A5040277439- Infant Nutrition and Health
- Birth, Development, and Health
- Neonatal Respiratory Health Research
- Breastfeeding Practices and Influences
- Congenital Diaphragmatic Hernia Studies
- Child Nutrition and Water Access
- Fatty Acid Research and Health
- Infant Development and Preterm Care
- Pregnancy and preeclampsia studies
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Gestational Diabetes Research and Management
- Child Nutrition and Feeding Issues
- Clinical Nutrition and Gastroenterology
- Metabolism and Genetic Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Diet and metabolism studies
- Neonatal and fetal brain pathology
- Congenital Heart Disease Studies
- Cell Adhesion Molecules Research
- Cancer, Stress, Anesthesia, and Immune Response
- Neonatal Health and Biochemistry
- Pancreatic function and diabetes
- Neuropeptides and Animal Physiology
- Growth Hormone and Insulin-like Growth Factors
Juntendo University
2016-2025
Juntendo University Hospital
2023-2024
Toshima Hospital
2024
Taiho Pharmaceutical (Japan)
2023
Juntendo University Shizuoka Hospital
2023
St Mary's Hospital
2017
Kaiser Permanente
2011
Ludwig-Maximilians-Universität München
2006-2009
Boston University
2005
Miyazaki Welfare Medical College
1994-1995
Abstract The international spread of COVID-19 infection has attracted global attention, but the impact local or domestic travel restriction on public transportation network remains unclear. Passenger volume data for in Japan and time at which first confirmed case was observed each prefecture were extracted from sources. A survival approach a hazard modeled as function closeness centrality utilized to estimate risk importation prefecture. total 46 prefectures with imported cases identified....
We sought to clarify the features of kernicterus in preterm infants.The subjects this study were 8 infants with athetoid cerebral palsy whose gestational ages < or =34 weeks. retrospectively investigated clinical, laboratory, MRI, and brainstem auditory evoked potential (BAEP) findings.Gestational age was =26 weeks 6 infants, birth weight <1000 g 5 infants. Serious postnatal complications systemic deterioration observed 3 Total bilirubin levels measured frequently majority infants; peak...
ABSTRACT Objectives: Transforming growth factor (TGF) β1 displays a broad spectrum of activities in mucosal regulation, including induction oral tolerance, potent anti‐inflammatory effects, IgA expression and effects on epithelial cell proliferation differentiation. The present study examined the effect probiotics immunologic system preterm infants relation to TGF‐β signaling. Methods: Subjects comprised 19 divided into 2 groups: receiving Bifidobacterium breve supplementation ( B. group)...
Short-chain fatty acids (SCFAs) are known to provide energy colonocytes, whereas overproduction of SCFAs can cause mucosal injury in premature infants. Our objective was investigate the effects oral administration Bifidobacterium breve M-16V (B breve) on fecal lactic acid and low birth weight (LBW) infants.Fecal lactic, acetic, propionic, butyric from 66 infants were analyzed by high-performance liquid chromatography at 0, 2, 4 weeks after birth. The subjects included 22 extremely LBW (ELBW,...
Biliary atresia (BA) is among the commonest indications for liver transplantation (LT) in children. We examined whether serum matrix metalloproteinase-7 (MMP-7) useful diagnosis of BA Japanese infants, and MMP-7 concentrations before after Kasai portoenterostomy (KP) predicted LT within a year.Subjects under 6 months old at eight pediatric centers Japan were enrolled retrospectively, including patients with cholestasis normal controls (NC) without disease. Patients divided into groups...
This study aimed to evaluate the effects of psychosocial and neurodevelopmental disorders on pediatric ulcerative colitis management. Specifically, relationships between these disease severity, as well treatment strategies, were assessed through a single-center, retrospective, observational study. The included patients with (UC) under 15 years age diagnosed by colonoscopy histological evaluation January 2022 May 2024. Data comorbid functional gastrointestinal obtained from patients'...
Infants born in Japan are reported to have a low incidence of necrotizing enterocolitis (NEC) among countries, and these differences remained significant after adjusting for common clinical factors. To investigate the impact ethnic background, we compared NEC between infants those mothers Japanese ethnicity California. Preterm 2008 2019 at 22–29 weeks gestational age were analyzed retrospectively. Four groups analyzed: (JP), California (JP-J), with but United States or another country...
Anthracycline chemotherapy improves survival rates in childhood cancer patients but poses a significant risk of late-onset cardiotoxicity, potentially leading to cardiac dysfunction and heart failure. Recently, flow dynamics parameters derived from two-dimensional fluid may be sensitive indicators dysfunction. Topological Flow Data Analysis (TFDA) mathematically defines vortical structures offers novel approach function assessment. This study aimed use TFDA analyze the left ventricular...
Human milk contains many kinds of antioxidant and is considered to prevent diseases mediated by oxygen free radicals in very low birthweight (VLBW) infants.To examine the effects breast VLBW infants determining urinary 8-hydroxydeoxyguanosine (8-OHdG) excretion, which known be a non-invasive marker for vivo oxidative DNA damage.Urinary 8-OHdG concentrations were measured 15 fed 14 formula at 2, 7, 14, 28 days age.Urinary excretion age was significantly lower than 2 7 group, group.This first...
Lower gastrointestinal bleeding (LGB), particularly in newborns, is of serious concern and requires urgent investigation hospital care. Whereas allergic proctocolitis caused by food protein a significant cause LGB infants with eosinophilia, there are several cases diseases symptoms similar to those but without an apparent reaction influence.We examined 2 neonates using rectosigmoidoscopy who showed eosinophilia experienced fresh soon after birth before their first feedings. Serum eosinic...
Background The controlling nutritional status (CONUT) score (CS), a simple for assessing status, is calculated using laboratory data, including serum albumin concentration. Although dye-binding assays such as the bromocresol green (BCG) and modified purple (mBCP) methods are widely used measurement, acute-phase proteins interfere with BCG method. Objective We aimed to determine whether choice of assay affects assessment CONUT scores (CSs). Design measured concentrations by (ALB ) mBCP in 44...
We investigated the relationship between plasma insulin-like growth factor I (IGF-I), leptin, active ghrelin levels, and postnatal in very low birth weight (VLBW) infants.Plasma IGF-I, levels were measured at 2, 4, 6 8 weeks after 61 VLBW infants, including 31 appropriate-for-gestational-age (AGA) 30 small-for-gestational-age (SGA) infants.Insulin-like lowest birth, but increased gradually over first of life. IGF-I was positively correlated with body weight, length mass index all time...
Neonatal sepsis is difficult to diagnose and pathogens cannot be detected from blood cultures in many cases. Development of a rapid accurate method for detecting thus essential. The main purpose this study was identify etiological agents clinically diagnosed neonatal using bacterial ribosomal RNA-targeted reverse transcription-quantitative PCR (BrRNA-RT-qPCR) conduct comparisons with the results conventional culture. Since BrRNA-RT-qPCR targets RNA, detection rates approach may exceed those...