A5101445923- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Lung Cancer Treatments and Mutations
- Retinal Diseases and Treatments
- Traditional Chinese Medicine Analysis
- Metabolomics and Mass Spectrometry Studies
- Lung Cancer Diagnosis and Treatment
- Cancer Mechanisms and Therapy
- Ocular Surface and Contact Lens
- Hernia repair and management
- Lung Cancer Research Studies
- Traditional Chinese Medicine Studies
- Salivary Gland Disorders and Functions
- Single-cell and spatial transcriptomics
- Thermal Regulation in Medicine
- Gout, Hyperuricemia, Uric Acid
- Mycobacterium research and diagnosis
- Asthma and respiratory diseases
- Pancreatitis Pathology and Treatment
- Ion Channels and Receptors
- Synthesis of β-Lactam Compounds
- Ureteral procedures and complications
- Synthesis and biological activity
- Breast Implant and Reconstruction
- Quinazolinone synthesis and applications
Minzu University of China
2025
Xiamen University
2019-2025
First People's Hospital of Chongqing
2017-2024
Southern Medical University
2015-2024
Guangdong Academy of Medical Sciences
2024
Guangdong Provincial People's Hospital
2024
Eye Center
2021-2024
Chongqing University
2024
Shenzhen Luohu People's Hospital
2023
Hubei University of Medicine
2022
// Longmei Cai 1,* , Jinbang Li Xiaona Zhang 1, 4,* Yaoyong Lu 5,* Jianguo Wang 1 Xiaoming Lyu 3 Yuxiang Chen Jinkun Liu 2 Hongbing Ying Xin Cancer Research Institute, Southern Medical University, Guangzhou 510515, China School of Chinese Traditional Medicine, Central Laboratory, The Third Affiliated Hospital, 4 Sixth Hospital Sun Yat-Sen 510655, 5 Department Radiation Oncology, Gaozhou People's 525200, * These authors contributed equally. Correspondence to: Li, e-mail: xinli268@gmail.com...
Papillary thyroid cancer (PTC) is a common malignancy of the endocrine system, and its morbidity mortality are increasing year by year. Traditional two-dimensional culture cell lines lacks tissue structure difficult to reflect heterogeneity tumors. The construction mouse models inefficient time-consuming, which be applied individualized treatment on large scale. Clinically relevant that recapitulate biology their corresponding parental tumors urgently needed. Based clinical specimens PTC, we...
Précis: 240° and 360° goniotomy (GT) demonstrated similar efficacy in intraocular pressure reduction, both outperforming 120°GT juvenile open-angle glaucoma (JOAG) patients at postoperative 6 months follow-up. Purpose: To compare the surgical safety of 120-, 240-, 360-degree for with (JOAG). Patients Methods: This multicenter retrospective study included 102 eyes JOAG patients, who underwent GT a follow up least months. were categorized into three groups: (1) 120°GT, (2) 240°GT, (3) 360°GT....
Purpose.: To monitor the change of suprachoroidal space (SCS) using ultra high resolution-optical coherence tomography (UHR-OCT) following SCS injection with different drug formulations. Methods.: An amount 10 or 20 μL saline indocyanine green (ICG) triamcinolone acetonide (TA) suspension (40 80 mg/mL) was injected suprachoroidally into guinea pig eye a 30-gauge needle. Immediately after injection, eyes were imaged by UHR-OCT from 60 minutes up to 24 hours. At each time point, area on OCT...
Abstract Acute and chronic itch are prevalent incapacitating, yet the neural mechanisms underlying both acute just starting to be unraveled. Activated transcription factor 4 (ATF4) belongs ATF/CREB family primarily participates in regulation of gene transcription. Our previous study has demonstrated that ATF4 is expressed sensory neurons. Nevertheless, role sensation remains poorly understood. Here, we demonstrate plays a significant regulating sensation. The absence dorsal root ganglion...
To compare biometric parameters, especially lens in patients with high myopia and anisometropia.Patients spherical equivalent greater than -6D at least one eye an axial length 26 mm a difference binocular 2 were included this study. In each patient, the relatively shorter was assigned to Group S, other L. whose 4 mm, S1 L1. less S2 L2. Central corneal thickness, curvature radius, length, anterior chamber depth, white-to-white diameter radius of posterior capsules compared between S L, Groups...
Lonicera japonica is not only an important resource of traditional Chinese medicine, but also has very high horticultural value. Studies have been performed on the physiological responses L. leaves to chilling, however, molecular mechanism underlying low temperature-induced morphological changes remains unclear. In this study, it demonstrated that ratio pigments content including anthocyanins, chlorophylls, and carotenoids was significantly altered in response chilling condition, resulting...
The aim of the present study was to observe feasibility and effect cornea slice acquired from femtosecond laser surgery, small incision lenticule extraction (SMILE) as patch graft for prevention drainage tube exposure compare with sclera.The research is a prospective comparative randomized study. Patients who received Ahmed glaucoma valve implantation surgery August 2015 January 2017 at Xiamen Eye Center were randomly divided into 2 groups. Group A (corneal group) included 131 cases (135...
This study investigated the effect of electroacupuncture (EA) on browning white adipose tissue (WAT) via angiogenesis and its potential mechanism in obese mice. Four-week-old male C56BL/6 mice were randomly divided into a high-fat diet (HFD) normal chow (ND) group. After 12 weeks, HFD two groups to receive or not EA for 3 weeks. treatment, body weight, adipocyte size, serum glucose (GLU), triacylglycerol (TG), cholesterol (CHO), leptin (Lep), monocyte chemoattractant protein-1 (MCP-1), WAT...
Thioridazine (THZ) has been identified as a potential regulator of tumour progression, and programmed cell death 4 (PDCD4) reported novel suppressor. This study aimed to investigate the link between PDCD4 THZ in regulation nasopharyngeal cancer (NPC) proliferation. The effect on NPC cells was determined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assays. Then, involvement apoptosis cycle THZ-mediated viability assessed by flow cytometry. Related mRNAs...
Numerous studies have demonstrated the involvement of messenger RNAs (mRNAs) and non-coding RNAs, including long (lncRNA), circular (circRNAs) microRNA (miRNAs), in gouty arthritis onset; however, regulatory mechanism has not yet been elucidated. Here, we applied whole-transcriptome sequencing to identify differentially expressed circRNAs, lncRNAs, miRNAs mRNAs between gout patients normal people, constructed co-regulated networks circRNAs lncRNAs according competitive endogenous RNA (ceRNA)...
Prospective case series.
Abstract Background Network pharmacology is pivotal for the study of mechanism action traditional Chinese medicine (TCM). However, there are currently some challenges in data processing and visualization network (TCMNP). We develop R-environment-based software database package TCMNP. Methods TCMNP designed analysis compositions TCM compounds, herbs, ingredients, corresponding targets pathway enrichment. Data R using “dplyr”, “clusterProfiler”, “ggplot2”, “circlize” packages, as well...
BACKGROUND Liver cancer treatment is characterized by multidisciplinary participation and coexistence of multiple methods. Hypofractionated intensity-modulated radiotherapy a new precise technique applied to the systemic malignant tumors. There lack understanding hypofractionated combined with therapy in metastatic hepatocellular carcinoma (HCC). CASE SUMMARY We report case HCC treated therapy. A 41-year-old man was diagnosed (T3N1M1 stage IVB). Because it found be late had already...