A5072173977- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Heart Failure Treatment and Management
- Infective Endocarditis Diagnosis and Management
- Cardiac Valve Diseases and Treatments
- Cardiovascular Health and Disease Prevention
- Transplantation: Methods and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac Structural Anomalies and Repair
- Chemotherapy-induced cardiotoxicity and mitigation
- Congenital Heart Disease Studies
- Viral Infections and Immunology Research
- Venous Thromboembolism Diagnosis and Management
- Ultrasound in Clinical Applications
- Blood Pressure and Hypertension Studies
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Healthcare during COVID-19 Pandemic
- Cardiovascular Health and Risk Factors
- Healthcare Regulation
- Pulmonary Hypertension Research and Treatments
- Cardiac tumors and thrombi
- Glioma Diagnosis and Treatment
- Inflammatory Biomarkers in Disease Prognosis
Universidade Federal do Rio Grande do Sul
2014-2025
Hospital de Clínicas de Porto Alegre
2016-2025
Brigham and Women's Hospital
2013-2023
Hospital Universitário Antônio Pedro
2023
Universidade Federal Fluminense
2023
Harvard University
2016-2021
Hospital de Clínicas
2017
University of Minho
2017
Medical University of South Carolina
2009-2016
Universidade de Taubaté
2016
Left atrial (LA) size is an established marker of risk for adverse outcomes in heart failure with preserved ejection fraction (HFpEF). However, the independent prognostic importance LA function HFpEF not known.We assessed measured by speckle-tracking echocardiography 357 patients enrolled Treatment Of Preserved Cardiac Function Heart Failure With Aldosterone Antagonist (TOPCAT) trial who were sinus rhythm at time echocardiography. Lower peak strain, indicating dysfunction, was associated...
Atrial fibrillation (AF) is an arrhythmia causing significant symptoms and raising the risk of complications. To evaluate association clinical, electrocardiographic, echocardiographic parameters with prevalent atrial or flutter (AFF) assess profile for incident AFF using AF prediction scores CHARGE-AF EHR in elderly population from a developing country. We included all participants ELSA-Brasil aged 60 over whose diagnosis could be defined through self-report electrocardiogram who had...
Renal dysfunction is a common comorbidity in patients with heart failure and preserved ejection fraction (HFpEF). We sought to determine whether renal was associated measures of cardiovascular structure/function HFpEF. studied 217 participants from the PARAMOUNT study HFpEF who had echocardiography kidney function. evaluated relationships between [estimated glomerular filtration rate (eGFR) >30 <60 mL/min/1.73 m2 and/or albuminuria] structure/function. The mean age population 71 years, 55%...
Background— Obesity increases cardiovascular risk. However, the extent to which various measures of body composition are associated with abnormalities in cardiac structure and function, independent comorbidities commonly affecting obese individuals, is not clear. This study sought examine relationship between mass index, waist circumference, percent fat conventional advanced function. Methods Results— We studied 4343 participants ARIC (Atherosclerosis Risk Communities) who were aged 69 82...
AimsMechanical dyssynchrony has been postulated to play a pathophysiologic role in heart failure with preserved ejection fraction (HFpEF).
Background Maximal left atrial (LA) volume is reported by most echocardiography laboratories and associated with clinical outcomes in patients heart failure (HF). Recent studies suggest that minimal LA may better reflect ventricular filling pressure be more prognostic than maximal volume. This study assessed the value of indexed (LAVImin) HF preserved ejection fraction. Methods Results We relationship LAVImin a primary composite end point cardiovascular death, aborted cardiac or...
Prehypertension (blood pressure (BP) of 120–139mm Hg systolic and/or 80–89mm diastolic) is highly prevalent and associated with increased cardiovascular risk. Our goal was to investigate the extent which prehypertension end-organ alterations in cardiac structure function a large biracial cohort older men women. We studied 4,871 participants Atherosclerosis Risk Communities (ARIC) study who attended visit 5 (2011–2013) underwent two-dimensional echocardiography while free coronary heart...
Background Heart failure (HF) has a major impact on public health. HF staging helps capture preclinical disease and its progression to advanced stages. There are scarce data from longitudinal studies in Latin America. This study aimed determine the prevalence mortality of stages Brazilian adult cohort participants 60 years old over. Methods The ELSA‐Brasil (Brazilian Longitudinal Study Adult Health) multicentric comprises 15 105 adults. From 2008 2010, ELSA carried out interviews clinical,...
Background: Cardiovascular involvement is among the main features of MPS disorders and it also a significant cause morbidity mortality. The range manifestations includes cardiac valve disease, conduction abnormalities, left ventricular hypertrophy, coronary artery disease. Here, we assessed cardiovascular in cohort children adults with I, II, IV, VI, as well impact enzyme replacement therapy (ERT) on those manifestations. Methods: We performed chart review 53 23 different types that had...
High blood pressure (BP) is associated with higher rates of cardiovascular events, even in stage I hypertension (HTN) and prehypertension (preHTN). Lower left ventricular (LV) systolic function, assessed by global longitudinal strain (GLS), has been demonstrated individuals HTN compared to normal BP, but a comparison preHTN was not described date. The PREVER study includes two randomized double-blind controlled trials, performed volunteers (PREVER-prevention trial) or (PREVER-treatment...
Antihypertensive treatment improves echocardiographic parameters of hypertensive target organ damage in stage II hypertension, but less is known about the effects I hypertension.In a cohort study nested randomized double-blind trial PREVER-treatment, 2-dimensional echocardiograms were performed 110 individuals, aged 54.8 ± 7.9 years-old, with hypertension at baseline and after 18 months chlorthalidone/amiloride or losartan.At baseline, 66 (60%) participants had concentric remodeling. After...
Hypertensive heart disease (HHD) is recognized as a key clinical precursor to failure with preserved ejection fraction (HFPEF). However, pathophysiological transition from HHD HFPEF not well understood. We sought determine whether regional differences in impaired myocardial function may underlie the greater mechanical dysfunction seen compared HHD. used standardized echocardiography assess deformation cohort of n = 327 adults left ventricular (LV) (≥45%), including: 129 HFPEF, 158 and no...
A ocorrência de casos apendicite aguda causada por Schistosoma haematobium e S. mansoni é uma situação clínica que tem vindo a ser observada em doentes submetidos apendicectomia na urgência do Hospital Américo Boavida Luanda. Atendendo à prevalência morbilidade da schistosomose (ou bilharziose) no país, admitimos esta infeção parasitária seja um fator causal muito frequente apendicite, particularmente nas populações mais expostas transmissão. Descrevemos dois associada presença ovos destas...
describe cardiovascular findings from echocardiograms and electrocardiograms in patients with Classic Homocystinuria.this retrospective exploratory study evaluated fourteen subjects Homocystinuria (median age = 27.3 years; male n 8, B6-non-responsive 9 patients), recruited by convenience sampling seen Hospital de Clínicas Porto Alegre (Brazil), between January 1997 July 2020. Data on clinical findings, echocardiogram electrocardiogram were retrieved medical records.Eight presented some...
Abstract OBJECTIVES Right ventricular–pulmonary arterial (RV–PA) coupling interactions are largely unexplored in heart transplant patients. The outcome of this study was RV–PA at 7 and 30 days after its association with donor–recipient size matching. METHODS Clinical, echocardiographic haemodynamic data from a retrospective cohort recipients respective donors were reviewed. Coupling between examined by assessing the RV fractional area change pulmonary artery systolic pressure ratio....
Metabolic syndrome (MS) is associated with increased cardiovascular risk. It not clear whether myocardial changes showed in this syndrome, such as diastolic dysfunction, are due to the systemic effects of or specific effects.Compare function, biomarkers representing extracellular matrix activity (ECM), inflammation and cardiac hemodynamic stress patients MS healthy controls.MS (n = 76) controls (n=30) were submitted a clinical assessment, echocardiographic study, measurement plasma levels...