A5002040596- Infectious Diseases and Tuberculosis
- Bacterial Infections and Vaccines
- Tuberculosis Research and Epidemiology
- Lymphoma Diagnosis and Treatment
- Cardiac tumors and thrombi
- Neuroinflammation and Neurodegeneration Mechanisms
- Lung Cancer Research Studies
- Orthopedic Infections and Treatments
- Lung Cancer Treatments and Mutations
- Neurogenesis and neuroplasticity mechanisms
- Stress Responses and Cortisol
- Memory and Neural Mechanisms
- CNS Lymphoma Diagnosis and Treatment
- Alzheimer's disease research and treatments
- Innovations in Medical Education
- Radiology practices and education
- Nerve injury and regeneration
- Surgical Simulation and Training
- Neuroscience and Neuropharmacology Research
- Lung Cancer Diagnosis and Treatment
Peking University
2024
Southern Medical University
2018-2024
Nanfang Hospital
2021-2023
Zhujiang Hospital
2018-2019
<title>Abstract</title> Background Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons (DANs), leading to motor dysfunction, while current treatments fail restore neuronal loss. Reprogramming astrocytes into induced DANs small molecules offers a promising therapeutic strategy, but existing methods face challenges including low efficiency and complex mechanisms. PT109B, novel multi-kinase inhibitor, has demonstrated neurogenic synaptogenic potential in...
Abstract Purpose The current study was carried out to compare the effectiveness and safety of different ALK inhibitors in treating + NSCLC . Methods Progression‐free survival ( PFS ), disease control rate DCR overall response ORR intracranial have been aggregated appraise each i. discontinuation due adverse events AE s) pooled evaluate their safety. Bayesian network meta‐analyses were used , patients treated with alectinib, ceritinib, crizotinib, chemotherapy. Results Compared chemotherapy,...
Abstract With the increasing number of medical students and scattered host hospitals, traditional clinical internship management system has been falling behind. Thus, we have independently developed a new practice based on browser/server structure. We aim to evaluate efficacy quality survey users’ satisfaction. This study was conducted Second Clinical Medical College Southern University, including 672 interns (non-user group) who had not used 315 users (user group). analyzed scores their...
Our recent study demonstrated that knockout of microRNA-301a attenuates migration and phagocytosis in macrophages. Considering macrophages Schwann cells synergistically clear the debris degraded axons myelin during Wallerian degeneration, which is a prerequisite for nerve regeneration, we hypothesized regulates degeneration regeneration via impacts on cell phagocytosis. Herein, found low expression intact sciatic nerves, with no impact structure function. By contrast, significant...
Background: This study aimed to validate the value of tuberculostearic acid (TBSA) whether it could implicate existence Mycobacterium tuberculosis (Mtb) and assist for clinical diagnosis tuberculous meningitis (TBM). Methods: The patient's cerebrospinal fluid (CSF) specimen was collected through lumbar puncture detected TBSA with gas chromatography/mass spectrometry. At same time, gold standard tests, i.e., CSF direct culture, smear microscopy, or nucleic amplification Mtb were routinely...
The conventional confirmation tests of tuberculous meningitis (TBM) are usually low in sensitivity, leading to high TBM mortality. Hence, sensitive methods for indicating the presence bacilli required. Tuberculostearic acid (TBSA), a constituent from Mycobacterium tuberculosis had been evaluated as promising marker, but fails demonstrate consistent results definite TBM. This study retrospectively reviewed medical records 113 suspects, constructing TBSA-combined scoring system based on...
Abstract This study aimed to validate the value of tuberculostearic acid (TBSA) whether it could implicate existence M. tuberculosis and assist for clinical diagnosis Tuberculous Meningitis (TBM). Gas Chromatography/mass spectrometry was used detect TBSA in chemically pretreated cerebrospinal fluid suspected TBM patients. In total, 140 patients were admitted our included 27 confirm 50 positive Sensitivity 0.7407 (CI 95%: 0.5372-0.8889) specificity 0.7345 0.6432-0.8132) calculated. The Lancet...