- Laser-Plasma Interactions and Diagnostics
- Laser-induced spectroscopy and plasma
- Laser-Matter Interactions and Applications
- Laser-Ablation Synthesis of Nanoparticles
- Laser Design and Applications
- Advanced Fiber Laser Technologies
- Diamond and Carbon-based Materials Research
- Spectroscopy and Laser Applications
- Laser Material Processing Techniques
- Bone Tissue Engineering Materials
- Silicon Nanostructures and Photoluminescence
- Particle Accelerators and Free-Electron Lasers
- High-pressure geophysics and materials
- Particle accelerators and beam dynamics
- Additive Manufacturing and 3D Printing Technologies
- Advanced Chemical Physics Studies
- Photonic and Optical Devices
- Advanced Fiber Optic Sensors
- Magnetic confinement fusion research
- Advanced Surface Polishing Techniques
- Plasma Diagnostics and Applications
- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- Nonlinear Optical Materials Studies
- Optical Polarization and Ellipsometry
Vita-Salute San Raffaele University
2018-2025
National Institute of Optics
2014-2024
National Research Council
2014-2021
Istituto di Scienza e Tecnologie dell'Informazione "Alessandro Faedo"
2021
University of Parma
2021
Istituto Nazionale di Fisica Nucleare, Sezione di Pisa
1998-2019
Italian Institute of Technology
2010-2018
Università degli Studi di Enna Kore
2015
University of Pisa
1998-2011
National Institute for Astrophysics
2010
Abstract This report presents the conceptual design of a new European research infrastructure EuPRAXIA. The concept has been established over last four years in unique collaboration 41 laboratories within Horizon 2020 study funded by Union. EuPRAXIA is first project that develops dedicated particle accelerator based on novel plasma acceleration concepts and laser technology. It focuses development electron accelerators underlying technologies, their user communities, exploitation existing...
Abstract Many factors contribute to the poor axonal regrowth and ineffective functional recovery after spinal cord injury (SCI). Biomaterials have been used for SCI repair by promoting bridge formation reconnecting neural tissue at lesion site. The mechanical properties of biomaterials are critical successful design ensure stable support as soon possible when compressed surrounding spine musculature. Poly(propylene fumarate) (PPF) scaffolds with high strength shown provide firm spatial...
A hot stable field-reversed configuration (FRC) has been produced in the C-2 experiment by colliding and merging two high-β plasmoids preformed dynamic version of θ-pinch technology. The process exhibits highest poloidal flux amplification obtained a magnetic confinement system (over tenfold increase). Most kinetic energy is converted into thermal with total temperature (T{i}+T{e}) exceeding 0.5 keV. final FRC state record lifetime approaching classical values. These findings should have...
Silicon nanoparticles were prepared by ultrafast laser ablation of a silicon target in deionized water. The characterized using optical absorption, Raman spectroscopy, and transmission electron microscopy. mean size is found to vary from 60 2.5 nm the absence any reducing chemical reagents, decreasing pulse energy value. High-resolution microscopy together with spectroscopy confirms crystalline structure generated nanoparticles. confinement carriers which evaluated experiments varies 90 550...
Heavy-metal-free semiconductor material like Silicon Nanoparticle (Si-NPs) is attracting scientists because of their diverse applications in biomedical field.In this work, pulsed laser ablation silicon aqueous solution employed to generate Si-NPs one step avoiding use chemical precursors.Characterization by absorption, electron and photoluminescence analysis proves the generation luminescent Si-NPs.The productivity rate investigated Inductively Coupled Plasma Spectrometry.Furthermore,...
An investigation on the productivity of silicon nanoparticles by picosecond laser ablation in water is presented. A systematic experimental study performed as function wavelength, fluence and time. In case at 1064 nm with a mean diameter 40 are produced. Instead, 355 results 9 for short time while decreases to 3 longer original model based in-situ ablation/photo-fragmentation physical process developed, it very well explains findings. The reported phenomenological has general validity, can...
A picosecond laser ablation approach has been developed for the synthesis of ligand-free AuAg bimetallic NPs where relative amount Ag is controlled in situ through a shielding effect. Various measurements, such as optical spectroscopy, transmission electron microscopy combined with energy dispersive X-ray spectroscopy and inductively coupled plasma emission spectrometry, revealed generation homogenous 15 nm average size different compositions tunable localized surface plasmon resonance....
Biofunctionalized silicon quantum dots were prepared through a one step strategy avoiding the use of chemical precursors. UV-Vis spectroscopy, Raman spectroscopy and HAADF-STEM prove oligonucleotide conjugation to surface nanoparticle with an average size 4 nm. The results from size-quenching effect during in situconjugation. Photoemissive properties, efficiency stability these pure colloids studied demonstrate bio-application potential, e.g. for nucleic acid vector delivery semiconducting,...
The Horizon 2020 Project EuPRAXIA ("European Plasma Research Accelerator with eXcellence In Applications") is preparing a conceptual design report of highly compact and cost-effective European facility multi-GeV electron beams using plasma as the acceleration medium. accelerator will be based on laser and/or beam driven approach used for photon science, high-energy physics (HEP) detector tests, other applications such X-ray sources medical imaging or material processing. started in November...
On the wake of results obtained so far at SPARC_LAB test-facility Laboratori Nazionali di Frascati (Italy), we are currently investigating possibility to design and build a new multi-disciplinary user-facility, equipped with soft X-ray Free Electron Laser (FEL) driven by ∼1 GeV high brightness linac based on plasma accelerator modules. This study is performed in synergy EuPRAXIA study. In this paper report about recent progresses going facility.
Abstract Radiotherapy with very high energy electrons has been investigated for a couple of decades as an effective approach to improve dose distribution compared conventional photon-based radiotherapy, the recent intriguing potential dose-rate irradiation. Its practical application treatment hindered by lack hospital-scale accelerators. High-gradient laser-plasma accelerators (LPA) have proposed possible platform, but no experiments so far explored feasibility clinical use this concept. We...
The diffraction limit in direct-laser-writing (DLW) lithography can be circumvented by selective inhibition of the polymerization. By combining nanosecond transient absorption spectroscopy and density functional theory it is demonstrated that polymerization possible a direct lowest triplet state. Polymerization state (TSA) has potential to bring DLW into nanometer scale. In field photopolymerization, multi-photon lithography1 stands out as mask-free tool for fabricating three-dimensional...
A straightforward fabrication technique to obtain patterned substrates promoting ordered neuron growth is presented. Chemical vapor deposition (CVD) single layer graphene (SLG) was machined by means of pulse UV laser ablation at the lowest effective fluence in order minimize damage effects. Patterned were then coated with poly-D-lysine a simple immersion solution. Primary embryonic hippocampal neurons cultured on our substrate, demonstrating an interconnected pattern mimicking design....
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A high temperature field reversed configuration (FRC) has been produced in the newly built, world’s largest compact toroid (CT) facility, C-2, by colliding and merging two high-β CTs using advanced field-reversed θ-pinch technology. This long-lived, stable merged state exhibits following key properties: (1) apparent increase poloidal flux from first pass to final state, (2) significantly improved confinement compared conventional FRCs with decay rates approaching classical values some cases,...
A novel approach for nanofabricating protein-functionalized luminescent silicon nanoparticles based on infrared ultrafast laser ablation of in an aqueous solution Staphylococcus aureus protein is reported. It demonstrated that 8 nm A-capped quantum dots with blue-green photoemissive properties are generated. The conjugation efficiency studies reveal a high percentage attached to the Si nanoparticle surface through physical adsorption phenomena during situ process. biological functionality...
A novel electrowetting-on-dielectrics (EWOD) device in open planar geometry allows probing of droplet mixing on a superhydrophobic substrate under quasi contact-free conditions. We demonstrate droplet-based microreactor with integrated convective-flow for the reactive-mixing CaCl2/Na2CO3 solutions. The provides unique conditions scattering, spectroscopy and imaging probes requiring an unobstructed droplet-access.
Selective inhibition of the polymerization leads to sub-diffraction feature sizes in direct writing lithography—a principle based on idea stimulated emission depletion (STED) microscopy. However, detailed understanding process is a key point further enhance resolution system. The authors present experiments focused time dynamics process, clarifying possible photophysical pathways. significance laser (DLW) lithography increased considerably during last years.1–3 ability arbitrary structures...
High-resolution spectroscopy of xenon is performed on four transitions from the ${5p}^{6}{}^{1}{S}_{0}$ ground state to ${5d}^{\ensuremath{'}}[3/2{]}_{1},$ $8d[1/2{]}_{1},$ $8d[3/2{]}_{1},$ and ${7s}^{\ensuremath{'}}[1/2{]}_{1}$ excited states $(jl$-coupling notation) by means $1\mathrm{VUV}+1\mathrm{UV}$ photoionization spectroscopy. Spectra all nine stable isotopes are resolved enabling determination hyperfine splittings isotope shifts. Magnetic dipole (for both ${}^{129}\mathrm{Xe}$...
Ultra small silicon nanoparticles (Si-NPs) with narrow size distribution are prepared in a one step process by UV picosecond laser ablation of bulk liquid. Characterization electron microscopy and absorption spectroscopy proves Si-NPs generation an average 2 nm resulting from situ photofragmentation effect. In this context, the current work aims to explore liquid medium (water toluene) effect on structure optical properties colloidal solution. high pressure (s.g. Fm3m) diamond-like Fd3m),...
Abstract The interaction of ultraintense laser pulses with solids is largely affected by the plasma gradient at vacuum–solid interface, which modifies absorption and ultimately, controls energy distribution function heated electrons. A micrometer scale-length has been predicted to yield a significant enhancement weight fast electron population play major role in laser-driven proton acceleration thin foils. We report on recent experimental results from foil targets ultra-relativistic...
We describe the principle and status of PVLAS experiment which is being assembled at INFN Laboratori Nazionali di Legnaro (Legnaro, Padua, Italy) to look for coherent effects, related QED vacuum structure, on propagation a polarized light beam in strong magnetic field.
The effect of the spot diameter in nanosecond excimer laser percussion drilling through via silicon wafer is presented. Experimental results show a ten fold increase ablation efficiency when decreasing from 220 μm to 9 at constant fluence range 7.5 J/cm(2) 13.2 J/cm(2). Such absent using 60 ps deep-UV pulses. A model developed that explain findings terms plume shielding on pulse. successfully applied also previously published data Polyamide and Alumina.