Jarosław Grobelny

ORCID: 0000-0003-2648-2186
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About
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Research Areas
  • Force Microscopy Techniques and Applications
  • Nanoparticles: synthesis and applications
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Molecular Junctions and Nanostructures
  • Adhesion, Friction, and Surface Interactions
  • Magnetic properties of thin films
  • Electrochemical Analysis and Applications
  • Legionella and Acanthamoeba research
  • Ocular Surface and Contact Lens
  • Conducting polymers and applications
  • Advanced Nanomaterials in Catalysis
  • Magnetic Properties of Alloys
  • Diamond and Carbon-based Materials Research
  • Surface Modification and Superhydrophobicity
  • Herpesvirus Infections and Treatments
  • Ocular Infections and Treatments
  • Advanced Sensor and Energy Harvesting Materials
  • TiO2 Photocatalysis and Solar Cells
  • Advanced biosensing and bioanalysis techniques
  • ZnO doping and properties
  • Advanced Photocatalysis Techniques
  • Electrohydrodynamics and Fluid Dynamics
  • Cytomegalovirus and herpesvirus research
  • Microplastics and Plastic Pollution
  • Nanofabrication and Lithography Techniques

University of Łódź
2016-2025

Lodz University of Technology
2003-2023

Faculty (United Kingdom)
2020-2021

Materials Technology (United Kingdom)
2014

National Institute of Standards and Technology
2006-2010

National Institute of Standards
2008

Environmental Protection Engineering (Greece)
2004

Dynamic light scattering is a method that depends on the interaction of with particles. This can be used for measurements narrow particle size distributions especially in range 2–500 nm. Sample polydispersity distort results, and we could not see real populations particles because big presented sample screen smaller ones. Although theory mathematical basics DLS technique are already well known, little has been done to determine its limits experimentally. The distribution artificially...

10.1155/2013/313081 article EN cc-by Journal of Nanomaterials 2013-01-01

We describe herein the significance of a sodium citrate and tannic acid mixture in synthesis spherical silver nanoparticles (AgNPs). Monodisperse AgNPs were synthesized via reduction nitrate using two chemical agents: acid. The shape, size distribution particles determined by UV-Vis spectroscopy, dynamic light scattering (DLS) scanning transmission electron microscopy (STEM). Special attention is given to understanding experimentally confirming exact role reagents (sodium present reaction...

10.1007/s11051-017-3973-9 article EN cc-by Journal of Nanoparticle Research 2017-08-01

We made comparison of titanium dioxide powders obtained from three syntheses including sol‐gel and precipitation methods as well using layered (tetramethyl)ammonium titanate a source TiO 2 . The precursors were subjected to step annealing at elevated temperatures transform into rutile form. transformation was determined by Raman measurements in each case. resulting products characterised spectroscopy dynamic light scattering. main goal the studies performed compare temperature titania...

10.1155/2014/124814 article EN cc-by Journal of Nanomaterials 2014-01-01

The interaction between silver nanoparticles and herpesviruses is attracting great interest due to their antiviral activity possibility use as microbicides for oral anogenital herpes. In this work, we demonstrate that tannic acid modified sized 13 nm, 33 nm 46 are capable of reducing HSV-2 infectivity both in vitro vivo. was size-related, required direct blocked virus attachment, penetration further spread. All tested reduced infection inflammatory reaction the mouse model when used at or a...

10.1371/journal.pone.0104113 article EN cc-by PLoS ONE 2014-08-12

Silver nanoparticles (AgNPs) have been shown to promote wound healing and exhibit antimicrobial properties against a broad range of bacteria. In our previous study, we prepared tannic acid (TA)-modified AgNPs showing good toxicological profile immunomodulatory useful for potential dermal applications.In this in vitro scratch assay, tests, modified lymph node assay as well mouse splint model were used access the TA-modified unmodified AgNPs.TA-modified but not exhibited effective...

10.2147/ijn.s154797 article EN cc-by-nc International Journal of Nanomedicine 2018-02-01

(1) Background: Tannic acid is a plant-derived polyphenol showing antiviral activity mainly because of an interference with the viral adsorption. In this work, we tested whether modification silver nanoparticles tannic (TA-AgNPs) can provide microbicide additional adjuvant properties to treat genital herpes infection. (2) Methods: The mouse model vaginal simplex virus 2 (HSV-2) infection was used test immune responses after treatment primary TA-AgNPs, and later, re-challenge virus. (3)...

10.3390/v10100524 article EN cc-by Viruses 2018-09-26

Mucoadhesive gelling systems with tannic acid modified silver nanoparticles were developed for effective treatment of herpes virus infections. To increase nanoparticle residence time after local application, semi solid formulations designed from generally regarded as safe (GRAS) excipients investigated their rheological and mechanical properties followed ex vivo mucoadhesive behavior to the porcine vaginal mucosa. Particular effort was made evaluate activity nanoparticle-based hydrogels...

10.3390/ijms19020387 article EN International Journal of Molecular Sciences 2018-01-28

(1) Background: Lactoferrin has been recognized as a potent inhibitor of human herpetic viruses, such herpes simplex type 1 (HSV-1) and 2 (HSV-2). In this work, we tested if silver gold nanoparticles modified with lactoferrin (LF-Ag/AuNPs) can become novel microbicides additional adjuvant properties to treat genital infection. (2) Methods: The antiviral cytotoxic activities LF-Ag/AuNPs were in skin HaCaT vaginal VK-2-E6/E7 keratinocytes. Viral titers immune responses after treatment murine...

10.3390/microorganisms10010110 article EN cc-by Microorganisms 2022-01-05

Polyphenols possess antioxidant, anti-inflammatory and antimicrobial properties have been used in the treatment of skin wounds burns. We previously showed that tannic acid-modified AgNPs sized >26 nm promote wound healing, while 13 can elicit strong local inflammatory response. In this study, we tested bimetallic Au@AgNPs 30 modified with selected flavonoid non-flavonoid compounds for healing applications.Bimetallic were obtained by growing an Ag layer on AuNPs further polyphenols. After...

10.2147/ijn.s252027 article EN cc-by-nc International Journal of Nanomedicine 2020-07-01

Transition metal oxides have garnered attention for the methanol electro‐oxidation reaction owing to their easy availability, high catalytic applicability, and multiple oxidation capabilities. Bimetal‐based catalysts further enhance performance of reaction. In this context, a chrysanthemum‐flower‐like MoO 2 /WO 3 is synthesized through solvothermal annealing strategy. The morphology attests rough surface pores in catalyst, augmenting its area reactions enhancing applicability....

10.1002/ente.202400075 article EN Energy Technology 2024-04-24

Free-living amoebae belonging to Acanthamoeba genus are widely distributed protozoans which able cause infection in humans and other animals such as keratitis encephalitis. is a vision-threatening corneal with currently no available fully effective treatment. Moreover, the therapeutic options insufficient very toxic eye. Therefore, there an urgent need for development of more anti-amoebic agents. Nanotechnology approaches have been recently reported be useful elucidation antimicrobial,...

10.1007/s00436-018-6049-6 article EN cc-by Parasitology Research 2018-08-15

Superhydrophobic surfaces were obtained by superposition of microstructure—defined replication laser micromachined masters, with nanostructure—created durable epoxy/ γ ‐Al 2 O 3 nanoparticle composite, used for replication. Hierarchical surface topography thus consisted hexagonally spaced microcavities and agglomerates, exposed on the replica radio frequency (RF) air plasma etching. Surface was further enhanced rims around microcavity edges, resulting from nanosecond micromachining defects...

10.1155/2014/547895 article EN Journal of Nanomaterials 2014-01-01

In this paper, we discuss the influence of ligand type present on surface silver nanoparticles (AgNPs) its affinity to virus and virucidal activity against herpes simplex 2 (HSV-2). We selected four different ligands, which potentially exhibit HSV-2 used them for functionalization AgNPs: i) sodium citrate: ii) tannic acid; iii) 1-mercaptoundecane-1-sulfonate (MUS); iv) poly(ethylene glycol) (PEG). The antiviral was performed by in vitro Vero cell culture. Anti- inflammatory measurement NF-κB...

10.2147/ijn.s496050 article EN cc-by-nc International Journal of Nanomedicine 2025-03-01

Introduction: Herpes simplex virus type 1 (HSV-1) causes recurrent infections of skin and mucosal tissues with high global prevalence. HSV-1 also invades the nervous system where it establishes a lifelong latency-making infection poorly treatable We previously showed that both tannic acid-modified silver gold nanoparticles (TA-Ag/AuNPs) inhibit in vitro. Methods: used an vitro vivo model to study how metal type, size acid modification can influence development early innate response mounting...

10.2147/ijn.s512509 article EN cc-by International Journal of Nanomedicine 2025-04-01

Nanogels of poly(acrylic acid) have been synthesized using a new method, based on intramolecular cross-linking linear macromolecules in aqueous solution, induced by short (a few microseconds) pulses fast electrons. Simultaneous generation number carbon-centered radicals along the polymer chain results predominantly recombination, with only minor contribution intermolecular cross-link formation and scission. This method allows synthesis nanogels pure system consisting water, absence monomers,...

10.1021/ma021628s article EN Macromolecules 2003-03-05

Adhesion forces between a gold sphere and flat substrate are studied using atomic force microscopy in different environments. The pull-off measured vacuum is found to be small fraction of that ambient air or nitrogen atmosphere. Calculations capillary condensation forces, including the effects elastic deformation contacting bodies adsorption layers, reveal meniscus dominant source observed difference forces. experimental data show purge does not eliminate contribution force.

10.1063/1.2181200 article EN Applied Physics Letters 2006-02-27

Silver nanoparticles (AgNPs) are promising new antimicrobial agents against a wide range of skin and mucosal pathogens. However, their interaction with the immune system is currently not fully understood. Dendritic cells (DCs) crucial during development T cell-specific responses bacterial viral We have previously shown that tannic acid-modified silver (TA-AgNPs) consist microbicide HSV-2. The aim this study was to compare ability TA-AgNPs or TA-AuNPs similar sizes (TA-Ag/AuNPs) induce DCs...

10.3389/fimmu.2018.01115 article EN cc-by Frontiers in Immunology 2018-05-22

The method of TiO2-anatase film preparation on cotton and viscose fabric surfaces using the sol-gel process microwave treatment is presented. Microwave was used to change amorphous TiO2 form anatase directly fabrics. influence conditions obtainable polymorphic examined. Fabrics were pretreated with low-temperature air plasma (30 min). root mean square height in selected area increased from 44 166 nm (cotton) 9 112 (viscose). Infrared analysis showed new band at 1748 1732 cm−1 corresponding...

10.1007/s10570-016-0916-z article EN cc-by Cellulose 2016-03-28
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