A5102769863- Intraocular Surgery and Lenses
- Retinal and Macular Surgery
- Traumatic Ocular and Foreign Body Injuries
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Ocular Infections and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Retinal Imaging and Analysis
- Ocular Disorders and Treatments
- Vascular Malformations Diagnosis and Treatment
- Ocular and Laser Science Research
- Corneal Surgery and Treatments
- Retinal Diseases and Treatments
- Ocular Surface and Contact Lens
- Nasolacrimal Duct Obstruction Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Bacterial Identification and Susceptibility Testing
- Ocular Oncology and Treatments
- Child Abuse and Related Trauma
- Craniofacial Disorders and Treatments
- Facial Trauma and Fracture Management
- Cancer and Skin Lesions
- Ophthalmology and Eye Disorders
- Phagocytosis and Immune Regulation
- Environmental Toxicology and Ecotoxicology
Wuhan University
2010-2024
Renmin Hospital of Wuhan University
2010-2024
Shanghai Public Security Bureau
2019
Wuhan General Hospital of Guangzhou
2016
General Hospital of Guangzhou Military Command
2016
Renmin University of China
2005
Abstract Purpose Ochratoxin A (OTA) contamination of food and feed is a serious problem worldwide. OTA considered carcinogen immunotoxic, nephrotoxic, neurotoxic mycotoxin. The present study aims to determine the toxic effects on retinal ganglion cells (RGCs) assess resulting impairment function in mice. Methods RGC-5 were exposed (100 200 μg/L) for 3 days, mice fed OTA-contain μg/kg) diets 4 weeks. Antioxidant indices detected by spectrophotometer. apoptosis was determined flow cytometry....
Suprachoroidal hemorrhage (SCH) is a rare but dangerous complication of intraocular surgery. There are some risk factors for this devastating during pars plana vitrectomy. In case, we will report the intraoperative occurrence SCH vitrectomy in traumatized eyes.Retrospective analysis five eyes with history blunt (n = 1) or penetrating 4) trauma was made. Baseline systemic and ocular characteristics, surgical procedures, time point SCH, management final visual outcomes were measured.One eye...
Abstract Purpose This paper aimed to assess the diagnostic utility of a newly developed gene-based technology-nanopore targeted sequencing (NTS) in suspected endophthalmitis patients. Methods retrospective study included 43 patients (44 eyes) with endophthalmitis. NTS was applied along microbiological culture detect unknown pathogens intraocular fluid samples. The mainly evaluated from three aspects, including positivity rate bacterial/fungal presence, turnaround time and frequency change...
Purpose To characterize features of central retinal artery occlusion (CRAO) using multicolor (MC) imaging and to assess the differences in CRAO grading between color fundus photography (CFP) MC image qualitatively quantitatively. Methods We conducted a prospective, cross-sectional study Department Ophthalmology Renmin Hospital Wuhan University. In total, 86 acute patients were included. Spectral-domain optical coherence tomography (SD-OCT), CFP, examinations taken at baseline. Based on...
Acute retinal ischemia and ischemia-reperfusion injury are the primary causes of neural cell death vision loss in artery occlusion (RAO). The absence an accurate mouse model for simulating ischemic process has hindered progress developing neuroprotective agents RAO. We developed a unilateral pterygopalatine ophthalmic (UPOAO) using silicone wire embolization combined with carotid ligation. survival ganglion cells visual function were evaluated to determine duration ischemia....
To determine (i) the etiology, epidemiology, mechanism of injury, and risk factors associated with open globe injuries (OGIs) in children (ii) visual outcomes pediatric patients post-traumatic endophthalmitis following 23-gauge pars plana vitrectomy (PPV) combined silicone oil tamponade (SOT).A total 107 consecutive patients, <15 years age, who had been diagnosed between September 2009 October 2015, were included this 6-year retrospective study. All undergone a PPV SOT procedure. We reviewed...
A 38-year-old male presented with a 2-week history of sudden blurred vision (best-corrected visual acuity: 20/200) and pain in his right eye. Spectral domain optical coherence tomography (OCT) revealed focal thickening the retinal pigment epithelium layer as leopard spots [Fig. 1a]. Fundus examination demonstrated exudative detachment vascular dilation 1c] whereas contralateral eye remained unremarkable 1b d]. B-scan ultrasonography showed short axial length (17.3 mm). fluorescein...
As a vitreous substitute for long-term tamponade, silicone oil is widely used in vitreoretinal surgery to treat retinal detachment with proliferative vitreoretinopathy and some internal reconstruction after globe trauma.The aim of this study was compare the changes visual acuity, axial length, refraction eyes before removal intraocular 2 different viscosities reattachment surgery. The difference final anatomic success (stable reattachment) rate also assessed.Patients surgically reattached...
Abstract To evaluate the predictive and prognostic value of fibroblast growth factor 21 (FGF21) levels in retinal artery occlusion (RAO) patients. In this case–control study, serum FGF21 were detected by using ELISA method. Multivariable logistic regression analyses performed to significance assessing risk developing RAO its impact on vision concurrent ischemic stroke. Compared with control group, significantly higher (median [IQR] = 230.90[167.40,332.20] pg/ml) Multivariate analysis showed...
Acute retinal ischemia and ischemia-reperfusion injury are primary causes of neural cell death vision loss in artery occlusion (RAO). The absence an accurate mouse model simulating the ischemic process has hampered progress developing neuroprotective agents for RAO. A unilateral pterygopalatine ophthalmic (UPOAO) was developed by employing silicone wire embolization combined with carotid ligation. survival ganglion cells visual function were evaluated to determine duration....
Nanopore targeted sequencing showed a higher positivity rate and shorter turnaround time than did traditional culture in identifying pathogens the intraocular fluid samples of patients with endogenous endophthalmitis.To evaluate feasibility clinical application nanopore (NTS) for identification endophthalmitis, especially those fungus-associated endophthalmitis.In this retrospective study, medical records etiological results 27 (34 eyes) endophthalmitis were reviewed. The examined using both...