Hanchih Wu

ORCID: 0000-0003-2769-6653
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About
Contact & Profiles
Research Areas
  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Oral health in cancer treatment
  • Animal Nutrition and Physiology
  • Meat and Animal Product Quality
  • Inflammatory Bowel Disease
  • Asthma and respiratory diseases
  • Immunotherapy and Immune Responses
  • Autoimmune and Inflammatory Disorders
  • Head and Neck Cancer Studies
  • Biochemical Analysis and Sensing Techniques
  • Microscopic Colitis
  • Eosinophilic Esophagitis
  • Oral Health Pathology and Treatment
  • Diabetes and associated disorders
  • IL-33, ST2, and ILC Pathways

Icahn School of Medicine at Mount Sinai
2016-2025

Sixth Affiliated Hospital of Sun Yat-sen University
2024

Sun Yat-sen University
2024

Academia Sinica
2016

Jiangxi Agricultural University
2009

Transcription factor Tox2 plays a key role to maintain T FH phenotype and generate memory cells in both mice humans.

10.1126/sciadv.abj1249 article EN cc-by-nc Science Advances 2021-10-08

Two experiments were carried out to investigate the effects of Lactobacillus culture (LC) on growth performance and color meat skin broiler chickens. A total 362 one-day-old Arbor Acres broilers allocated 7 treatments, with strains LC in experiment 1. The results showed significant differences shank starter among dietary supplements different LC. effect xanthophyll deposition birds was evaluated 1 strain MA (Lactobacillus salivarius) 2. 208 male chicks randomly into 4 treatments replicates...

10.3382/japr.2009-00012 article EN cc-by-nc-nd The Journal of Applied Poultry Research 2009-09-15

Assessment of the quality and breadth antigen (Ag)-specific memory T cells in human samples is paramount importance to elucidate pathogenesis develop new treatments various diseases. T-cell receptor (TCR) signal strength, primarily controlled by TCR affinity, affects many fundamental aspects biology; however, no current assays for detection Ag-specific CD8+ can assess their strength samples. Here, we provide evidence that interferon regulatory factor 4 (IRF4), a transcription rapidly...

10.1182/bloodadvances.2019000292 article EN cc-by-nc-nd Blood Advances 2019-07-18

Ustekinumab (UST) is recommended as the first-line treatment for patients with moderate to severe Crohn's disease (CD). However, efficacy of certain may be suboptimal and necessitate intensive or modification regimen. We sought establish a nomogram model predict short-term effectiveness UST in CD patients. established derivation cohort comprising diagnosed treated at Sixth Affiliated Hospital Sun Yat-sen University from May 2020 July 2023. The patient data, including demographic clinical...

10.2147/jir.s479618 article EN cc-by-nc Journal of Inflammation Research 2024-11-01

Abstract Asthma is a major public health problem that affects nearly 10% of the general population and thought to be mediated by allergen-specific Th2 cells, adaptive immunity allergic inflammation. Current treatments for asthma generally focus on minimizing Th2-driven eosinophilic inflammation with use anti-inflammatory therapies such as corticosteroids. However, this approach, targeting cell corticosteroids, has not reduced high rates hospitalizations acute asthma, most often caused viral...

10.4049/jimmunol.196.supp.53.1 article EN The Journal of Immunology 2016-05-01
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