A5066515215- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Radiomics and Machine Learning in Medical Imaging
- Renal cell carcinoma treatment
- MicroRNA in disease regulation
- Cancer, Hypoxia, and Metabolism
- Infectious Diseases and Tuberculosis
- Cancer Diagnosis and Treatment
- Cancer-related gene regulation
- Medical Imaging and Pathology Studies
- Sarcoma Diagnosis and Treatment
- MRI in cancer diagnosis
- Cancer Mechanisms and Therapy
- Peptidase Inhibition and Analysis
- Liver Disease Diagnosis and Treatment
- Mycobacterium research and diagnosis
- Mast cells and histamine
- Cancer Immunotherapy and Biomarkers
- Curcumin's Biomedical Applications
- Hippo pathway signaling and YAP/TAZ
- Autoimmune Neurological Disorders and Treatments
- Diagnosis and treatment of tuberculosis
- Nutrition, Genetics, and Disease
- Gastrointestinal Tumor Research and Treatment
First Affiliated Hospital of Xinxiang Medical University
2024
Guangzhou Medical University
2024
Affiliated Hospital of Qingdao University
2014-2024
Peking University
2024
Peking University Cancer Hospital
2024
Qingdao University
2018-2024
Qingdao Women and Children's Hospital
2020-2021
Fuwai Yunnan Cardiovascular Hospital
2020-2021
Jilin University
2015-2020
Union Hospital
2016-2020
Abstract Background Cholangiocarcinoma is a common malignant tumor of digestive system. LncRNA metallothionein 1 J, pseudogene (MT1JP) has been reported to play tumor-suppressing roles in multiple cancers. However, its effect on cholangiocarcinoma not evaluated. Methods The expression MT1JP intrahepatic specimens and paired para-carcinoma tissues were detected by real-time PCR. overexpression plasmid siRNA transfected into cells change the levels MT1JP. CCK-8, flow cytometry transwell assays...
ABSTRACT Metastatic growth is the leading cause of cancer‐related death in non–small cell lung cancer (NSCLC). Metastasis believed to be initiated by an increase motility mediated loss cell–cell adhesion because suppression E‐cadherin [encoded Cadherin 1 ( CDH1 )]. However, very little known about molecular mechanism regulation. Therefore, we hypothesized that cancer—associated transcript‐1 (NSCLCAT1) suppresses functional and mediates Hippo signaling pathway, resulting increased migration...
Abstract Background To explore the molecular mechanisms of anti‐cancer effect curcumin in human lung squamous cell carcinoma ( LSQCC ) SK‐MES ‐1 cells. Methods Cell viability was determined using MTT assay. Ribonucleic acid sequencing performed to measure expression levels transcripts cells treated with 15 μmol/L (treatment groups) or an equal amount dimethylsulfoxide (control). Cuffdiff software used identify differentially expressed genes DEGs treatment groups, followed by enrichment...
The present study is to screen lymph node metastasis-related microRNAs (miRNAs) in lung adenocarcinoma (LUAD) and uncover their underlying mechanisms.The miRNA microarray dataset was collected from the Gene Expression Omnibus database under accession number GSE64859. differentially expressed miRNAs (DEMs) were identified using a t-test. Target genes of DEMs predicted through miRWalk2.0 database. function these target annotated with clusterProfiler Database for Annotation, Visualization...
Research has shown that long-chain noncoding RNAs (lncRNAs) are involved in the regulation of a variety biological processes, including peripheral nerve regeneration, part by acting as competing endogenous RNAs. c-Jun plays key role repair injury. However, precise underlying mechanism remains unclear. In this study, we performed microarray and bioinformatics analysis mouse crush-injured sciatic nerves found lncRNA Pvt1 was overexpressed Schwann cells after Mechanistic studies revealed...
Background: To evaluate the value of shear wave elastic imaging (SWE) in classification esophageal varices (EV) and detection rupture hemorrhage. Methods: A total 120 patients with clinically diagnosed cirrhosis were selected from October 2017 to 2018 underwent ultrasonography, endoscopy, laboratory examinations. Several factors, including gender, age, body mass index (BMI), aspartate aminotransferase (AST), AST platelet count ratio (APRI), portal vein diameter, count, spleen thickness,...
Abstract Chinese women have dense and small breasts. Therefore, in China, contrast ultrasound elastography are commonly used for detection of the breast lumps. Purpose study was to compare sensitivity accuracy with diagnosis A total 1000 a damp mass, pain, nipple discharge, and/or skin discharge were subjected elastography. Women stereotactic vacuum-assisted biopsy under B-mode ultrasonography (n = 750). The examinations graded on 5-points scale method. Data Chi-square Independence test at...
Background: Clear cell renal carcinoma (ccRCC) is one of the most common urological tumors, and its incidence increasing year by year. Tumor stroma ratio (TSR) can reflect amount stromal component around tumor cells, independently predict prognosis tumor. This study aims to evaluate prognostic value TSR in ccRCC patients. Methods: From January 2010 December 2015, clinical histopathological data patients with who underwent surgical operation were collected. Using (50%) as cut-off value,...
探讨管状囊性肾细胞癌（tubulocystic renal cell carcinoma，TCRCC）的临床病理学特征。
The simultaneous amplification/testing for tuberculosis (SAT-TB) targets specific 16s rRNA detecting Mycobacterium in real-time.
Aggressive angiomyxoma (AAM) is rare.AAM characterized by invasion and recurrence.Improving the detection rate of AAM through ultrasonic inspection technology.There very little literature reported on AAM.And performance rare.Therefore, this article describes ultrasound manifestation a 54-year-old woman whose pathology confirmed to be AAM, summarizes common manifestations AAM.The unique feature that does not explore typical "vortex".So we need diagnose case other findings.The patient...
Abstract Background: Cholangiocarcinoma is a common malignant tumor of digestive system. LncRNA metallothionein 1J, pseudogene (MT1JP) has been reported to play tumor-suppressing roles in multiple cancers. However, its effect on cholangiocarcinoma not evaluated. Methods: The expression MT1JP intrahepatic specimens and paired para-carcinoma tissues were detected by real-time PCR. overexpression plasmid siRNA transfected into cells change the levels MT1JP. CCK-8, flow cytometry transwell...
Objective To explore the value of 18-fluorine flurodeoxyglucose (18F-FDG) positron-emission tomography (PET)/computed (CT) in detecting recurrence and metastasis postoperative colorectal cancer patients with elevated serum carcinoembryonic antigen (CEA). Methods Clinical data 60 cases cancer, including PET/CT, pathological, follow-up results, were analyzed retrospectively. Results There 50 18F-FDG PET/CT positive 10 negative cases, 1 false 3 cases. The sensitivity, specificity,...