Hirokazu Arai

ORCID: 0000-0002-1415-4831
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About
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Research Areas
  • Motivation and Self-Concept in Sports
  • Neonatal Respiratory Health Research
  • Youth Development and Social Support
  • Congenital Diaphragmatic Hernia Studies
  • Physical Education and Pedagogy
  • Behavioral Health and Interventions
  • Neuroscience of respiration and sleep
  • Physical Activity and Health
  • Diverse Approaches in Healthcare and Education Studies
  • Cancer survivorship and care
  • Sport Psychology and Performance
  • Childhood Cancer Survivors' Quality of Life
  • Psychosocial Factors Impacting Youth
  • Neonatal and fetal brain pathology
  • Respiratory Support and Mechanisms
  • Sport and Mega-Event Impacts
  • Children's Physical and Motor Development
  • Infant Development and Preterm Care
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Neonatal Health and Biochemistry
  • Inclusion and Disability in Education and Sport
  • Education and Learning Interventions
  • Prenatal Screening and Diagnostics
  • Lymphatic System and Diseases
  • Proteoglycans and glycosaminoglycans research

Hosei University
2015-2025

Akita Red Cross Hospital
2016-2025

Saitama Medical University
2022

Japan University of Economics
2021

Chuo University
2021

JTEKT (Japan)
2019-2021

National Center for Global Health and Medicine
2020

Asahi Kasei (Japan)
2017-2020

Tokyo Institute of Technology
2020

Ryutsu Keizai University
2018

On 24 March 2020, an announcement was made that the Tokyo 2020 Olympic and Paralympic games would be postponed until 2021 due to coronavirus pandemic. Athletes their coaches have experienced a wide spectrum of emotional cognitive reactions such as disappointment, frustration, confusion, relief, name few. The current article aimed summarize athletes' coaches' related repercussions triggered by postponement Games in Japan, discuss how values sports athletes or are likely changed.

10.1080/15325024.2020.1777762 article EN Journal of Loss and Trauma 2020-06-12

Introduction: A recent scoping review identified histological chorioamnionitis (HCA), small for gestational age (SGA), and bubbly/cystic appearance on chest X-ray (bubbly/cystic CXR) as risk factors severe bronchopulmonary dysplasia (BPD). To further validate these results, a large-scale database was analyzed. Methods: This retrospective multicenter cohort study included infants born at <28 weeks' between 2003 2016. The validated from the were analyzed independent associations with BPD...

10.1159/000543810 article EN cc-by-nc Neonatology 2025-01-27

Infants born in Japan are reported to have a low incidence of necrotizing enterocolitis (NEC) among countries, and these differences remained significant after adjusting for common clinical factors. To investigate the impact ethnic background, we compared NEC between infants those mothers Japanese ethnicity California. Preterm 2008 2019 at 22–29 weeks gestational age were analyzed retrospectively. Four groups analyzed: (JP), California (JP-J), with but United States or another country...

10.1038/s41598-025-92393-y article EN cc-by-nc-nd Scientific Reports 2025-03-22

Objectives High physical activity levels have been associated with longer, healthier lifespans and improved quality of life among breast cancer survivors. The Japanese clinical guidelines for survivors, similar to those in the USA, strongly recommend maintaining high levels. However, extent adherence these survivors Japan is unclear. This study aimed assess guideline-recommended activities identify factors. Methods Self-administered questionnaires were distributed without recurrence or...

10.1136/spcare-2024-005253 article EN BMJ Supportive & Palliative Care 2025-04-02

A psychometric scale for assessing cancer-related worry among cancer patients, called the Brief Cancer-Related Worry Inventory (BCWI), was developed.A cross-sectional questionnaire survey item development conducted of 112 Japanese patients diagnosed with breast cancer, and test-retest validation analysis using data from another prospective study 20 lung patients. The contained 15 newly developed items worry, Hospital Anxiety Depression Scale, Impact Event Scale Revised, Medical Outcomes...

10.1002/pon.1348 article EN Psycho-Oncology 2008-05-06

Quantitation of glycosaminoglycans (GAGs) in the lungs from different age groups indicated that amount GAGs was lower group 70 yr and older compared with 30 to 39 40 49 age, respectively (p less than 0.05). There no difference relative ratio individual GAG species (hyaluronic acid: chondroitin sulfate (A(C): dermatan sulfate: heparan sulfate) lung among 49, 50 59, 60 69, or more age. Hence, it suggested senescence associated a uniform decrease all lung. On contrary, emphysematous were...

10.1164/arrd.1982.126.5.797 article EN PubMed 1982-11-01

Therapeutic hypothermia is recommended for moderate and severe neonatal encephalopathy, but being applied to a wider range of neonates than originally envisaged. To examine the clinical use therapeutic hypothermia, data collected during first 3 years (2012-2014) Baby Cooling Registry Japan were analysed. Of 485 cooled neonates, 96.5% ≥36 weeks gestation 99.4% weighed ≥1,800 g. Severe acidosis (pH < 7 or base deficit ≥16 mmol/L) was present in 68.9%, 96.7% required resuscitation >10 min....

10.1038/srep39508 article EN cc-by Scientific Reports 2017-01-04

Lack of sufficient physical activity in youth is a worldwide concern. School-based extracurricular sports activities (SBECSA) are considered central opportunity to increase activity. However, the factors that influence students' participation SBECSA not well established. Therefore, purpose present study was clarify perceived motivation Japanese students participate SBECSA. Semi-structured interviews were conducted with 23 junior high and school who participated The KJ method used...

10.1080/02673843.2019.1700139 article EN cc-by International Journal of Adolescence and Youth 2019-12-06

Background. Many studies have suggested a possible aetiological role for obstetric complications in the development of schizophrenia. We focused on prenatal physical growth schizophrenia, contentious issue literature. Methods. compared gestational age at birth, birth weight (BW) and head circumference (BHC) between 312 schizophrenics 517 controls, 187 their matched healthy siblings. Information histories was obtained from Maternal Child Health Handbooks (i.e. contemporaneous records)....

10.1017/s003329179900210x article EN Psychological Medicine 2000-05-01

Abstract Background Bubbly/cystic appearance on chest radiograph is an important factor in severe‐type bronchopulmonary dysplasia ( BPD ) Japan. The aim of this study was to determine the perinatal characteristics and neonatal complications bubbly/cystic(+) group extremely preterm infants with , that is, oxygen dependency at day 28 after birth 28). Methods This a multicenter retrospective cohort population data from (birthweight, &lt;1,500 g) enrolled Neonatal Research Network Of 15 480 born...

10.1111/ped.13786 article EN Pediatrics International 2019-01-13

In this study, the reactive extrusion mechanism of fiber-reinforced polyamide 66 materials with added carbodiimide was clarified, and mechanical tribological properties were evaluated. Increasing molecular weight resin is one methods that has been proposed to improve wear resistance toughness materials. This study proposes a method using poly-carbodiimide compounds. The effects feeding position compounds in twin screw extruder, type compounds, proportion on reaction static elucidated. glass...

10.1016/j.matdes.2019.108447 article EN cc-by Materials & Design 2019-12-23

Abstract Objectives This study aimed to develop a structural model for mammography adoption in Japanese middle‐aged women by using constructs from the transtheoretical (TTM), theory of planned behavior (TPB), implementation intentions, and cancer worry. Methods Questionnaires based on items including TTM, TPB, worry‐related variables, demographic variables were distributed 1000 adult aged 40 59 years, with 641 subjects being used final analysis (response rate = 64.1%). Results Regarding...

10.1002/pon.3293 article EN Psycho-Oncology 2013-05-10

Purinergic receptor expression and involvement in steroidogenesis were examined NCI-H295R (H295R), a human adrenal cortex cell line which expresses all the key enzymes necessary for steroidogenesis. mRNA/protein multiple P1 (A2A A2B), P2X (P2X5 P2X7), P2Y (P2Y1, P2Y2, P2Y6, P2Y12, P2Y13, P2Y14) purinergic receptors detected H295R. 2MeS-ATP (10–1000 µM), P2Y1 agonist, induced glucocorticoid (GC) secretion dose-dependent manner, while other extracellular purine/pyrimidine agonists (1–1000 µM)...

10.1371/journal.pone.0071022 article EN cc-by PLoS ONE 2013-08-08

Abstract The optimal method of the polymer Materials Informatics (MI) has not been developed because amorphous nature higher-order structure affects these properties. We have now tried to develop MI’s descriptor using persistent homology as topological method. experimentally studied influence MD simulation cell size on its electrical properties important for a soft material sensor or actuator device. all-atom calculated and obtained atomic coordinate analyzed by homology. change in different...

10.1038/s41598-021-80975-5 article EN cc-by Scientific Reports 2021-01-26

Beckwith-Wiedemann syndrome (BWS) is the most common congenital overgrowth involving tumor predisposition. BWS caused by various epigenetic or genetic alterations that disrupt imprinted genes on chromosome 11p15.5 and clinical findings of are highly variable. Hyperinsulinemic hypoglycemia reported in about half all babies with BWS. We identified an infant diazoxide-unresponsive hyperinsulinism (HI) without any apparent features suggestive BWS, but diagnosed molecular testing. The patient...

10.1507/endocrj.ej12-0242 article EN Endocrine Journal 2012-11-30

This study aimed to evaluate the capability of a piezoelectric sensor detect heart murmur in patients with congenital defects. Heart sounds and murmurs were recorded using an electronic stethoscope healthy neonates (n = 9) systolic caused by defects who born at hospital. Signal data digitally filtered high-pass filtering, envelope processed signals was calculated. The amplitudes evaluated signal-to-noise ratio compared between those In addition, correlation determined. detected significantly...

10.3390/s21041376 article EN cc-by Sensors 2021-02-16

The presence of a large quantity hyaluronic acid in the tissue pleural mesothelioma was confirmed by means histochemical methods and application hyaluronidase from Streptomyces hyalurolyticus, which is strictly specific for acid.

10.1164/arrd.1975.111.5.699 article EN PubMed 1975-05-01

The ESC2 gene encodes a protein with two tandem C-terminal SUMO-like domains and is conserved from yeasts to humans. Previous studies have implicated Esc2 in silencing. Here, we explore the functional significance of describe novel role for promoting genome integrity during DNA replication. This study shows that esc2Delta cells are modestly sensitive hydroxyurea (HU) defective sister chromatid cohesion reduced life span, these effects enhanced by deletion RRM3 Pif1-like helicase. rrm3Delta...

10.1534/genetics.107.086249 article EN Genetics 2008-09-01
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