A5079022937- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Sarcoidosis and Beryllium Toxicity Research
- Radiation Dose and Imaging
- Ultrasound in Clinical Applications
- Radiology practices and education
- Innovations in Medical Education
- Lung Cancer Diagnosis and Treatment
- Systemic Sclerosis and Related Diseases
- Venous Thromboembolism Diagnosis and Management
- Pneumothorax, Barotrauma, Emphysema
- Occupational and environmental lung diseases
- Inflammatory Myopathies and Dermatomyositis
- Medical Imaging and Pathology Studies
- Histiocytic Disorders and Treatments
- Occupational exposure and asthma
- Vasculitis and related conditions
- Advanced X-ray and CT Imaging
- Immunodeficiency and Autoimmune Disorders
- Trauma Management and Diagnosis
- Cardiac Imaging and Diagnostics
- Eosinophilic Disorders and Syndromes
- Cardiac Arrest and Resuscitation
- Medical Imaging Techniques and Applications
- Abdominal Trauma and Injuries
- Infectious Diseases and Tuberculosis
Creighton University
2023-2024
Mayo Clinic in Arizona
2016-2022
Mayo Clinic
2015-2022
WinnMed
2020
Pulmonary and Critical Care Associates
2018
University of Milano-Bicocca
2017
National Jewish Health
2012-2014
Rocky Vista University
2014
University of Colorado Denver
2012-2014
University of Southern California
2014
Abstract Langerhans cell histiocytosis (LCH) can affect children and adults with a wide variety of clinical manifestations, including unifocal, single-system multifocal, pulmonary (smoking-associated), or multisystem disease. The existing paradigms in the management LCH are mostly derived from pediatric literature. Over last decade, discovery clonality MAPK-ERK pathway mutations most cases led to recognition as hematopoietic neoplasm, opening doors for treatment targeted therapies. These...
The authors administered CAT scans and neuropsychological tests to 16 adolescents with obsessive-compulsive disorder (mean age +/- SD = 13.7 1.6 years) matched controls. patients had a mean ventricular-brain ratio (VBR) significantly higher than the controls' showed spatial-perceptual deficits similar those found in frontal lobe lesions. Memory, reaction time, decision time did not differ from controls'. Neurodevelopmental examination of seven yielded high frequency age-inappropriate...
CT Features of the Usual Interstitial Pneumonia Pattern: Differentiating Connective Tissue Disease–Associated Lung Disease From Idiopathic Pulmonary FibrosisJonathan H. Chung1, Christian W. Cox2, Steven M. Montner2, Ayodeji Adegunsoye3, Justin Oldham3, Aliya N. Husain4, Rekha Vij3, Imre Noth3, David A. Lynch5 and Mary E. Strek3Audio Available | Share Claim CREDIT
Ultrasound (US) is an extremely useful diagnostic imaging modality because of its real-time capability, noninvasiveness, portability, and relatively low cost. It carries none the potential risks ionizing radiation exposure or intravenous contrast administration. For these reasons, numerous medical specialties now rely on US not only for diagnosis guidance procedures, but also as extension physical examination. In addition, many school educators recognize usefulness this technique aid to...
The aim of this study was to evaluate the clinical impact a higher spatial resolution, full field-of-view investigational photon-counting detector computed tomography (PCD-CT) on radiologist confidence in imaging findings and diagnosis usual interstitial pneumonia (UIP) compared with conventional energy-integrating CT (EID-CT).Patients suspected lung disease were scanned PCD-CT system after informed consent clinically indicated EID-CT. In 2 sessions, 3 thoracic radiologists blinded history...
Granulomatous-lymphocytic interstitial lung disease (GLILD) has emerged as a major cause of morbidity in patients with common variable immunodeficiency (CVID). While GLILD is among the most serious noninfectious pulmonary complications CVID, risk factors for this condition have not been reported.To identify clinical, physiologic, and serologic adults CVID.Of 345 consecutive adult we identified 34 National Jewish Health research database who had radiographic-pathologic diagnosis evaluated...
Mycobacterium abscessus group lung infection is characterized by low cure rates. Improvement in quality of life may be a reasonable treatment goal.The objective this study was to evaluate change response therapy, predictors improvement life, and association with traditional outcome measures.Forty-seven patients were treated for (including one chelonae) followed prospectively 2 years between December 2009 May 2012. St. George's Respiratory Questionnaire (SGRQ) administered, chest computed...
Rationale: The demographic, physiological, and computed tomography (CT) features associated with pneumothorax in smokers without chronic obstructive pulmonary disease (COPD) are not clearly defined.Objectives: We evaluated the hypothesis that is male sex, tall thin stature, airflow obstruction, increased total subpleural emphysema.Methods: study included COPD from COPDGene Study, quantitative chest CT analysis. Pleural-based emphysema was assessed on basis of local histogram measures...
Purpose: Differentiating between systemic sclerosis-related interstitial lung disease (SSc-ILD) and idiopathic pulmonary fibrosis (IPF) is important because of the differences in workup, prognosis, treatment. However, there much overlap appearance these 2 entities on high-resolution computed tomography. We propose that inflammation and/or focally or disproportionately involving bilateral anterolateral upper lobes posterosuperior lower [“Four Corners” Sign (FCS)] specific for SSc-ILD....
Langerhans cell histiocytosis (LCH) is a histiocytic neoplasm that can involve the lungs as single system (LCH-SSL) or multisystem disease (LCH-MSL). The role of full-body radiographic staging to determine whether patients have LCH-SSL LCH-MSL unclear. Long-term outcomes versus and without lung involvement (LCH-MSNL) are unknown. A retrospective study adult LCH seen at our center from January 2000 2020 was performed. In Part 1, we addressed utility whole-body imaging among those presenting...
Purpose: The purpose of this study was to describe a characteristic magnetic resonance imaging (MRI) appearance lymphadenopathy in sarcoidosis—the dark lymph node sign (DLNS)—and determine its prevalence retrospective review cardiopulmonary MRI examinations obtained patients with sarcoidosis. Materials and Methods: Fifty-one adult clinical history sarcoidosis were evaluated thoracic during 15-month span; 29 men, 22 women. average age 53.7±11.2 years. Patients considered have the DLNS on if...
Background The association between interstitial lung disease (ILD) and myeloperoxidase (MPO)-antineutrophil cytoplasmic antibodies (ANCAs) has been described, but pathologic characteristics are not well characterized. Objectives We assessed the radiologic of ILD in MPO-ANCA-positive patients vasculitis, particularly microscopic polyangiitis (MPA). Methods retrospectively searched electronic health records to identify with who underwent surgical biopsy at our institution from January 1997...
Background Spontaneous pneumomediastinum (SP) is an uncommon disorder but has been described in cases with connective tissue diseases (CTDs), most commonly dermatomyositis and polymyositis. We aimed to explore this relationship by analyzing the characteristics of CTD patients SP. Methods Using a computer-assisted search, we identified 25 SP evaluated between January 1997 December 2016 at our institution. Clinicoradiologic characteristics, treatment, outcomes were extracted chest computed...
Percutaneous vertebroplasty (PV) is a procedure commonly used for the treatment of vertebral compression fractures, and number procedures has been steadily increasing over past decade. We report case an 81 year old female with history breast cancer that developed two body fractures was subsequently treated PV. The patient subsegmental pulmonary polymethylmethacrylate (PMMA) embolus as complication procedure. Ten years following procedure, she remained asymptomatic PMMA being discovered...
To identify a predictive value for the exacerbation status of chronic obstructive pulmonary disease (COPD) subjects, we evaluated relationship between vascular measurements on chest CT and severe COPD exacerbation. Six hundred three subjects enrolled in COPDGene population were included divided into nonexacerbator (n = 313) exacerbator 290) groups, based whether they had an emergency room visit and/or hospitalization We measured diameter main artery (MPA) ascending aorta (AA) at 2 different...
To describe the pulmonary imaging findings in patients with Cowden syndrome (CS).A retrospective review identified all CS who underwent dedicated computed tomography examinations of chest at our institution between January 2000 and October 2017. Patient demographics characteristics were through a electronic medical record relevant imaging.Fifteen (6 males/9 females; mean age 53 y) clinical diagnosis identified. Genetic confirmation PTEN mutation was available 8/15 (50%) patients. Pulmonary...