- Parathyroid Disorders and Treatments
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Bone health and treatments
- Advanced MRI Techniques and Applications
- Cardiac Ischemia and Reperfusion
- Thyroid Disorders and Treatments
- Neonatal Respiratory Health Research
- Bone health and osteoporosis research
- Heart Rate Variability and Autonomic Control
- Genetic Syndromes and Imprinting
- Magnesium in Health and Disease
- Cardiovascular Function and Risk Factors
- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Thyroid Cancer Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Vitamin D Research Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Neonatal and fetal brain pathology
- Cardiovascular Effects of Exercise
- Cerebrospinal fluid and hydrocephalus
- Growth Hormone and Insulin-like Growth Factors
- Coronary Interventions and Diagnostics
Nagaoka Red Cross Hospital
2014-2025
Niigata University Medical and Dental Hospital
2018-2024
Kyushu Okinawa Agricultural Research Center
2014-2024
Niigata University
2012-2024
National Agriculture and Food Research Organization
2023
Nagano Municipal Hospital
2004-2021
Banner - University Medical Center Phoenix
2018
University of Arizona
2018
Shinshu University
2004-2014
Akebono (Japan)
2012
To study the recovery in phonation after reconstruction of recurrent laryngeal nerve (RLN) patients whose thyroid cancer was invading nerve, and to evaluate role ansa cervicalis RLN anastomosis (ARA) operations for cancer.Retrospective study.University hospital private clinic hospital, Japan.34 with who underwent unilateral 331 consecutive operated on cancer.Reconstruction direct (DA), free grafting (FNG), vagus-RLN (VRA) or ARA, including behind cartilage.Maximum time (34 normal subjects 26...
OBJECTIVE: A significant decrease in vitamin D receptor (VDR) and calcium-sensing (CaSR) protein expression has been demonstrated recently parathyroid (PT) adenomas. In this study, we investigated the relationships between proliferative activity of glands (PTGs) VDR as well CaSR, compared it with clinical severity patients primary hyperparathyroidism (1 degrees HPT). DESIGN: Seven 1 HPT were included study. Four thyroid carcinoma served controls. METHODS: Immunohistochemical staining was...
Objective: High-flow nasal cannula (HFNC) is generally considered to have fewer enteral feeding problems than continuous positive airway pressure (NCPAP) or intermittent positive-pressure ventilation (NIPPV). However, the effects of HFNC on outcomes in preterm infants are still controversial. The aim this study was assess effect postnatal growth and feeding. Study design: We conducted a secondary analysis multicenter randomized controlled trial. Preterm born at <34 weeks were randomly...
OBJECTIVES: Our aim is to compare the efficacy and safety of high-flow nasal cannula (HFNC) against those continuous positive airway pressure (NCPAP) or intermittent positive-pressure ventilation (NIPPV) after extubation in preterm infants. METHODS: This prospective, randomized, noninferiority trial was conducted 6 tertiary NICUs. Infants born at &lt;34 weeks who needed noninvasive were enrolled. We randomly assigned infants an HFNC group when used NCPAP/NIPPV NCPAP NIPPV used. The...
Abstract A major challenge in the management of primary hyperparathyroidism (pHPT) is decision regarding which patients should undergo parathyroidectomy (PTX), although Consensus Development Conference NIH has proposed guidelines for indication surgery. In present study, changes bone mineral density (BMD) after PTX were compared between pHPT who did and not meet criteria, we further tried to predict BMD change from preoperative parameters. The subjects 44 (30 women 14 men) had successful...
Although many reports have demonstrated the sustained increase in bone mineral density (BMD) at trabecular sites primary hyperparathyroidism (pHPT) after parathyroidectomy (PTX), there been no data available on BMD changes over long-term pHPT patients with and without PTX Japanese population. The present study was designed to investigate both cortical or PTX.The subjects were 97 who had followed up Kobe University Hospital for least 1 year 6 years PTX. recommended all whose pathological...
Therapeutic hypothermia is recommended for moderate and severe neonatal encephalopathy, but being applied to a wider range of neonates than originally envisaged. To examine the clinical use therapeutic hypothermia, data collected during first 3 years (2012-2014) Baby Cooling Registry Japan were analysed. Of 485 cooled neonates, 96.5% ≥36 weeks gestation 99.4% weighed ≥1,800 g. Severe acidosis (pH < 7 or base deficit ≥16 mmol/L) was present in 68.9%, 96.7% required resuscitation >10 min....
We report a new type of thyrotoxicosis (postaspiration thyrotoxicosis) that occurred after needle aspiration thyroid cysts. In retrospective study five patients with cysts developed transient without significant symptoms hyperthyroidism aspiration. These had elevated serum hormone levels suppressed TSH and radioiodine uptake. The content in the cystic fluid was greater who than did not. prospective we examined function tests 52 consecutive 63 solid nodules confirmed an occurrence...
Parathyroid cancer is rare but relatively frequent in Japan compared to Western countries. Surgical parathyroidectomy the primary choice for radical treatment of hyperparathyroidism (pHPT), hence it important distinguish malignant from benign tumor determination surgical indication as well method operation. However, not easy diagnose parathyroid prior In present study, we analyzed background data, biochemical data and bone mineral density (BMD) 131 patients with pHPT (111 20 malignant). BMD...
OBJECTIVE Genetic contributions to bone mineral density (BMD) and turnover are well known. In the present study, we analysed relationship between restriction fragment length polymorphisms of PTH gene development primary hyperparathyroidism (pHPT) as its severity. PATIENTS Seventy‐nine pHPT patients 104 age‐matched healthy controls were analysed. DESIGN AND MEASUREMENTS genotypes determined by polymerase chain reaction Bst B I or Dra II polymorphisms. The presence absence sites indicated b D...
To clarify the pathophysiology of normal pressure hydrocephalus (NPH) after subarachnoid hemorrhage, authors measured cerebral blood flow (CBF), oxygen metabolic rates (CMRO2), extraction fraction (OEF), and volume (CBV) in eight volunteers, six SAH patients with NPH, seven without NPH by 15O-labeled gas positron emission tomography (PET). In group, PET revealed a decrease CBF lower regions cortex diffuse CMRO2. The frontal, temporal, occipital cortices was significantly greater than non-NPH...
Therapeutic hypothermia following neonatal encephalopathy is neuroprotective. However, approximately one in two cooled infants still die or develop permanent neurological impairments. Further understanding of variables associated with the effectiveness cooling important to improve therapeutic regimen. To identify clinical factors short-term outcomes infants, data 509 registered Baby Cooling Registry Japan between 2012 and 2014 were evaluated. Independent death during initial hospitalization...
<b><i>Introduction:</i></b> Bronchopulmonary dysplasia (BPD) is associated with neurodevelopmental outcomes of preterm infants, but its effect on brain growth in infants after the neonatal period unknown. This study aimed to evaluate severe BPD from term 18 months corrected age (CA). <b><i>Methods:</i></b> Sixty-three (42 and 21 without BPD) who underwent magnetic resonance imaging at equivalent (TEA) CA were studied by using Infant Brain...
Generalized arterial calcification of infancy (GACI) is a rare disease characterized by calcification. GACI caused mutation in the ENPP1 or ABCC6 genes. causes severe hypertension and heart failure, approximately 50% patients die within first 6 months. In particular, preterm infants with often due to immature cardiac function. Bisphosphonates are effective treating GACI; however, no standardized treatment regimen available. We experienced case infant born at 30 weeks gestation....