A5079882068- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Pediatric Hepatobiliary Diseases and Treatments
- Liver Diseases and Immunity
- Organ Transplantation Techniques and Outcomes
- Hepatitis C virus research
- Diet and metabolism studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Clinical Nutrition and Gastroenterology
- Gallbladder and Bile Duct Disorders
- Multiple Sclerosis Research Studies
- Advanced Neural Network Applications
- Peripheral Neuropathies and Disorders
- Intensive Care Unit Cognitive Disorders
- Gastrointestinal motility and disorders
- Endoplasmic Reticulum Stress and Disease
- IgG4-Related and Inflammatory Diseases
- COVID-19 and Mental Health
- Vitamin C and Antioxidants Research
- Diabetes Treatment and Management
- Pressure Ulcer Prevention and Management
- Model Reduction and Neural Networks
- Traumatic Ocular and Foreign Body Injuries
- Inflammatory Biomarkers in Disease Prognosis
- Alcohol Consumption and Health Effects
University of Pavol Jozef Šafárik
2018-2024
Univerzitná Nemocnica Louisa Pasteura
2020-2023
Chest radiography is a relatively cheap, widely available medical procedure that conveys key information for making diagnostic decisions. X-rays are almost always used in the diagnosis of respiratory diseases such as pneumonia or recent COVID-19. In this paper, we propose self-supervised deep neural network pretrained on an unlabeled chest X-ray dataset. The learned representations transferred to downstream task - classification diseases. results obtained four public datasets show our...
(1) Background: We present the first real-world-data study on teduglutide-treated SBS patients in Slovak Republic and to enable comparison of effects teduglutide treatment between adult pediatric populations. (2) Methods: This was a non-interventional retrospective cohort treated with teduglutide. Primary secondary endpoints were results use at 12 weeks 6 months after initiation treatment, compared baseline. (3) Results: Teduglutide led statistically significant reduction volume intravenous...
Hepatocellular carcinoma (HCC) has multiple molecular classes that are associated with distinct etiologies and, besides particular characteristics, also differ in clinical aspects. We aim to characterize the aspects of alcoholic liver disease-related HCC by a retrospective observational study included all consequent patients diagnosed MRI or histologically verified participating centers from 2010 2016. A total 429 were analysis, which 412 (96%) had cirrhosis at time diagnosis. The most...
Bacterial infections affect survival of patients with cirrhosis. Hospital-acquired bacterial present a growing healthcare problem because the increasing prevalence multidrug-resistant organisms. This study aimed to investigate impact an infection prevention and control programme coronavirus disease 2019 (COVID-19) measures on incidence hospital-acquired set secondary outcomes, including organisms, empiric antibiotic treatment failure, development septic states in cirrhosis.The was complex...
Cardiovascular diseases are currently one of the most important causes morbidity and mortality in liver transplant patients over long term. Therefore, evaluating prognostic factors for cardiovascular events (CVEs) this population is essential taking preventive measures. The aim study was to identify impact diabetes other metabolic disorders on CVEs patients. Three hundred fifty-six recipients who survived at least 6 months after surgery were enrolled. Patients followed a median time 118...
Ursodeoxycholic acid response score (URS) is a prognostic model that estimates the baseline probability of treatment after 12 months ursodeoxycholic (UDCA) therapy in patients with primary biliary cholangitis (PBC).To independently evaluate predictive performance URS model.We used cohort Slovak and Croatian treatment-naïve PBC to quantify discrimination ability using area under receiver operating characteristic curve (AUROC) its 95% confidence interval (CI). Furthermore, we evaluated...
Traumatic brain injury (TBI) is one of the most common trauma-related diagnoses among elderly population treated in emergency departments (ED). Identification patients with increased or decreased risk intracranial bleeding clinical importance. The objective this study was to evaluate implication cutaneous impact location (CIL) on prevalence after suspected confirmed TBI irrespective its severity.This a retrospective, single-center, descriptive observational geriatric aged 65 years and older...
Objective: To identify pretreatment laboratory parameters associated with treatment response and to describe the relationship between liver decompensation in patients primary biliary cholangitis treated ursodeoxycholic acid. Methods: We defined as both ALP ≤ 1.67 × ULN total bilirubin 2 ULN. Multiple logistic regression analyses were performed adjust for confounding effects of sociodemographic variables. Results: Pretreatment ((TB); OR = 0.3388, 95%CI 0.1671–0.6077), ALT (OR 0.5306,...
To compare NAFLD-related HCC and other etiology-related to describe predictive factors for survival in patients with independent of the BCLC staging system. We performed a multicenter longitudinal retrospective observational study diagnosed during period from 2010 through 2016. 12.59% had HCC, 21.91% either NAFLD or cryptogenic etiology. were younger (p = 0.0007), higher proportion women < 0.001) compared patients. The group significantly lower liver cirrhosis at time diagnosis 0.0001), they...
Background and Aims: Hepatocellular cancer (HCC) often occurs in geriatric patients. The aim of our study was to compare overall survival progression-free between patients (>75 years) younger than 75 years identify predictive factors with HCC. Material Methods: We performed a retrospective analysis HCC diagnosed Slovakia 2010−2016. Cases (HCC ≥75 were matched controls <74 based on the propensity score (gender, BCLC stage first-line treatment). Results: included 148 (84 men, 57%) There no...
: Neuromyelitis optica spectrum disorders (NMOSDs) are a group of rare, inflammatory, demyelinating diseases that affect the central nervous system. Neither incidence nor prevalence NMOSD has been determined in Slovakia thus far. The aim this study was to determine both and using 2015 International Panel diagnosis (IPND) criteria.: We performed population-based estimate during period from 1 January 2006 through 31 December 2019. cases were reported multiple sources subsequently verified IPND...