Rotem Botvinik‐Nezer
A5017408286- Functional Brain Connectivity Studies
- Neural and Behavioral Psychology Studies
- Meta-analysis and systematic reviews
- Memory and Neural Mechanisms
- Olfactory and Sensory Function Studies
- Mental Health Research Topics
- Scientific Computing and Data Management
- Decision-Making and Behavioral Economics
- Behavioral Health and Interventions
- Pain Management and Placebo Effect
- Neuroscience and Music Perception
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Sensory Analysis and Statistical Methods
- Advanced Neuroimaging Techniques and Applications
- Health, Environment, Cognitive Aging
- COVID-19 and Mental Health
- Advanced MRI Techniques and Applications
- Acupuncture Treatment Research Studies
- Long-Term Effects of COVID-19
- Electoral Systems and Political Participation
- Pain Mechanisms and Treatments
- Conferences and Exhibitions Management
- Multisensory perception and integration
- Cell Image Analysis Techniques
- Corruption and Economic Development
Hebrew University of Jerusalem
2023-2024
Dartmouth Hospital
2021-2024
Dartmouth College
2019-2024
Tel Aviv University
2017-2021
Academic College of Tel Aviv-Yafo
2019
Summary Data analysis workflows in many scientific domains have become increasingly complex and flexible. To assess the impact of this flexibility on functional magnetic resonance imaging (fMRI) results, same dataset was independently analyzed by 70 teams, testing nine ex-ante hypotheses. The analytic approaches is exemplified fact that no two teams chose identical to analyze data. This resulted sizeable variation hypothesis test even for whose statistical maps were highly correlated at...
Any large dataset can be analyzed in a number of ways, and it is possible that the use different analysis strategies will lead to results conclusions. One way assess whether obtained depend on strategy chosen employ multiple analysts leave each them free follow their own approach. Here, we present consensus-based guidance for conducting reporting such multi-analyst studies, discuss how broader adoption approach has potential strengthen robustness conclusions from analyses datasets basic...
Abstract Drug treatments for pain often do not outperform placebo, and a better understanding of placebo mechanisms is needed to improve treatment development clinical practice. In large-scale fMRI study ( N = 392) with pre-registered analyses, we tested whether analgesic modulates nociceptive processes, its effects generalize from conditioned unconditioned modalities. Placebo caused robust analgesia in thermal that generalized mechanical pain. However, did decrease pain-related activity...
Abstract As the global health crisis unfolded, many academic conferences moved online in 2020. This move has been hailed as a positive step towards inclusivity its attenuation of economic, physical, and legal barriers effectively enabled individuals from groups that have traditionally underrepresented to join participate. A number studies outlined how moving made it possible gather more community increased opportunities for with various constraints, e.g., caregiving responsibilities. Yet,...
The coronavirus disease 2019 (COVID-19) outbreak introduced unprecedented health-risks, as well pressure on the economy, society, and psychological well-being due to response outbreak. In a preregistered study, we hypothesized that intense experience of potentially induced stress-related brain modifications in healthy population, not infected with virus. We examined volumetric changes 50 participants who underwent MRI scans before after COVID-19 lockdown Israel. Their were compared those...
Abstract Current noninvasive methods to detect structural plasticity in humans are mainly used study long‐term changes. Diffusion magnetic resonance imaging (MRI) was recently proposed as a novel approach reveal gray matter changes following spatial navigation learning and object‐location memory tasks. In the present work, we diffusion MRI investigate short‐term neuroplasticity that accompanies motor sequence learning. Following 45‐min training session which participants learned accurately...
There is an ongoing debate about the replicability of neuroimaging research. It was suggested that one main reasons for high rate false positive results many degrees freedom researchers have during data analysis. In Neuroimaging Analysis Replication and Prediction Study (NARPS), we aim to provide first scientific evidence on variability across analysis teams in neuroscience. We collected fMRI from 108 participants two versions mixed gambles task, which often used study decision-making under...
Recent findings show that preferences for food items can be modified without external reinforcements using the cue-approach task. In task, mere association of item images with a neutral auditory cue and speeded button press, resulted in enhanced associated stimuli. series 10 independent samples total 255 participants, we first time this non-reinforced method enhance faces, fractals affective images, as well snack foods, auditory, visual even aversive cues. This change was highly durable...
Abstract Placebo analgesia is a replicable and well-studied phenomenon, yet it remains unclear to what degree includes modulation of nociceptive processes. Some studies find effects consistent with effects, but meta-analyses show that these are often small. We analyzed placebo in large fMRI study (N = 392), including on brain responses noxious stimuli. treatment caused robust both conditioned thermal unconditioned mechanical pain. did not decrease activity pain regions, the Neurologic Pain...
Many-analysts studies explore how well an empirical claim withstands plausible alternative analyses of the same dataset by multiple, independent analysis teams. Conclusions from these typically rely on a single outcome metric (e.g. effect size) provided each team. Although informative about range effects in dataset, size team does not provide complete, nuanced understanding choices are related to outcome. We used Delphi consensus technique with input 37 experts develop 18-item subjective...
Regions that respond to multiple types of information ("convergence zones") are crucial for the brain generate coherent experiences and behaviors. The insular cortex, known its functional diversity, has been hypothesized be a key convergence hub, yet empirical evidence identifying how where occurs is incomplete. To address this gap, we analyzed across four task domains—somatic pain, non-somatic appetitive processes, aversive cognitive control—in large-scale Bayesian mega-analysis fMRI data...
Abstract Behavioral change studies and interventions focus on self-control external reinforcements to influence preferences. Cue-approach training (CAT) has been shown induce preference changes lasting months by merely associating items with neutral cues speeded responses. We utilized this paradigm study neural representation of preferences their modification without reinforcements. scanned 36 participants fMRI during a novel passive viewing task before, after 30 days following CAT....
The maintenance of behavioral change over the long term is essential to achieve public health goals such as combatting obesity and drug use. Previous work by our group has demonstrated a reliable shift in preferences for appetitive foods following novel non-reinforced training paradigm. In current studies, we tested whether distributing trials two consecutive days would affect immediately after well time at one-month follow-up. four three different designs an additional pre-registered...
Developing effective preference modification paradigms is crucial to improve the quality of life in a wide range behaviors. The cue-approach training (CAT) paradigm has been introduced as an tool modify preferences lasting months, without external reinforcements, using mere association images with cue and speeded button response. In current work for first time, we used fMRI faces stimuli CAT paradigm, focusing on face-selective brain regions. We found behavioral change effect immediately...
It is commonly assumed that memories contribute to value-based decisions. Nevertheless, most theories of decision-making do not account for memory influences on choice. Recently, new interest has emerged in the interactions between these two fundamental processes, mainly using reinforcement-based paradigms. Here, we aimed study role processes play preference change following nonreinforced cue-approach training (CAT) paradigm. In CAT, mere association cued items with a speeded motor response...
Abstract The COVID-19 outbreak introduced unprecedented health-risks, as well pressure on the financial, social, and psychological well-being due to response outbreak. Here, we examined manifestations of brain structure in healthy population, following initial phase pandemic Israel. We pre-registered our hypothesis that intense experience potentially induced stress-related modifications. Volumetric changes n = 50 participants who were scanned before after lockdown, compared with control...
Empirical observations of how labs conduct research indicate that the adoption rate open practices for transparent, reproducible, and collaborative science remains in its infancy. This is at odds with overwhelming evidence necessity these their benefits individual researchers, scientific progress, society general. To date, information required implementing throughout different steps a project scattered among many sources. Even experienced researchers topic find it hard to navigate ecosystem...
We present consensus-based guidance for conducting and documenting multi-analyst studies. discuss why broader adoption of the approach will strengthen robustness results conclusions in empirical sciences.
Abstract It is commonly assumed that memories contribute to value-based decisions. Nevertheless, most theories of decision-making do not account for memory influences on choice. Recently, new interest has emerged in the interactions between these two fundamental processes, mainly using reinforcement-based paradigms. Here, we aimed study role processes play preference change following non-reinforced cue-approach training (CAT) paradigm. In CAT, mere association cued items with a speeded motor...
As the global health crisis unfolded throughout world, many academic conferences moved online in 2020. This move has been hailed as a positive step towards inclusivity its attenuation of economic, physical and legal barriers effectively enabled individuals who have traditionally underrepresented to join participate. A number studies outlined how moving made it possible gather more community increased opportunities for with various constraints, e.g. caregiving responsibilities. Yet, mere...