A5023300292- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Aortic Disease and Treatment Approaches
- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Aortic aneurysm repair treatments
- Cardiac and Coronary Surgery Techniques
- Pulmonary Hypertension Research and Treatments
- Infectious Aortic and Vascular Conditions
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac Imaging and Diagnostics
- Vascular Procedures and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Congenital Diaphragmatic Hernia Studies
- Tracheal and airway disorders
- Coronary Artery Anomalies
- Pericarditis and Cardiac Tamponade
- Cardiac tumors and thrombi
- Cardiovascular Issues in Pregnancy
- Veterinary Oncology Research
- Cardiovascular Effects of Exercise
- Cardiovascular and Diving-Related Complications
- Cardiac pacing and defibrillation studies
Metropolitan University
2024-2025
Osaka Metropolitan University
2022-2025
Tokyo Metropolitan University
2022-2025
The University of Tokyo
2013-2025
Okayama University
2024-2025
Veterinary Medical Center
2020-2025
Kagawa University Hospital
2022-2025
Shigei Medical Research Institute
2025
Nagasaki University Hospital
2021-2024
National Hospital Organization Takasaki Medical Center
2024
We demonstrate that the cooperative charge transfer among constructive molecules in organic crystals of tetrathiafulvalene-chloranil, i.e., bidirectional transition between neutral and ionic phases, can certainly be induced by irradiation a laser pulse with an 80-fs width. also report dynamics photoinduced neutral−ionic phase means time-resolved spectroscopic technique. Studies using various excitation intensities have shown photoconverted fraction (Φ) depends nonlinearly on intensity. In...
We investigated the prevalence and prognostic significance of functional mitral regurgitation (MR) tricuspid (TR) in patients with atrial fibrillation (AF) preserved left ventricular ejection fraction (LVEF).
Atrial functional mitral regurgitation (MR) has been recently described in patients with chronic atrial fibrillation (AF). However, the results of surgical valve (MV) repair for this type MR have not comprehensively reported. Our study aimed to address deficiency.We retrospectively studied 10 AF who underwent MV normal left ventricular dimension and preserved systolic function. All had heart failure (HF) symptoms at least one prior admission HF complicated by severe MR.Ring annuloplasty was...
ABSTRACT. We report a 10‐month‐old boy with acute meningo‐encephalitis associated exanthem subitum. It has recently been reported that human herpesvirus‐6 is the causative agent of subitum, and to our knowledge case first HHV‐6 infection.
Uncoupling protein 2 (UCP2) is an important regulator of intracellular reactive oxygen species (ROS) production. We determined the effects calorie restriction (CR) on dynamic aspects mitochondrial ROS production, UCP2, and nitric oxide (NO)-cGMP pathway in cardiovascular tissues type II diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Some rats were restricted diets (30% reduction from free intake) age 29 to 42 weeks. Blood glucose, hemoglobin A1c, plasma levels fatty acid,...
Cephalic arch stenosis (CAS) is a common cause of vascular access dysfunction in patients undergoing hemodialysis. This report describes case recurrent stent fractures and restenosis following endovascular treatment for CAS. A 34-year-old man with diabetic nephropathy chronic hemodialysis underwent multiple placements Complications, including entanglement during balloon angioplasty fracture due to the cephalic arch's anatomical characteristics, necessitated surgical intervention. highlights...
Kommerell diverticulum (KD) with an aberrant subclavian artery is a rare congenital anomaly that often resembles saccular aneurysm. Open surgery the traditional treatment; however, recent reports have suggested success endovascular or hybrid approaches. This study aimed to show results of stent graft-based treatment and demonstrate aneurysmal reduction rate in KD. Five patients KD underwent therapy at Osaka Metropolitan University Hospital between May 2009 February 2024. Patient data...
Human epidermal growth factor receptor 2 (HER2) is a known therapeutic target in canine osteosarcoma (OSA); however, the efficacy of anti-HER2 antibody drugs remains unclear. This study aimed to investigate effects including trastuzumab and emtansine (T-DM1) on OSA cell lines vitro vivo. Four (HMPOS, POS, OOS, HOS) were used. Western blotting revealed HER2 protein expression all lines. Although water-soluble tetrazolium salt assays showed inhibitory activity T-DM1 against vitro, was...
Hospital-associated disability (HAD), characterized by a worsening of activities daily living and physical function following hospitalization, is common complication in older adults during the course acute care hospitalization. HAD significant concern affecting undergoing transcatheter aortic valve implantation (TAVI). This retrospective study investigated 243 consecutive patients who underwent elective transfemoral TAVI between January 2016 April 2022. was defined as decrease at least 1...
Artificial chordal reconstruction technique uses several expanded polytetrafluoroethylene loops to achieve mitral valve repair. We studied retrospectively 180 patients who underwent repair using the loop via median sternotomy: 86 for posterior leaflet prolapse, 48 anterior prolapse and 26 bileaflet prolapse. Of patients, 138 required 1 set; 40 2 with Barlow's disease 3. Loop sets contained two nine ranging in length from 14 mm. Additional techniques ensure complete included commissural...
Podoplanin (PDPN), a small transmembrane mucin-like glycoprotein, is ectopically expressed on tumor cells. PDPN known to be linked with several aspects of malignancies in certain types human and canine tumors. Therefore, it considered novel therapeutic target. Monoclonal antibodies targeting cells showed obvious anti-tumor effects preclinical studies using mouse models. Previously, we generated cancer-specific mouse–dog chimeric anti-PDPN antibody, P38Bf, which specifically recognizes In...
Abstract Background Aortic valve perforation is a rare complication of blunt chest trauma. We report case delayed aortic insufficiency presenting several months after Case presentation A 17-year-old male presented to the emergency department with traumatic brain injuries and trauma, but no evidence cardiac injuries. Three later, he developed acute heart failure due severe regurgitation left ventricular dysfunction. sizable tear in right coronary cusp caused insufficiency. He was treated...
Esophageal echocardiography was developed for recording left ventricular anterolateral wall (LVAW) echocardiograms and applied clinically to 14 normal subjects 21 patients with coronary artery disease. LVAW were obtained satisfactorily in 11 of (75%) 20 (95%) by conventional anterior eight (38%) In subjects, mm/sec (mean 34.3 +/- 5.2 mm/sec); diastolic thickness ranged from 9-12.5 mm 11.2 0.7 mm). disease, motion esophageal classified into five groups according the excursion, findings good...
Aneurysmal circumflex coronary artery (Cx) with fistulous connection to the sinus is a rare clinical entity that usually remains asymptomatic until later in life, so ideal therapeutic strategy poorly defined. The timing of surgical treatment for patients big issue, and whether leave or exclude diffuse aneurysm addition ligation fistula controversial, considering native myocardial circulation. Complete repair, including exclusion diffusely aneurysmal Cx revascularization graftable branch area...
Podoplanin (PDPN), a small transmembrane mucin-like glycoprotein, is ectopically expressed. It also known to be linked with several aspects of tumor malignancy in some types human tumors, including invasion, metastasis, and cancer stemness. However, there are few reports on the expression dog PDPN (dPDPN) canine association between dPDPN has not been elucidated. We identified that 11 out 18 tumors expressed dPDPN. Furthermore, 80% malignant melanoma (MM), squamous cell carcinoma, meningioma...
Histologically, the mitral valve annulus comprises a collection of collagen fibres. However, existence fibres in tricuspid has not been elucidated. Our goal was to clarify histology annulus.Fifty human hearts without heart disease that were autopsied at Osaka City University Hospital between January 2009 and December 2017 examined. The sectioned 12 sites around annulus, atrioventricular junction distance measured.None samples had continuous aggregation could be called an annulus....