marker myocardial infarction (MI) in Egyptian patients.The included forty-six patients with acute MI (mean age 55.7 +/- 8.1 years, 33 men, 13 women) compared sex-matched healthy volunteers (n = 54) as control group. Clinical examination, laboratory investigations, electrocardiography (ECG) and/or echocardiography...
Aims. Neuropathic pain following nerve injury does not respond well to most available pharmacological remedies. We aimed compare the outcome of addition adipose-derived mesenchymal stem cells (ADMSCs) pregabalin for neuropathic treatment. Methods. Adult female albino rats ( <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1"> <mi>n</mi> <mo>=</mo> <mn>100</mn> </math> ) were randomized receive traumatic sciatic or sham. Animals then ADMSC treatment with without pregabalin. conducted a...
Objective This work aimed to study the effect of low intensity electrical stimulation and Mesenchymal stem cells transplantation on repair sciatic nerve crush injury. Background Injury peripheral nerves results in temporary or life-long neuronal dysfunction that can subsequently lead economic social disability. Despite early diagnosis use modern surgical techniques, functional recovery never reach pre-injury level. Several alternate approaches have been proposed get beneficial effects...
Aim: The aim of this study is to estimate the prevalence albuminuria in type II diabetes mellitus and report its influence, as a risk factor, for presence severity diabetic retinopathy (DR). Subjects Methods: During period January 2012 May 2013, 420 patients were examined. Albuminuria adjusted creatinine concentration was measured. Body mass index hemoglobin A1c also Patients evaluated by direct indirect ophthalmoscopy classified non-retinopathy, non-proliferative, proliferative or...
Peripheral nerve injuries (PNI) are a frequent and disabling condition which affects 13 to 23 per 100,000 persons each; it remains major cause of morbidity social disruption. The aim this study is evaluate the possible therapeutic potency melatonin (100 mg/kg) or resveratrol in enhancing recovery after Schwann cells transplantation injured sciatic nerves albino rats an attempt overcome multiple factors that limit axons growth injury. Recovery function was analyzed by biochemical...
Introduction: There is debate on the predictive usefulness of electrocorticography (ECoG) during anterior temporal lobectomy (ATL) in lobe epilepsy (TLE) patients. The purpose this study was to determine quantitative intraoperative ECoG monitoring for postoperative seizure outcomes after ATL TLE Methods: enrolled thirteen patients who underwent ECoG-assisted ATL. Pre- and post-resection spike frequency (/min) amplitude (μv/mm) were analyzed with histopathological preoperative...
Ebsteins anomaly (EA) is a rare congenital heart disease which occurs in approximately 1 200,000 live births and represents less than 1% of all cases disease(1). AE cardiopathy the right ventricle that originates an embryological peculiarity tricuspid valve responsible for over-apical implantation septal leaflet (2). We report case 47-year-old patient with asymptomatic EA, admitted junctional tachycardiaat 200bpm haemodynamic instability. Due to this instability, we administred synchronous...
Background: Fatigue is a core symptom of idiopathic inflammatory myopathies (IIM) and impacts on quality life more than any other common according to findings from our past research project. Due the subjective nature fatigue lack evidence-based therapies currently available, often overlooked. Generic questionnaires such as FACIT-F show good reliability validity, however, disease-specific tools are not available. The purpose this study explore symptoms with patients beyond confines generic...
This study was conducted to compare between the possible effects of rosiglitazone A new oral antidiabetic drug with selective PPAR-gamma agonistic effect in a dose 0.03 mg/kg BW and gliclazide An sulphonylurea 10 either used alone or combination, for 6 weeks on liver, serum glucose lipid profile streptozotocin diabetic rats. Thirty rats were randomized into 5 groups (n=6). Group I; control group given saline orally daily weeks. II; induced group. III received rosiglitazone, while IV V...
Background: Researches revealed that increased levels of stress hormones lead to enhancement memory consolidation in rodents. Recently, it became apparent the brain oscillations reflect cognitive aspects and information processing brain. Quantitative electroencephalogram (qEEG) provides an objective assessment electrical activity via many techniques such as power spectral analysis coherence. Aim: To assess effect gender on qEEG during delayed retrieval after exposure acute stress. Subjects...
Acoustic Rhinometry (AR) measures the relationship of cross-sectional area and distance into nasal cavity.Great efforts have been done to validate standardize its clinical use.Inspite many researches in Egypt by AR, there are no normal National Egyptian Physiological gold standards MCA, DMCA NCV like other countries.This study was carried out establish local reference values for AR parameters healthy adults.One hundred thirty volunteer students Faculty Medicine, Suez Canal University age...
Results: Heart rate was 71±7 bpm before and 72±8 after apnoea (change: +3±13%, p=NS).Systolic diastolic BP were 123±12 mm Hg 78±7 before, 118±15 (-4±9%, p=NS) 78±10 (+1±14%, apnoea.Main echocardiographic findings are reported in table underneath.Conclusions: Findings from the present study suggest that breath-hold submersion professional sea-divers induces mild but statistically significant dilatation of left ventricle with weak reduction systolic diameter, likely due to increased...
This study was conducted to compare between the possible effects of rosiglitazone "A new oral antidiabetic drug with selective PPAR-gamma agonistic effect" in a dose 0.03 mg/kg BW and gliclazide " An sulphonylurea" 10 either used alone or combination, for 6 weeks on liver, serum glucose lipid profile streptozotocin diabetic rats.