- Gastroesophageal reflux and treatments
- Systemic Lupus Erythematosus Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Healthcare cost, quality, practices
- Vasculitis and related conditions
- Long-Term Effects of COVID-19
- Immunodeficiency and Autoimmune Disorders
- Healthcare Systems and Practices
- Health Systems, Economic Evaluations, Quality of Life
- Microscopic Colitis
- Chronic Disease Management Strategies
- Health, Medicine and Society
- Emergency and Acute Care Studies
- Drug-Induced Adverse Reactions
- Coenzyme Q10 studies and effects
- Sleep and Work-Related Fatigue
- Methemoglobinemia and Tumor Lysis Syndrome
- Hospital Admissions and Outcomes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Salivary Gland Disorders and Functions
- Occupational Health and Performance
- Medical Coding and Health Information
- Business Process Modeling and Analysis
- Complement system in diseases
- Respiratory and Cough-Related Research
Centre International de Recherche en Infectiologie
2021-2024
Centre Hospitalier Universitaire de Saint-Étienne
2017-2024
Université Jean Monnet
2021-2024
Inserm
2021-2024
Université Claude Bernard Lyon 1
2021-2024
Centre National de la Recherche Scientifique
2021-2024
Centre National pour la Recherche Scientifique et Technique (CNRST)
2024
Institute Cancer De La Loire Lucien Neuwirth
2017-2023
Hôpital Nord
2018-2023
Centre Hospitalier Universitaire de Grenoble
2023
Ocular immunotherapy-related adverse events (IRAEs), although rare, can be sight-threatening. Our objective was to analyze ocular IRAEs diagnosed in France from the marketing of immune checkpoint inhibitors (ICPIs) until June 2021 and review literature. We collected cases 28 patients (36 IRAEs), occurring after an average 17 weeks (±19). Forty-six percent were treated for metastatic melanoma. Anti-PD1 agents responsible 57% IRAEs. Anterior uveitis most common (44%), followed by panuveitis...
We conducted a national in-depth analysis including pharmacovigilance reports and clinical study to assess the reporting rate (RR) determine profile of polymyalgia rheumatica (PMR) giant cell arteritis (GCA) in COVID-19-vaccinated individuals. First, based on French database, we estimated RR PMR GCA cases individuals aged over 50 who developed their initial symptoms within one month receiving BNT162b2 mRNA, mRNA-1273, ChAdOx1 nCoV-19, Ad26.COV2.S vaccines. then nationwide survey gather...
Abstract Introduction Severe acute respiratory syndrome coronavirus 2 is a viral infection that can cause systemic disorders and lead to death, particularly in older people. Proton pump inhibitors (PPIs) increase the risk of enteric lung infections. Considering broad use PPIs people, potential role COVID-19 could be dramatic significance. The objective our study was evaluate link between severe Method We performed retrospective cohort study, including all patients aged ≥65, hospitalised for...
The objective of this study is twofold. First, we seek to understand the characteristics multimorbid population that needs hospital care by using all diagnoses information (ICD-10 codes) and two aggregated multimorbidity frailty scores. Second, use machine learning prediction models on these patients predict rehospitalization within 30 365 days their length stay. This was conducted 8 882 anonymized hospitalized at University Hospital Saint-Étienne. A descriptive statistical analysis...
The sudden admission of many patients with similar needs caused by the COVID-19 (SARS-CoV-2) pandemic forced health care centers to temporarily transform units respond crisis. This process greatly impacted daily activities hospitals. In this paper, we propose a two-step approach based on mining and discrete-event simulation for sizing recovery unit dedicated inside hospital. A decision aid framework is proposed help hospital managers make crucial decisions, such as hospitalization...
Type 1 Gaucher disease (GD) is a rare autosomal recessive lysosomal storage disorder caused by deficient activity of beta-glucocerebrosidase, leading to accumulation its substrate (glucosylceramide) in macrophages the reticuloendothelial system, which are then referred as cells. The most frequent symptoms asthenia, spleen and liver enlargement, bone abnormalities cytopenia due marrow infiltration. Lung involvement GD finding, it unclear whether may regress under enzyme replacement therapy...
Background: The thromboprophylactic efficacy of graduated compression stockings (GCS) has not yet been demonstrated in acutely ill medical patients, and guidelines vary considerably. Older patients appear to constitute a distinctive population presenting high risks both thrombosis bleeding. Objective: To evaluate the practices beliefs panel French geriatricians regarding GCS management aged over 75 years. Methods: A survey was designed study geriatric practice concerning use for...
A 67-year-old man was referred to our department for the onset of cutaneous lesions following venepunctures. His recent medical history included brief flu-like syndrome, persistent cough, dyspnoea, dry mouth, blurred vision and weight loss. The extensive clinical, biological radiological check-up showed signs consistent with systemic sarcoidosis: right uveitis, hypercalcemia, renal failure, inflammatory elevated levels ACE, alveolitis CD4+/CD8+ T cell ratio, hilar mediastinal...
While being the main potential beneficiaries of therapeutic fasting’s health benefits, elderly are frequently thought as too fragile to fast. The objective our survey was review knowledge, practices, and acceptability fasting in subjects aged 65 years over. From September 2020 March 2021, an online questionnaire sent over, using mailing list local organizations working field aging. mean age 290 respondents 73.8 ± 6.5 years, 75.2% were women 54.1% had higher education. Among respondents,...