A5028426428- Drug-Induced Adverse Reactions
- Urticaria and Related Conditions
- Autoimmune Bullous Skin Diseases
- Cutaneous Melanoma Detection and Management
- Dermatological and COVID-19 studies
- Cutaneous lymphoproliferative disorders research
- Contact Dermatitis and Allergies
- Dermatology and Skin Diseases
- Nonmelanoma Skin Cancer Studies
- Streptococcal Infections and Treatments
- Telemedicine and Telehealth Implementation
- COVID-19 and healthcare impacts
- Nail Diseases and Treatments
- Genital Health and Disease
- Eosinophilic Disorders and Syndromes
- Dermatological diseases and infestations
- Health Systems, Economic Evaluations, Quality of Life
- Medicine and Dermatology Studies History
- Neurofibromatosis and Schwannoma Cases
- Bone health and osteoporosis research
- Digital Imaging in Medicine
- Autoimmune and Inflammatory Disorders
- Clinical practice guidelines implementation
- Healthcare Systems and Practices
- Estrogen and related hormone effects
Université Paris-Saclay
2021-2025
Inserm
2020-2025
Université Paris-Est Créteil
2014-2025
Assistance Publique – Hôpitaux de Paris
2014-2025
Hôpital Ambroise-Paré
2023-2025
CentraleSupélec
2016-2025
Midwestern University
2025
Laboratoire Vision Action Cognition
2025
Hôpitaux Universitaires Henri-Mondor
2013-2024
Institut Mondor de Recherche Biomédicale
2011-2024
On March 11, 2020, the World Health Organization declared coronavirus disease 2019 (COVID-19) outbreak as a pandemic, with over 720,000 cases reported in more than 203 countries of 31 March. The response strategy included early diagnosis, patient isolation, symptomatic monitoring contacts well suspected and confirmed cases, public health quarantine. In this context, telemedicine, particularly video consultations, has been promoted scaled up to reduce risk transmission, especially United...
Vitamin D deficiency leads to secondary hyperparathyroidism, increased bone turnover, and loss and, when severe, osteomalacia. is common in elderly people, especially the institutionalized. The definition of vitamin hampered by fact that large interlaboratory differences exist assays for serum 25-hydroxyvitamin (25OHD), main circulating metabolite. international Multiple Outcomes Raloxifene Evaluation study, a prospective intervention trial postmenopausal women with osteoporosis, offered...
To the Editor: Coronavirus disease 19 (COVID-19), a pneumonia associated with severe acute respiratory syndrome coronavirus 2 (SARS-Cov2), was first identified in Wuhan, China, December 2019, and characterized as pandemic by World Health Organization on March 11, 2020. Fever, dry cough, dyspnea, fatigue, anorexia, ageusia, anosmia are common symptoms of COVID-19. Reported skin manifestations COVID-19 include erythematous lesions, sometimes dengue-like petechiae,1Joob B. Wiwanitkit V. can...
Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse reaction characterized by rash with sterile pustules, high fever and elevated circulating neutrophil counts.To investigate the frequency clinical features of AGEP systemic involvement.This retrospective study included all patients hospitalized in our department between 2000 2010 discharge diagnosis AGEP. Patients had to fulfil following criteria: (i) specific EuroSCAR score > 4 (ii) biological radiological...
The histopathological features of drug rash with eosinophilia and systemic symptoms (DRESS) syndrome remain poorly characterized.To better characterize the DRESS syndrome, define phenotype effector cells in skin compare it maculopapular (MPR).We conducted a retrospective study on 50 biopsies from patients (n = 36). Histopathological immunophenotypical were studied compared series MPRs 20).Foci interface dermatitis, involving cutaneous adnexae, frequently seen cases DRESS. Eosinophils only...
Journal Article Linear IgA bullous dermatosis: comparison between the drug‐induced and spontaneous forms Get access J. Chanal, Chanal Department of Dermatology Assistance Publique–Hôpitaux de Paris (APHP) Groupe Hospitalier Henri‐Mondor 51 Avenue du Maréchal‐de‐Lattre‐de‐Tassigny 94010 Créteil France Search for other works by this author on: Oxford Academic Google Scholar S. Ingen‐Housz‐Oro, Ingen‐Housz‐Oro Correspondence Saskia Ingen‐Housz‐Oro. E‐mail: saskia.oro@hmn.aphp.fr N. Ortonne,...
Abstract Background Neurofibromatosis 1 (NF1), a common autosomal dominant disorder, was shown in one study to be associated with 15-year decrease life expectancy. However, data on mortality NF1 are limited. Our aim evaluate large retrospective cohort of patients seen France between 1980 and 2006. Methods Consecutive referred the National French Referral Center for Neurofibromatoses were included. The standardized ratio (SMR) its 95% confidence interval (CI) calculated as observed over...
Background: Decreased ability to absorb calcium with age limits adaptation low intake and is thought lead secondary hyperparathyroidism increased risk for hip other fractures. However, the associations between fractional absorption, dietary intake, fracture have never been studied. Objective: To determine whether absorption in women increases subsequent nonspine Design: Prospective cohort study. Setting: Four clinical centers Baltimore County, Maryland; Portland, Oregon; Minneapolis,...
This study examined the effect of time lag on validity retrospective self-reports sexual behavior. Seventy-five heterosexual students (44 women, 31 men) made daily recordings behavior, condom use, and alcohol or substance use for 1 month. Ability respondents to recall behavior recorded during this period was assessed at 1, 2, 3 months after diary completion using interviews (25 interviewed each interval). For vaginal intercourse, total error significantly greater than month post-diary. all...
Toxic epidermal necrolysis (TEN) is a rare drug-related life-threatening acute condition. Sepsis the main cause of mortality. Skin colonization on top impaired barrier function promotes bloodstream infections (BSI). We conducted this study to describe epidemiology, identify early predictors BSI, and assess predictive value for bacteremia routine skin surface cultures. retrospectively analyzed charts all patients with Stevens-Johnson syndrome (SJS) TEN hospitalized over an 11-year period....
Stevens-Johnson syndrome and toxic epidermal necrolysis are severe adverse cutaneous drug reactions characterized by widespread skin mucous membrane detachments, including bronchial mucosa, which may be associated with respiratory failure requiring mechanical ventilation. The presentation outcome of patients ventilation the characteristics epithelial lesions among ventilated reported. Predictors available on hospital admission were identified using univariate multivariate logistic...
Epidermal necrolysis (EN) encompasses Stevens-Johnson syndrome (SJS, < 10% of the skin affected), Lyell (toxic epidermal necrolysis, TEN, with ≥30% affected) and an overlap (10 to 29% affected). These rare diseases are caused, in 85% cases, by pharmacological treatments, symptoms occurring 4 28 days after treatment initiation. Mortality is 20 25% during acute phase, almost all patients display disabling sequelae (mostly ocular impairment psychological distress). The objective this French...
Neurofibromatosis type 1 is fully penetrant by the age of 8 years, and 3 criteria diagnosis are dermatological: café-au-lait spots (CLS), intertriginous freckling neurofibromas (NF).The aim our study was to determine evolving pattern cutaneous manifestations during adulthood.Phenotypic data patients seen in center between March 2003 December 2009 were studied. Patients classified 10-year groups. Following clinical characteristics, number CLS subcutaneous NF compared according age.728...
Skin conditions are a common reason for patients to consult emergency department (ED) physicians.To evaluate real-time teledermatologic expertise with the use of mobile telephones diagnosis and management skin in seen ED.This observational study adults who consecutively consulted ED dermatologic condition was conducted under routine from May 1, 2008, through June 30, 2010.Diagnosis agreement concordance.One hundred eleven were enrolled study. Eighty-three (74.8%) evaluated using...
Ear, nose, and throat (ENT) lesions are frequently involved in Stevens-Johnson syndrome toxic epidermal necrolysis (SJS/TEN), although a detailed description is lacking the literature.To describe ENT at acute stage follow-up large series of patients with SJS/TEN identify factors associated severe form.Retrospective study 49 hospitalized referral care center from 2005 to 2010. Patients who underwent full workup including examination nasal fiberoptic endoscopy by an otorhinolaryngologist phase...
Abstract Background: Over the past few years there has been a decrease in number of applicants applying to podiatric medical school. It suggested that this may be due unfamiliarity with profession medicine. The goal study is shed light on misconceptions and lack awareness medicine so can better bridge gap knowledge resultant strategy increase recruiting efforts. hypothesized high school college students will overestimate their podiatry significant percentage have low actual profession....
To assess efficacy and safety of dapsone in adult immune thrombocytopenia (ITP), a multicenter randomized controlled trial (RCT) real-word study cohort were performed. Participants adults with primary ITP, transient response to corticosteroids ± intravenous immunoglobulin, platelet count ≤ 30x109/L (or 50x109/L bleeding). Patients the RCT arm A (prednisone x3weeks+dapsone for 12 months) or B alone). The observational involved initiation at 100 mg/d standard follow-up. endpoint was rate...