A5053651553- Multiple Sclerosis Research Studies
- Glioma Diagnosis and Treatment
- Hearing Loss and Rehabilitation
- Epilepsy research and treatment
- Brain Metastases and Treatment
- Peripheral Neuropathies and Disorders
- Functional Brain Connectivity Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Salivary Gland Disorders and Functions
- Herpesvirus Infections and Treatments
- Meningioma and schwannoma management
- Polyomavirus and related diseases
- Vascular Malformations Diagnosis and Treatment
- Pharmacological Effects and Toxicity Studies
- Hearing, Cochlea, Tinnitus, Genetics
- Neurofibromatosis and Schwannoma Cases
- Neural dynamics and brain function
- Blood Pressure and Hypertension Studies
- Neuroscience and Music Perception
- Monoclonal and Polyclonal Antibodies Research
- Otitis Media and Relapsing Polychondritis
- Fungal Plant Pathogen Control
- Neurogenesis and neuroplasticity mechanisms
- Vasculitis and related conditions
- Nerve injury and regeneration
Universidad Cardenal Herrera CEU
2024
Hospital General Universitari de Castelló
2010-2023
Fundación Hospital Provincial de Castellón
2014
Complejo Hospitalario de Navarra
2013
Institut Català d'Oncologia
2013
Hospital Clínico San Carlos
2013
Complejo Hospitalario Universitario de Santiago
2013
Hospital Universitario Miguel Servet
2013
The aims of this study were to determine which cognitive domains are evaluated by the Paced Auditory Serial Addition Test (PASAT) and identify them responsible for poorer performance displayed multiple sclerosis (MS) patients in task. A total 30 healthy controls MS completed PASAT task as well different tests contained Brief Repeatable Battery Neuropsychological Tests (BRB-N), some Wechsler Adult Intelligence Scale (WAIS-III) subtests, Spanish version Chicago Multiscale Depression Inventory...
To assess management patterns and outcome in patients with glioblastoma multiforme (GBM) treated during 2008–2010 Spain. Retrospective analysis of clinical, therapeutic, survival data collected through filled questionnaires from histologically confirmed GBM diagnosed 19 Spanish hospitals. We identified 834 (23% aged >70 years). Surgical resection was achieved 66% patients, although the extent surgery by postoperative MRI only 41%. There were major complications 14% age independent predictor...
Fatigue is one of the most frequent symptoms in multiple sclerosis (MS), and recent studies have described a relationship between sensorimotor cortex its afferent efferent pathways as substrate fatigue. The objectives this study were to assess neural correlates fatigue MS through gray matter (GM) white (WM) atrophy, resting state functional connectivity (rs-FC) network (SMN). Eighteen healthy controls (HCs) 60 relapsing-remitting patients assessed with Severity Scale (FSS). Patients...
Objective: The objective of this paper is to explore differences in resting-state functional connectivity between cognitively impaired and preserved multiple sclerosis (MS) patients. Methods: Sixty MS patients 18 controls were assessed with the Brief Repeatable Battery Neuropsychological Tests (BRB-N). A global Z score BRB-N was obtained allowed us classify as ( n = 30 per group). Functional by independent component analysis networks (RSNs) related cognition: default mode network, left right...
The objective in this paper is to compare the cumulative incidence and density of therapy-related acute myeloid leukaemia two cohorts patients with multiple sclerosis treated mitoxantrone, previously reported data literature. Six new cases were observed by prospectively following Spanish series 142 88 worsening relapsing secondary-progressive disease mitoxantrone. A literature review shows 32 further reported, 65.6% which are promyelocytic leukaemia. Five fulfilled diagnostic criteria for...
The Paced Auditory Serial Addition Test (PASAT) and the Symbol Digit Modalities (SDMT) are generally used to detect cognitive impairments in multiple sclerosis patients. Although both seem be sensitive slow information-processing speed, some results suggest that they do not involve same functions. aim of present study is observe possible differences between these tasks help understand their utility assessment. A total 17 participants were recruited for completed a block-design version each...
Background: Previous studies have suggested a relationship between neuroanatomical and neurofunctional hippocampal alterations episodic memory impairments in multiple sclerosis (MS) patients. Objective: We examined hippocampus volume functional connectivity (FC) changes MS patients with different capabilities. Methods: Hippocampal subfield FC were compared two subgroups of without impairment (multiple impaired (MSi) preserved (MSp), respectively) healthy controls (HC). A discriminant...
The present observational, multicenter, retrospective study investigated the efficacy and tolerability of lacosamide in controlling secondary epileptic seizures patients with brain tumors Spain. Data from medical records ≥18 years age tumors, who had received at least one dose for seizure management between July 2013 November 2013, were collected. primary objectives to assess effectiveness lacosamide. 39 (mean age, 54.1 years; 66.7% male) collected, where two main reasons initiation...
Abstract The Paced Auditory Serial Addition test (PASAT) is a sensitive task for evaluating cognitive impairment in patients with diffuse brain disorders, such as multiple sclerosis patients. Brain areas involved this have been investigated diverse fMRI studies using different methodologies to control the subjects' responses during scanning. Here, we examined possible differences between overt and covert PASAT 13 volunteers. Results showed similar activations parietal frontal both versions...
Overview: We assessed the role of age and disease activity as new factors contributing to establish risk progressive multifocal leucoencephalopathy in multiple sclerosis patients treated with natalizumab 36 University Hospitals Europe. performed study 1,307 (70.8% anti-John Cunninghan virus positive antibodies) for a median time 3.28 years. Epidemiological, clinical, laboratory variables were collected. Lipid-specific IgM oligoclonal band status was available 277 patients. Factors associated...
<b><i>Background:</i></b> Reduced information-processing speed (IPS) is a primary cognitive deficit of multiple sclerosis (MS) patients. The neural efficiency hypothesis describes an inverse relationship between performance in task and the amount resources devoted to it. Previous studies have shown that provides appropriate framework explore dysfunction neurological <b><i>Objective:</i></b> aim this study was regarding IPS capabilities...
One of the most prevalent cognitive deficits in multiple sclerosis (MS) patients relates to (both verbal and visual) information encoding, a process related hippocampus.To assess relationship between learning long-term retention processes hippocampal volume functional connectivity (FC) MS patients.MS control group healthy volunteers were assessed using brief neuro-psychological battery, which includes tests visual memory. Gray matter was through voxel based morphometry technique, study...
Introduction: We have different treatment alternatives for relapsing-remitting multiple sclerosis-RRMS-within the so-called platform drugs. It would be desirable to know ideal drug each patient. Real clinical practice studies provide us with data on efficacy in medium and long term, safety beyond trials, can help patient profile appropriate therapy. Material Methods: An observational multicenter study of real patients RRMS who were treated teriflunomide Valencian Community, since was...
Endovenous thrombolysis is the preferred treatment in early hours following cerebral infarction and delays are main obstacle preventing it from being used on a more widespread basis. The stroke code (SC) system that allows patients to be identified quickly taken most suitable hospital for such implemented. AIM. To determine impact of extending intra-hospital SC (ISC) provincial (PSC).The consists prospective register cases treated centre. Data admitted consecutively year prior after...
Meningoencephalomyelitis can be due to a number of treatable causes. A tumoural aetiology is rare and they are generally malignant tumours with an ominous prognosis. We report case meningoencephalomyelitis that initially presented as encephalitis herpes simplex virus (HSV) which was finally seen anaplastic oligoastrocytoma.We describe the 68-year-old male history just strong low back pain during previous month, who admitted hospital because progressive clinical symptoms involving cognitive...