Dongdong Wu

ORCID: 0000-0003-2368-2035
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About
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Research Areas
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Supramolecular Self-Assembly in Materials
  • Synthesis and biological activity
  • Advanced biosensing and bioanalysis techniques
  • Crystal structures of chemical compounds
  • Synthesis of Organic Compounds
  • RNA Interference and Gene Delivery
  • GaN-based semiconductor devices and materials
  • Synthetic Organic Chemistry Methods
  • Conducting polymers and applications
  • Advanced Polymer Synthesis and Characterization
  • Polymer Surface Interaction Studies
  • Radical Photochemical Reactions
  • Ga2O3 and related materials
  • Quantum Dots Synthesis And Properties
  • Oxidative Organic Chemistry Reactions
  • Photochromic and Fluorescence Chemistry
  • Polydiacetylene-based materials and applications
  • Tissue Engineering and Regenerative Medicine
  • 2D Materials and Applications
  • Axial and Atropisomeric Chirality Synthesis
  • Biosensors and Analytical Detection
  • Electrospun Nanofibers in Biomedical Applications
  • Constructed Wetlands for Wastewater Treatment

Sichuan University
2023-2025

China Automotive Technology and Research Center
2024

Tiangong University
2024

Chinese PLA General Hospital
2023-2024

Harbin Institute of Technology
2024

Jiangnan University
2024

Suzhou Institute of Nano-tech and Nano-bionics
2015-2023

Chinese Academy of Sciences
2012-2023

Handan College
2023

Nanjing University
2009-2022

We report that phosphotyrosine–cholesterol conjugates effectively and selectively kill cancer cells, including platinum-resistant ovarian cells. The conjugate increases the degree of noncovalent oligomerization upon enzymatic dephosphorylation in aqueous buffer. This conversion also results assembly cholesterol inside outside cells leads to cell death. Preliminary mechanistic studies suggest formed assemblies not only interact with actin filaments microtubules but affect lipid rafts. As...

10.1021/jacs.6b06075 article EN publisher-specific-oa Journal of the American Chemical Society 2016-08-16

This paper investigates the performance of AlGaN/gallium nitride (GaN) MIS high electron mobility transistors (MIS-HEMTs). The gate dielectric layer and surface passivation are formed by low-pressure chemical vapor deposition (LPCVD) Si <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> N xmlns:xlink="http://www.w3.org/1999/xlink">4</sub> . LPCVD-Si MIS-HEMTs exhibit a breakdown voltage (BV) 1162 V at I...

10.1109/ted.2015.2510445 article EN IEEE Transactions on Electron Devices 2016-01-01

Protocells have garnered considerable attention from cell biologists, materials scientists, and synthetic biologists. Phase-separating coacervate microdroplets emerged as a promising cytomimetic model because they can internalize concentrate components dilute surrounding environments. However, the membrane-free nature of such coacervates leads to coalescence into bulk phase, phenomenon that is not representative cells are designed mimic. Herein, we develop membranized peptide (PC) with...

10.1021/jacs.3c07748 article EN Journal of the American Chemical Society 2023-10-03

Abstract Over the last decade, perovskite solar cells (PSCs) have drawn extensive attention owing to their high power conversion efficiency (single junction: 26.1%, perovskite/silicon tandem: 33.9%) and low fabrication cost. However, short lifespan of PSCs with initial still blocks practical applications. This operational instability may originate from intrinsic extrinsic degradation materials or devices. Although lifetime has been prolonged through component, crystal, defect, interface,...

10.1002/inf2.12522 article EN cc-by InfoMat 2024-02-01

Abstract Fast and ultrasensitive detection of pathogens is very important for efficient monitoring prevention viral infections. Here, we demonstrate a label‐free optical approach that uses printed nanochain assay colorimetric quantitative testing viruses. The antibody‐modified nanochains have high activity specificity which can rapidly identify target viruses directly from biofluids in 15 min, as well differentiate their subtypes. Arising the resonance induced near‐field enhancement, color...

10.1002/anie.202109985 article EN Angewandte Chemie International Edition 2021-09-08

Abstract Polymer matrix is felicitously applied into the active layer and transporting of perovskite solar cells (PSCs) to enable a stretchable function. However, chaotic deposition polymer chains main cause for inferior photoelectric performance. When PSCs are in working state, stress cannot be removed effectively due random chain deposition. The accumulation will irreversible damage PSCs. Herein, structural bionics patterned‐meniscus coating technology combined print chain‐oriented Based...

10.1002/adfm.202301043 article EN Advanced Functional Materials 2023-03-16

Because they exhibit important biological functions, from unfolding proteins to activating enzymes controlling cell fates, aggregates of small molecules are able serve as functional molecular entities in cellular environments. However, the inability precisely control their production has hampered understanding and exploration functions. Here we show that well-established ligand–receptor interaction between vancomycin d-Ala-d-Ala catalyzes aggregation a d-Ala-d-Ala-containing peptide...

10.1021/ja5100417 article EN publisher-specific-oa Journal of the American Chemical Society 2014-12-18

This letter reports the first 2D self-assembly of ABC miktoarm star terpolymers based on dual-responsive polycaprolactone-arm-poly(N-isopropylacrylamide)-arm-poly(2-dimethylaminoethyl methacrylate) (μ-CID), which self-assembled into multilayer nanosheets comprising polycaprolactone single crystals in tetrahydrofuran (THF)/methanol mixed solvents. Interestingly, showed pH-responsive morphological transitions aqueous solutions, yielding multidimensional assemblies, including hexagonal...

10.1021/acsmacrolett.7b00031 article EN ACS Macro Letters 2017-03-30

As one of the most important components in rotating machinery, if bearings fail, serious disasters may occur. Therefore, remaining useful life (RUL) prediction is great significance. Health indicator (HI) construction and early fault detection play a crucial role data-driven RUL prediction. Unfortunately, existing HI methods require prior knowledge preset trends, making it difficult to reflect actual degradation trend bearings. And rely on massive historical data, yet manual annotation...

10.3390/machines12060362 article EN cc-by Machines 2024-05-23

Autofocus is necessary for high-throughput and real-time scanning in microscopic imaging. Traditional methods rely on complex hardware or iterative hill-climbing algorithms. Recent learning-based approaches have demonstrated remarkable efficacy a one-shot setting, avoiding modifications mechanical lens adjustments. However, this paper, we highlight significant challenge that the richness of image content can significantly affect autofocus performance. When sparse, previous methods, whether...

10.48550/arxiv.2502.06452 preprint EN arXiv (Cornell University) 2025-02-10

Photofragmentation (PF) and subsequent nitric oxide (NO) laser-induced fluorescence (LIF) is being developed to measure the concentration of energetic materials (EM's) in soil other media. Laser radiation near 226 nm photodissociates gas-phase EM NO(2), which predissociates into NO that gives an intense luminescence. The inferred from intensity fluorescence. We have studied factors affect PF-LIF signal intensity, including effect buffer gas on LIF spectrum pure NO, 2,4,6-trinitrotoluene...

10.1364/ao.35.003998 article EN Applied Optics 1996-07-20

ABSTRACT Solution self‐assembly of amphiphilic “rod‐coil” copolymers, especially linear block copolymers and graft (also referred to as polymer brushes), has attracted considerable interest, replacing one the blocks a coil‐coil copolymer with rigid segment results in distinct features compared those copolymer. The unique interplay between microphase separation rod coil great geometric disparities can lead formation unusual morphologies that are distinctly different from known for copolymers....

10.1002/pola.28517 article EN Journal of Polymer Science Part A Polymer Chemistry 2017-02-15

Quasi-two-dimensional (quasi-2D) perovskites with a multiple quantum well structure can enhance the exciton binding energy and controllable confine effect, which are attractive materials for efficient perovskite light-emitting diodes (PeLEDs). However, multiphase mixtures contained in these would cause nonradiative recombination at film surface. Here, facile solution surface treatment is adopted to improve of quasi-2D emitting layer, reduce influence defectinduced electric-field-induced...

10.1021/acsami.9b10186 article EN ACS Applied Materials & Interfaces 2019-12-27

In this study, peptide-based self-assembled nanosheets with a thickness of approximately 1 nm were prepared using hierarchical covalent physical fabrication strategy. The alternating polymerization helical peptide E3 an azobenzene (AZO) structure yielded copolymers CoP(E3-AZO), which physically into ultrathin in unanticipated two-dimensional horizontal monolayer arrangement. This special arrangement enabled the to be equal cross-sectional diameter single linear copolymer, is rare phenomenon....

10.1002/anie.202405765 article EN Angewandte Chemie International Edition 2024-05-09

We synthesized a series of "rod–coil" graft copolymers containing laterally expanded poly-p-phenylene (PPP) backbone grafted with nonionic poly(ethylene oxide) (PEO) or ionic poly(acrylic acid) (PAA) side chains (denoted as PPP-g-PEO PPP-g-PAA). The effect the on self-assembly in THF–water mixed solvents was investigated. exhibited temperature-dependent behavior, which is affected by grafting percentage (GP) and degree polymerization (DP) PEO. At 25 °C, higher than crystallization...

10.1021/acs.macromol.7b02002 article EN Macromolecules 2017-12-28
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