A5100337091- Acute Myocardial Infarction Research
- Food Allergy and Anaphylaxis Research
- Venous Thromboembolism Diagnosis and Management
- Hereditary Neurological Disorders
- Allergic Rhinitis and Sensitization
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Antiplatelet Therapy and Cardiovascular Diseases
- Respiratory viral infections research
- Cardiovascular Function and Risk Factors
- Cancer, Stress, Anesthesia, and Immune Response
- Whipple's Disease and Interleukins
- Inflammatory Biomarkers in Disease Prognosis
- GDF15 and Related Biomarkers
- Sepsis Diagnosis and Treatment
- Diabetes Treatment and Management
- Viral Infections and Immunology Research
- Vascular Tumors and Angiosarcomas
- Garlic and Onion Studies
- Biosensors and Analytical Detection
- Cardiac Imaging and Diagnostics
- Erythropoietin and Anemia Treatment
- Diabetic Foot Ulcer Assessment and Management
- Peroxisome Proliferator-Activated Receptors
- Lipoproteins and Cardiovascular Health
- Viral gastroenteritis research and epidemiology
Capital Medical University
2014-2025
Beijing Tian Tan Hospital
2025
General Hospital of Shenyang Military Region
2015-2024
Shanghai Jiao Tong University
2013-2022
Radiation Oncology Associates
2022
China-Japan Friendship Hospital
2007-2021
Chengdu Women's and Children's Central Hospital
2020
Mayo Clinic
2015
National Institute for Viral Disease Control and Prevention
2014
The safety and efficacy of bivalirudin compared with heparin or without glycoprotein IIb/IIIa inhibitors in patients acute myocardial infarction (AMI) undergoing primary percutaneous coronary intervention (PCI) are uncertain.To determine if is superior to alone plus tirofiban during PCI.Multicenter, open-label trial involving 2194 AMI PCI at 82 centers China between August 2012 June 2013.Patients were randomly assigned receive a post-PCI infusion (n = 735), 729), 730). Among treated...
Abstract Background Allergy involves a series of complex reactions and factors that contribute to the development disease triggering symptoms, including rhinitis, asthma, atopic eczema, skin sensitivity, even acute fatal anaphylactic shock. Prediction evaluation potential allergenicity is importance for safety foods other environment factors. Although several computational approaches assessing proteins have been developed, their performance relative merits shortcomings not compared...
Abstract Epidemiological studies suggested complicated associations between type 2 diabetes mellitus and breast cancer. There is a significant inverse association high‐density lipoprotein (HDL) the risk mortality of However, HDL could be modified in various ways patients, this may lead to altered effects on many different types cells. In our study, we found that glycation oxidation levels are significantly higher from patients compared healthy subjects. Diabetic dramatically had stronger...
Casein and α-lactalbumin (α-LA) are the main allergens in cow's milk, which can affect skin, respiratory system, gastrointestinal tract, even cause anaphylactic shock. Developing a rapid sensitive detection method of casein α-LA is still pursued. Herein, surface-enhanced Raman scattering based lateral flow assay (SERS-LFA) for highly milk food was established effectively preventing allergic symptoms. [email protected] nanoparticles ([email NPs) were synthesized as SERS active substrate to...
Spontaneous reperfusion (SR) and early infarct related artery (IRA) patency before primary percutaneous coronary intervention (PPCI) might bring extra benefit for patients with ST-segment elevation myocardial infarction (STEMI). This study premilinarily screened the independent predictors of SR, assessed relationship between SR plasma homocysteine (HCY). The medical records 998 who were diagnosed as STEMI underwent emergency angiography retrospectively studied, was defined achievement TIMI...
We evaluated a cohort of patients with cardiac angiosarcomas (CA) who developed brain metastases (BM) to define outcomes and intracranial hemorrhage (IH) risk.We reviewed 26 consecutive BM treated between 1988 2020 identified from departmental CA (n=103) database. Causes death were recorded, terminal (TH) was defined as an IH that caused or prompted transfer hospice.The prevalence 25% (n=26/103). A total 23 (88%) had IH, including 21 (81%) at initial diagnosis, which 18 (86%) required...
Objectives: To explore the efficiency and safety of bivalirudin in patients undergoing emergency percutaneous coronary intervention via radial access. Background: Bivalirudin reduces bleeding risks over heparin PCI. However, advantages transradial is uncertain. Methods: In BRIGHT trial, 1,723 underwent PCI access, with 576 arm, arm 571 plus tirofiban arm. The primary outcome was 30‐day net adverse clinical event (NACE), defined as a composite major cardiac cerebral events or any bleeding....
Abstract Background Charcot–Marie–Tooth (CMT) disease is an exciting field of study, with a growing number causal genes and expanding phenotypic spectrum. The microrchidia family CW-type zinc finger 2 gene (MORC2) was newly identified as causative CMT2Z in 2016. We aimed to describe the phenotypic-genetic spectrum MORC2-related diseases Chinese population. Methods With use Sanger sequencing Next Generation Sequencing (NGS) technologies, we screened cohort 284 unrelated CMT2 families....
Background After being polio free for more than 10 years, an outbreak following importation of wild poliovirus (WPV) was confirmed in Xinjiang Uygur Autonomous Region, China, 2011. Methods A cross-sectional study conducted prior to supplementary immunization activities (SIAs), immediately after the confirmation WPV outbreak. In selected prefectures, participants aged ≤60 years old who visited hospitals at county-level or above have their blood drawn reasons not related study, were invited...
ABSTRACT Background The objective of this study was to investigate cardiovascular disease risk factor ( cvRF ) profiles and compare their trends over 17 years in patients with without acute coronary syndrome ACS undergoing percutaneous intervention PCI ). Hypothesis Time are different between non‐ACS patients. Methods This a time‐trend analysis from 1994 2010 within the Mayo Clinic registry. Outcome measures were incidence prevalence , including Framingham Risk Score FRS ), at time admission...
Abstract Objective: Ticagrelor on Health Outcomes in diabEtes Mellitus patients Intervention Study (THEMIS) filled an important data gap by showing a significant reduction of ischemic cardiovascular events ticagrelor plus aspirin cohort compared with placebo among coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM) but without history myocardial infarction. This study aims to evaluate the applicability THEMIS results real-world clinical setting China. Methods: retrospective,...
Background: Open oral food challenge (OFC) is a useful tool in management of non-IgE mediated cow's milk allergy (CMPA) infants. Because COVID-19 pandemic, clinical services for noninfectious diseases were hard to maintain as usual. Internet hospital model medicine got more profoundly involved the medical service systems. Methods:we used hospital-led mobile application (APP) platform guide open OFC conducted at home, and assessed effect this novel by comparing with traditional pattern OFCs....
We aimed to study level of cardiac troponin T(cTnT) and its possible influence factorsin maintenance hemodialysis (MHD) patients. Blood was obtained from 123 MHD patients before undergoing hemodialysis. Patients with cardiovascular disease (CVD) had higher cTnT levels than those without CVD (0.062 [0.044 - 0.083] ng/mL vs 0.031[0.020 0.046] ng/mL, P = 0.002). diabetes mellitus (DM) non-DM (0.061[0.042 0.102] 0.044[0.025 0.064] 0.003). found that in all patients, correlated positively age(ρ...
Abstract Objective Charcot –Marie–Tooth (CMT) disease is an exciting field of study, with a growing number causal genes and expanding phenotypic spectrum. The microrchidia family CW-type zinc finger 2 gene (MORC2) was newly identified as causative CMT2Z in 2016. We aimed to describe the phenotypic-genetic spectrum MORC2-related diseases Chinese population. Methods With use Sanger sequencing Next Generation Sequencing (NGS) technologies, we screened cohort 284 unrelated CMT2 families....