A5100762869- Influenza Virus Research Studies
- Viral gastroenteritis research and epidemiology
- Cancer survivorship and care
- Respiratory viral infections research
- Antimicrobial Resistance in Staphylococcus
- Antibiotics Pharmacokinetics and Efficacy
- Geotechnical Engineering and Analysis
- Family Support in Illness
- Grouting, Rheology, and Soil Mechanics
- Hepatitis Viruses Studies and Epidemiology
- Geotechnical Engineering and Underground Structures
- Wnt/β-catenin signaling in development and cancer
- Vector-borne infectious diseases
- Palliative Care and End-of-Life Issues
- SARS-CoV-2 and COVID-19 Research
- Health and Wellbeing Research
- Orthopaedic implants and arthroplasty
- Sirtuins and Resveratrol in Medicine
- Asphalt Pavement Performance Evaluation
- Cancer-related gene regulation
- Mosquito-borne diseases and control
- Osteoarthritis Treatment and Mechanisms
- Biochemical Analysis and Sensing Techniques
- Vaccine Coverage and Hesitancy
- Neurosurgical Procedures and Complications
Jeonbuk National University
2015-2024
Yonsei University
2003-2024
Gangnam Severance Hospital
2024
Severance Hospital
2024
Hallym University Dongtan Sacred Heart Hospital
2023-2024
Gangneung–Wonju National University
2024
Korea Testing Laboratory
2023
Wooridul Hospital
2023
Jeonbuk Development Institute
2011-2021
Chonbuk National University Hospital
2012-2020
Background The transmission mode of severe acute respiratory syndrome coronavirus 2 is primarily known as droplet transmission. However, a recent argument has emerged about the possibility airborne On June 17, there was disease 2019 (COVID-19) outbreak in Korea associated with long distance Methods epidemiological investigation implemented based on personal interviews and data collection closed-circuit television images, cell phone location data. epidemic support system developed by Disease...
Abstract Bioactive titanium metal can be prepared by NaOH and heat treatments that present the with a graded bioactive surface layer of amorphous sodium titanate. This study used laser electrophoresis together transmission electron microscopy (TEM) energy‐dispersive X‐ray microanalysis (EDX) to relate potential change its structural in simulated body fluid (SBF). The was highly negative immediately after immersion SBF. With increasing soaking time, increased, revealing maximum positive...
Tumor-infiltrating immune cells perform a crucial function in host reactions against diffuse large B-cell lymphoma (DLBCL). In this study, we have identified subset of tumor-infiltrating FOXP3-positive regulatory T (Tregs) the initial DLBCL biopsy specimens, and evaluated their prognostic significance. Ninety six patients with were retrospectively. The pattern FOXP3 protein expression was using standard immunohistochemistry paraffin-embedded tissue samples. Sixty seven all 96 specimens...
Abstract Expanding the exercise capacity of skeletal muscle is an emerging strategy to combat obesity-related metabolic diseases and this can be achieved by shifting fibers toward slow-twitch oxidative type. Here, we report that Sirt6, anti-aging histone deacetylase, critical in regulating myofiber configuration type Sirt6 activator mimetic. Genetic inactivation reduced while its transgenic overexpression increased mitochondrial performance mice. Mechanistically, show downregulated Sox6, a...
Recently, the roles of SIRT1 and deleted in breast cancer 1 (DBC1) human have been extensively studied it has demonstrated that they are involved many carcinomas. However, their clinical significance for soft-tissue sarcomas not examined. In this study, we evaluated expression prognostic SIRT1, DBC1, P53, β-catenin, cyclin D1, KI67 104 cases sarcomas.Immunohistochemical D1 were seen 71%, 74%, 53%, 48%, 73% sarcomas, respectively. The significantly correlated with advanced clinicopathological...
Identification of specific needs in patients with cancer is very important for the provision patient-centered medical service. The aim this study was to investigate unmet and related factors Korean breast survivors. A multicenter, cross-sectional, interview survey performed among 332 Comprehensive Needs Assessment Tool administered survivors who gave written informed consent participate. Data were analyzed using t-test, ANOVA multiple regression analysis. level highest domain ‘Information...
Background: Unintended secondary changes in the posterior tibial slope (PTS) and torsion angle (TTA) may occur after medial open-wedge high osteotomy (MOWHTO). In surgical procedures using patient-specific instruments (PSIs), it is essential to reproduce PTS TTA that were planned simulations. Purpose: To analyze factors causing unintended sagittal axial alignment MOWHTO. Study Design: Case series; Level of evidence, 4. Methods: Overall, 63 patients (70 knees) who underwent MOWHTO a PSI...
Abstract Stress that impairs endoplasmic reticulum (ER) function leads to an accumulation of unfolded or misfolded proteins in the ER (ER stress). Autophagy is a lysosomal pathway involved turnover cellular macromolecules and organelles, which emerging data indicate stress also potent inducer autophagy. autophagy are human cancer. We examined expression stress‐related [GRP78 C/EBP homologous protein (CHOP)] autophagic (Beclin‐1 LC3) non‐small cell lung carcinomas (NSCLCs), bronchioloalveolar...
Lipocalin 2 ( LCN 2), a member of the lipocalin superfamily, plays an important role in oncogenesis and progression various types cancer. However, expression pattern functional colorectal cancer CRC ) is still poorly understood. The purpose present study was to investigate whether associated with proliferation epithelial–mesenchymal transition EMT elucidate underlying signaling pathways. preferentially expressed cells compared normal tissues. significantly lower metastatic or advanced‐stage...
Severe fever with thrombocytopenia syndrome (SFTS) is an acute, febrile, and potentially fatal tick-borne disease caused by the SFTS Phlebovirus. Here, we evaluated effects of steroid therapy in Korean patients SFTS.A retrospective study was performed a multicenter clinical cohort from 13 university hospitals between 2013 2017. We survival analysis using propensity score matching 142 diagnosed genetic or antibody tests.Overall fatality rate 23.2%, 39.7% among 58 who underwent therapy....
As part of a study to develop load and resistance factor design (LRFD) codes for foundation structures in South Korea, factors the static bearing capacity driven steel pipe piles were calibrated framework reliability theory. A database 52 test results was compiled, data from these sorted into two cases: standard penetration (SPT) N-value at pile tip (i) less than 50 (ii) equal or more 50. Reliability analyses calibration analysis methods adopted Korean Design standards performed using...
Korean Red Ginseng (KRG) is a functional food and has been well known for keeping good health due to its anti-fatigue immunomodulating activities. However, there no data on red ginseng preventive activity against acute respiratory illness (ARI). The study was conducted in randomized, double-blinded, placebo-controlled trial healthy volunteers (Clinical Trial Number: NCT01478009). Our primary efficacy end point the number of ARI reported secondary severity symptoms, duration ARI. A total 100...
Diet-induced obesity and consequent insulin resistance are caused, in part, by macrophage polarization accumulation peripheral tissues. Here, we examined the effects of endogenously synthesized n-3 PUFAs on chemotaxis polarization.Fat-1 mice wild-type (WT) littermates were fed a 60% calorie high-fat diet (HFD) for 10 weeks. Bone marrow macrophages (BMMs) from fat-1 WT used vitro assays studies. HFD exhibited glucose intolerance, resistance, lipid infiltration liver adipose tissue. However,...
Abstract With the number of cellular phone users rapidly increasing, there is a considerable amount public concern regarding effects that electromagnetic fields (EMFs) from phones have on health. People with self‐attributed hypersensitivity (EHS) complain subjective symptoms such as headaches, insomnia, and memory loss, attribute these to radio frequency (RF) radiation and/or base stations. However, EHS difficult diagnose because it relies person's judgment. Various provocation studies been...