Jialong Guo

ORCID: 0000-0003-2292-4979
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About
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Research Areas
  • Rheumatoid Arthritis Research and Therapies
  • Systemic Lupus Erythematosus Research
  • Monoclonal and Polyclonal Antibodies Research
  • Cytokine Signaling Pathways and Interactions
  • Urinary Bladder and Prostate Research
  • Cancer Mechanisms and Therapy
  • Chemokine receptors and signaling
  • Blood Coagulation and Thrombosis Mechanisms
  • Cardiovascular Health and Disease Prevention
  • Chronic Lymphocytic Leukemia Research
  • Traditional Chinese Medicine Studies
  • Liver Disease Diagnosis and Treatment
  • Multiple Myeloma Research and Treatments
  • Vascular anomalies and interventions
  • Spondyloarthritis Studies and Treatments
  • Cardiovascular Conditions and Treatments
  • Viral Infections and Immunology Research
  • Bladder and Urothelial Cancer Treatments
  • HER2/EGFR in Cancer Research
  • Ultrasound and Hyperthermia Applications
  • T-cell and B-cell Immunology
  • Autoimmune and Inflammatory Disorders Research
  • Traditional Chinese Medicine Analysis
  • Renal Diseases and Glomerulopathies
  • Psoriasis: Treatment and Pathogenesis

Southern University of Science and Technology
2024

Jilin University
2013-2021

Union Hospital
2015-2021

Union Hospital
2013-2021

Taichung Veterans General Hospital
2015

Peking University
2007

Peking University People's Hospital
2007

IHI Corporation (United States)
2006

In rheumatoid arthritis (RA), fibroblast-like synoviocytes (FLS) present a unique aggressive phenotype and have passive response to the inflammatory microenvironment, which are critical for disease's progression. KDM4B, as histone demethylase, functions an oncogenic factor in many cancers is implicated osteoclastogenesis well pro-inflammatory cytokine release diseases. However, effects of KDM4B on RA FLS not been reported. To investigate this issue, our study determined expression using...

10.1007/s10528-021-10042-1 article EN cc-by Biochemical Genetics 2021-04-28

To investigate the relationship between Brachial-ankle pulse wave velocity (baPWV), and its associated risk factors in Chinese patients with RA.138 RA 150 healthy subjects were included. baPWV of all participants was measured. related determined, as well traditional cardiovascular factors.baPWV significant higher group (1705.44 ± 429.20 cm/s) compared to control (1386.23 411.09 (P < 0.001). Compared low group, high significantly older = 0.008) taller 0.033). Serum cholesterol 0.035),...

10.1155/2013/342869 article EN cc-by Clinical and Developmental Immunology 2013-01-01

Abstract Aim The aim of this study was to determine the efficacy and safety a weekly dose leflunomide (50 mg/week) in early rheumatoid arthritis patients with mild or moderate disease activity. Methods (ERA) activity were randomly selected for inclusion assigned either treatment group (leflunomide 50 mg/week, LEF50) control 10 mg/day, LEF10). All treated 24 weeks. Clinical assessed using score 28 joints ( DAS 28) ‐ erythrocyte sedimentation rate (ESR) European League Against Rheumatism EULAR...

10.1111/1756-185x.12677 article EN International Journal of Rheumatic Diseases 2015-08-13

Following the publication of this paper, authors alerted Editorial Office to fact that a reader had informed them miR‑152 overexpression did not affect cell apoptosis and cycle. The subsequently confirmed they were unable obtain consistent results from these experiments.Furthermore, an independent investigation paper revealed apoptotic data shown in Fig. 2D strikingly similar those appeared article published previously with different authors, although one institutions was held common. have...

10.3892/ijmm.2021.5007 article EN cc-by International Journal of Molecular Medicine 2021-07-14
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