A5101792208- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Meningioma and schwannoma management
- Vascular Malformations Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Epilepsy research and treatment
- Cerebrovascular and Carotid Artery Diseases
- Cerebral Venous Sinus Thrombosis
- Pharmacological Effects and Toxicity Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurofibromatosis and Schwannoma Cases
- Facial Nerve Paralysis Treatment and Research
- Moyamoya disease diagnosis and treatment
- Spine and Intervertebral Disc Pathology
- Reproductive Physiology in Livestock
- Musculoskeletal pain and rehabilitation
- Asthma and respiratory diseases
- Birth, Development, and Health
- Brain Metastases and Treatment
- Soft tissue tumors and treatment
- Lung Cancer Research Studies
- Reproductive Biology and Fertility
- Facial Rejuvenation and Surgery Techniques
- Dermatologic Treatments and Research
- Trigeminal Neuralgia and Treatments
International Peace Maternity & Child Health Hospital
2023-2025
Shanghai Jiao Tong University
2023-2025
Chang Gung Memorial Hospital
2018-2024
Chang Gung University
2013-2024
Chiayi Chang Gung Memorial Hospital
2015-2024
National Chung Cheng University
2018-2024
Harborview Medical Center
2018-2020
Nanjing Agricultural University
2018-2020
University of California, San Francisco
2020
Memorial Hospital
2020
To determine whether jugular venous reflux (JVR) is associated with cerebral white matter changes (WMCs) in individuals Alzheimer's disease (AD), we studied 12 AD patients 24 mild cognitive impairment (MCI) patients, and 17 elderly age- gender-matched controls. Duplex ultrasonography 1.5T MRI scanning was applied to quantify WMCs [T2 (WM) lesion dirty-appearing-white-matter (DAWM)]. Subjects severe JVR had more frequently hypertension (p = 0.044), WMC, including increased total 0.047)...
Objectives:Although diffusion tensor imaging (DTI) is widely studied to assess the motor outcome after ischaemic stroke, there paucity of data regarding outcomes intracerebral haemorrhage (ICH). The aim this study was determine DTI from different locations along corticospinal tract (CST) and association outcome.Methods:We prospectively recruited patients with deep ICH admitted our hospital November 2010 July 2012.Diffusion performed within 14 days onset ICH. Fractional anisotropy (FA)...
Abstract Post-traumatic endocrine dysfunction is a complication of traumatic brain injury (TBI). However, there lack long-term follow-up and large sample size studies. This study included patients suffering from TBI registered in the Health Insurance Database. Endocrine disorders were identified using ICD codes: 244 (acquired hypothyroidism), 253 (pituitary dysfunction), 255 (disorders adrenal glands), 258 (polyglandular 259 (other disorders) with at least three outpatient visits within 1...
The etiology of transient monocular blindness (TMB) in patients without carotid stenosis has been linked to ocular venous hypertension, for their increased retrobulbar vascular resistance, sustained retinal venule dilatation and higher frequency jugular reflux (JVR). This study aimed elucidate whether there are anatomical abnormalities at internal vein (IJV) TMB that would contribute impaired cerebral drainage consequent hypertension.Contrast-enhanced axial T1-weighted magnetic resonance...
Intracranial aneurysms after radiotherapy (RT) have previously been reported. However, the majority of studies were case reports. Therefore, we performed a nationwide study to explore risk radiation-induced intracranial aneurysms.This included patients diagnosed with head and neck cancer (ICD9: 140-149, 161). formation was identified using following ICD9 codes: nonruptured cerebral aneurysm (ICD9:4373), clipping (ICD9:3951). Patients who did not receive curative treatment those before...
Background: Lung cancers are common worldwide. First-line targeted therapy and chemotherapy both standard treatments in the current guidelines. With development of new anticancer therapy, lifespan patients with late-stage lung cancer has increased. Cardiovascular events can occur during treatment. This observational study aimed to report incidence major adverse cardiovascular (MACE) after treatment using real-world data. Objectives: Patients diagnosed advanced-stage between January 2011...
Abstract High-grade gliomas (HGGs) are a rapidly progressive and highly recurrent group of primary brain tumors. Despite aggressive surgical resection with chemoradiotherapy, prognoses remained poor. Valproic acid (VPA), histone deacetylase inhibitor has shown the potential to inhibit glioma cell growth in vitro through several diverse mechanisms. However clinical studies regarding effect VPA on HGGs limited. This study aimed investigate whether using patients under temozolomide (TMZ) would...
Abstract Objective We aim to compare the effect of long-term anti-seizure medication (ASM) monotherapy on risk death and new ischemic stroke in patients with post-stroke epilepsy (PSE). Patients methods identified all hospitalized (≥ 20 years) a primary diagnosis or hemorrhagic from 2001 2012 using National Health Insurance Research Database Taiwan. The PSE cohort were defined as (1) who had no ASMs use before index stroke, (2) after 14 days onset. receiving ASM enrolled categorized into...
Objective: This study aimed to investigate the association of maternal first-trimester vitamin D levels and supplementation during pregnancy with infant atopic dermatitis (AD) determine effect variables such as mode conception on association. Methods: was based Shanghai sub-cohort International Birth Cohort China. A total 4051 woman–infant pairs singleton pregnancies were recruited. Vitamin deficiency insufficiency defined serum 25-hydroxyvitamin concentrations 25 50 nmol/L, respectively. AD...
Perfusion-diffusion mismatch in magnetic resonance imaging (MRI) represents the non-core hypoperfused area acute ischemic stroke. The has been used to predict clinical response after thrombolysis stroke, but its role for predicting early neurological deterioration (END) stroke without not clarified yet. In this study, we prospectively recruited 54 patients with non-lacunar anterior circulation thrombolysis. All received first perfusion MRI within 24 hours from onset. Target profile was...
The aim of the present study was to investigate extensive invasion tumor cells into normal brain tissue, a life‑threatening feature malignant gliomas. How invasive migrate tissue and form secondary structure remains be elucidated. In study, morphological phenotypic changes glioma during in C6 model were investigated. stereotactically injected right putamen region adult Sprague‑Dawley rats. sections then subjected hematoxylin eosin, immunohistochemical or immunofluorescent staining. High...
Urinary creatinine excretion rate (CER) is an established marker of muscle mass. Low CER has been linked to poor coronary artery disease outcomes, but a link between and acute stroke prognosis not previously explored. We prospectively collected data from patients with (ischemic or hemorrhagic) within 24 hours symptom onset in Neurological Neurosurgery Intensive Care Unit Taiwan. Baseline (mg/d) was calculated by urine concentration morning spot multiplies 24-hour volume on the second day...
A 62-yr-old woman presented with incidentally detected left trigonal mass by magnetic resonance imaging (MRI) performed during workup for left-sided hearing loss and vertigo of 5-yr duration. Due to persistent dizziness, headache, progressive enlargement the tumor in follow-up scans, operation was planned. Because extended superiorly, a superior parietal lobule approach selected.She underwent craniotomy. strip electrode used localize motor sensory regions, neuronavigation confirm entry site....
Leptomeningeal carcinomatosis is found in around 4% of patients with non-small cell lung cancer. The most common radiological finding leptomeningeal diffuse enhancement on contrast-enhanced brain magnetic resonance imaging (MRI). Herein, we report a novel MRI — non-enhanced, band-like, symmetric restricted diffusion along the anterior surface brainstem four We also identified three additional cases similar findings literature review. hypothesized that was caused by malignant cells...
Abstract A 73-yr-old man presented with intractable left hemifacial spasm of 4 yr duration. Brain magnetic resonance imaging showed significant compression facial nerve by the vertebral artery (VA) and anterior inferior cerebellar (AICA). The patient underwent a retrosigmoid craniotomy microvascular decompression cranial (CN) VII. Intraoperatively, we found that distal AICA had protracted subarcuate extradural course. 1 This was relieved intra/extradural dissection. VA loop were compressing...