A5085287368- Advanced Radiotherapy Techniques
- Endometrial and Cervical Cancer Treatments
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Medical Imaging Techniques and Applications
- Management of metastatic bone disease
- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- Lung Cancer Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Advances in Oncology and Radiotherapy
- Hepatocellular Carcinoma Treatment and Prognosis
- Sarcoma Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Advanced MRI Techniques and Applications
- Meningioma and schwannoma management
- Head and Neck Cancer Studies
- Cervical Cancer and HPV Research
- Effects of Radiation Exposure
- Radiation Dose and Imaging
- Breast Cancer Treatment Studies
- Uterine Myomas and Treatments
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
University of Washington
2015-2025
Michigan State University
2022-2024
Seattle University
2019-2021
University of Washington Medical Center
2013-2020
Medline (United States)
2020
Sunnybrook Health Science Centre
2019
University of Toronto
2019
Neurological Surgery
2019
University of Southern California
2019
Princess Alexandra Hospital
2019
To develop recommendations for management of patients with breast cancer (BC) germline mutations in BC susceptibility genes.The American Society Clinical Oncology, Radiation and Surgical Oncology convened an Expert Panel to based on a systematic review the literature formal consensus process.Fifty-eight articles met eligibility criteria formed evidentiary basis local therapy recommendations; six randomized controlled trials systemic criteria.Patients newly diagnosed BRCA1/2 may be considered...
Dynamic contrast-enhanced magnetic resonance imaging (DCE MRI) is a method of the physiology microcirculation. A series recent clinical studies have shown that DCE MRI can measure and predict tumor response to therapy. Recent advances in MR technology provide enhanced spatial temporal resolution allow application this methodology management cancer patients. The September issue journal provided microcirculation section update readers on exciting challenging topic. Evidence mounting MRI-based...
A generalized mathematical model for the relation between radiation dose and tumor cell death enables better treatment planning schedule designs current targeted high-dose therapies in cancer.
Background Robust approaches to quantify tumor heterogeneity are needed provide early decision support for precise individualized therapy. Purpose To conduct a technical exploration of longitudinal changes in patterns on dynamic contrast‐enhanced (DCE) magnetic resonance imaging (MRI), diffusion‐weighted (DWI) and FDG positron emission tomography / computed (PET/CT), their association radiation therapy (RT) response cervical cancer. Study Type Prospective observational study with MRI PET/CT...
Treatment decisions for multimodal therapy in soft tissue sarcoma (STS) patients greatly depend on the differentiation between low-grade and high-grade tumors. We developed MRI-based radiomics grading models (G1) (G2/G3) STS.The study was registered at ClinicalTrials.gov (number NCT03798795). Contrast-enhanced T1-weighted fat saturated (T1FSGd), fat-saturated T2-weighted (T2FS) MRI sequences, tumor following French Federation of Cancer Centers Sarcoma Group obtained from pre-therapeutic...
The concept of spatially fractionated radiation therapy (SFRT) was conceived over 100 years ago, first in the form GRID, which has been applied to clinical practice since its early inception and continued present even with markedly improved instrumentation therapy. LATTICE (LRT) introduced 2010 as a conceptual 3D extension GRID several uniquely different features. Since 2014, when patient treated, 150 patients bulky tumors worldwide have received LRT. Through brief review basic principles...
Background. A commonly held belief is that patients with collagen vascular diseases (CVD) have a greater risk of radiation therapy complications than without CVD. This impression based on anecdotal reports, however. Methods. group 61 CVD were compared matched control The included 39 rheumatoid arthritis (RA), 13 systemic lupus erythematosus (SLE), 4 sclerosis (scleroderma) (SSc), dermatomyositis, and 1 polymyositis. was respect to age, sex, tumor site histologic characteristics, treatment...
The purpose of this study was to assess heterogeneity tumor microcirculation determined by dynamic contrast-enhanced magnetic resonance (MR) imaging and its prognostic value for radiosensitivity long-term control using pixel-by-pixel analysis the contrast enhancement. Sixteen patients with advanced cervical cancer were examined MR at time radiation therapy. Pixel-by-pixel statistical ratio post- precontrast relative signal intensity (RSI) values in region performed generate pixel RSI...
From 1965 to 1997, 49 patients were diagnosed and treated for intracranial ependymoma at one institution. Tumor location was infratentorial in two thirds, pathology low grade 38 (78%). Gross total resection of the primary tumor achieved 21 (43%). Thirty-six received adjuvant radiotherapy; entire neuraxis 14, whole brain 10, local field only 12. Median follow-up 9.6 years (range, 2-33 years). The 5-, 10-, 15-year overall survival rates 71.4%, 63.5%, 63.5% craniospinal radiotherapy, 60.0%,...
Abstract Applications of mathematical modeling can improve outcome predictions cancer therapy. Here we present a kinetic model incorporating effects radiosensitivity, tumor repopulation, and dead-cell resolving on the analysis volume regression data 80 cervical patients (stages 1B2-IVA) who underwent radiation Regression rates derived parameters correlated significantly with clinical (P < 0.001; median follow-up: 6.2 years). The 6-year local control rate was 87% versus 54% using...