A5064827745- Functional Brain Connectivity Studies
- Traumatic Brain Injury Research
- Multiple Sclerosis Research Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- EEG and Brain-Computer Interfaces
- Neural and Behavioral Psychology Studies
- Neural dynamics and brain function
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Olfactory and Sensory Function Studies
- Cardiac Arrest and Resuscitation
- Neurological disorders and treatments
- Neurological and metabolic disorders
- Memory and Neural Mechanisms
- Mental Health Research Topics
- Cognitive Functions and Memory
- Neonatal and fetal brain pathology
- Meta-analysis and systematic reviews
- Genetic Neurodegenerative Diseases
- Heart Rate Variability and Autonomic Control
- Cardiovascular Syncope and Autonomic Disorders
- Dementia and Cognitive Impairment Research
- Cognitive Science and Mapping
- Trauma and Emergency Care Studies
- Decision-Making and Behavioral Economics
- Stroke Rehabilitation and Recovery
Kessler Foundation
2016-2025
Rutgers, The State University of New Jersey
2016-2025
Rutgers New Jersey Medical School
2015-2024
National Multiple Sclerosis Society
2021
University of Nebraska–Lincoln
2021
Montclair State University
2021
Vita-Salute San Raffaele University
2016-2017
Cambridge University Press
2017
International Society of Nephrology
2017
Azienda Ospedaliera Sant’Antonio Abate di Gallarate
2016
Summary Data analysis workflows in many scientific domains have become increasingly complex and flexible. To assess the impact of this flexibility on functional magnetic resonance imaging (fMRI) results, same dataset was independently analyzed by 70 teams, testing nine ex-ante hypotheses. The analytic approaches is exemplified fact that no two teams chose identical to analyze data. This resulted sizeable variation hypothesis test even for whose statistical maps were highly correlated at...
The objective of this paper is to investigate the interrelationship between subjective and cognitive fatigue, information processing domain [processing speed (PS) vs. working memory (WM)], load (high low), time on task in Multiple Sclerosis (MS).Thirty-two MS participants 24 healthy controls completed experimental tasks both PS WM domains with different levels load. Subjective fatigue was measured using a visual analog scale at baseline multiple points throughout experiment.A mixed model...
We investigated differences in brain activation associated with cognitive fatigue between persons traumatic injury (TBI) and healthy controls (HCs). Twenty-two participants moderate-severe TBI 20 HCs performed four blocks of a difficult working memory task control during fMRI imaging. Cognitive fatigue, assessed before after each block, was used as covariate to assess fatigue-related activation. The group reported more than the HCs, though their performance comparable. Regarding activation,...
There is no single, standardized clinical instrument or biomarker available to categorize traumatic brain injury (TBI) severity that deemed the official gold standard for classification. Instead, current approach rely on several criteria establish severity. are a number of different classification systems in place used and these utilize indicators. Heterogeneity across introduces challenge recruitment into research studies obscures knowledge how degrees impact outcomes, thus, limiting...
The fronto-striatal network has been implicated in both fatigue, a common multiple sclerosis (MS) symptom, and goal attainment, which shown to reduce fatigue healthy individuals.To investigate whether stimulation of the through attainment (potential monetary gain) leads reduction MS control (HC) participants.In all, 14 19 participants performed gambling task during functional magnetic resonance imaging (fMRI). Participants were presented with an opportunity receive reward outcome condition...
The Stroop interference task is a cognitively demanding of executive control, cognitive ability that often impaired in patients with multiple sclerosis (MS).The aim this study was to compare effective connectivity patterns within network brain regions involved the performance between MS three disease clinical phenotypes [relapsing-remitting (RRMS), benign (BMS), and secondary progressive (SPMS)] healthy subjects.Effective analysis performed on data using novel method based causal Bayes...
New learning and memory deficits are common following traumatic brain injury (TBI). Yet few studies have examined the efficacy of retraining in TBI through most methodologically vigorous randomized clinical trial. Our previous research has demonstrated that modified Story Memory Technique (mSMT) significantly improves new multiple sclerosis.The present double-blind, placebo-controlled, trial changes cerebral activation on functional magnetic resonance imaging mSMT treatment persons with TBI....
Gulf War Illness (GWI) is a chronic, multi-symptom illness that affects approximately 25% of veterans, with cognitive fatigue as one its primary symptoms. Here, we investigated the neural networks associated in GWI by asking 35 veterans and 25 healthy control subjects to perform series fatiguing tasks while MRI scanner. Two types were assessed: state fatigue, which developed completed, trait or one's propensity experience when assessed over several weeks. Our results showed differed....
Working memory (WM) is often compromised after traumatic brain injury (TBI). A number of functional and effective connectivity studies investigated the interaction between regions during WM task performance. However, previously used tasks did not allow differentiation subprocesses such as capacity manipulation. We a novel paradigm, CapMan, to investigate associated with manipulation in individuals TBI relative healthy controls (HCs). CapMan allows independent investigation manipulation,...