- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Oral health in cancer treatment
- Animal Nutrition and Physiology
- Meat and Animal Product Quality
- Inflammatory Bowel Disease
- Asthma and respiratory diseases
- Immunotherapy and Immune Responses
- Autoimmune and Inflammatory Disorders
- Head and Neck Cancer Studies
- Biochemical Analysis and Sensing Techniques
- Microscopic Colitis
- Eosinophilic Esophagitis
- Oral Health Pathology and Treatment
- Diabetes and associated disorders
- IL-33, ST2, and ILC Pathways
Icahn School of Medicine at Mount Sinai
2016-2025
Sixth Affiliated Hospital of Sun Yat-sen University
2024
Sun Yat-sen University
2024
Academia Sinica
2016
Jiangxi Agricultural University
2009
Transcription factor Tox2 plays a key role to maintain T FH phenotype and generate memory cells in both mice humans.
Two experiments were carried out to investigate the effects of Lactobacillus culture (LC) on growth performance and color meat skin broiler chickens. A total 362 one-day-old Arbor Acres broilers allocated 7 treatments, with strains LC in experiment 1. The results showed significant differences shank starter among dietary supplements different LC. effect xanthophyll deposition birds was evaluated 1 strain MA (Lactobacillus salivarius) 2. 208 male chicks randomly into 4 treatments replicates...
Assessment of the quality and breadth antigen (Ag)-specific memory T cells in human samples is paramount importance to elucidate pathogenesis develop new treatments various diseases. T-cell receptor (TCR) signal strength, primarily controlled by TCR affinity, affects many fundamental aspects biology; however, no current assays for detection Ag-specific CD8+ can assess their strength samples. Here, we provide evidence that interferon regulatory factor 4 (IRF4), a transcription rapidly...
Ustekinumab (UST) is recommended as the first-line treatment for patients with moderate to severe Crohn's disease (CD). However, efficacy of certain may be suboptimal and necessitate intensive or modification regimen. We sought establish a nomogram model predict short-term effectiveness UST in CD patients. established derivation cohort comprising diagnosed treated at Sixth Affiliated Hospital Sun Yat-sen University from May 2020 July 2023. The patient data, including demographic clinical...
Abstract Asthma is a major public health problem that affects nearly 10% of the general population and thought to be mediated by allergen-specific Th2 cells, adaptive immunity allergic inflammation. Current treatments for asthma generally focus on minimizing Th2-driven eosinophilic inflammation with use anti-inflammatory therapies such as corticosteroids. However, this approach, targeting cell corticosteroids, has not reduced high rates hospitalizations acute asthma, most often caused viral...