A5100357077- Nanopore and Nanochannel Transport Studies
- Membrane Separation Technologies
- Graphene research and applications
- Catalysis for Biomass Conversion
- Nanoparticle-Based Drug Delivery
- Carbon dioxide utilization in catalysis
- Antimicrobial Peptides and Activities
- Catalysts for Methane Reforming
- Polymer Surface Interaction Studies
- Advanced Memory and Neural Computing
- Graphene and Nanomaterials Applications
- Advanced Drug Delivery Systems
- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- Blood Coagulation and Thrombosis Mechanisms
- Blood properties and coagulation
- Antibiotic Resistance in Bacteria
- Hydrogels: synthesis, properties, applications
- Computational Drug Discovery Methods
- Adipose Tissue and Metabolism
- Biopolymer Synthesis and Applications
- Mitochondrial Function and Pathology
- Inhalation and Respiratory Drug Delivery
- Advancements in Transdermal Drug Delivery
- Agricultural risk and resilience
Tianjin University
2025
Nanjing Agricultural University
2025
Hebei Medical University
2025
Hebei University
2025
Institute of Physics
2025
Beijing Chao-Yang Hospital
2024
Capital Medical University
2024
Zhejiang University
2019-2024
University of California, Berkeley
2024
Lawrence Berkeley National Laboratory
2024
The successful implementation of thin-film composite membranes (TFCM) for challenging solute-solute separations in the pharmaceutical industry requires a fine control over microstructure (size, distribution, and connectivity free-volume elements) thickness selective layer. For example, desalinating antibiotic streams highly interconnected elements right size to block antibiotics but allow passage salt ions water. Here, we introduce stevioside, plant-derived contorted glycoside, as promising...
Rapid biomimetic intrafibrillar mineralization of collagen was induced by polyelectrolyte–calcium complexes as a pre-precursor.
Abstract Dentin hypersensitivity (DH) is triggered by external stimuli irking fluid flow through exposed dentinal tubules (DTs). Three commercially available desensitizing agents as control in this study only achieve limited occlusion depths of ≈10 µm the DTs well scarce remineralization demineralized dentin matrix. Herein, polyelectrolyte‐calcium complexes pre‐precursor (PCCP) process proposed for managing DH that with rubbed ultrahighly concentrated suspension (4 g L −1 ‐5.44 m ) followed...
This study aims to analyze the influence of weather index insurance on farmers' credit default rates loan group in trust games. A field economic experiment was conducted with 324 farmers Heilongjiang Province, China. The results indicate that reduces and improves efficiency after mitigating natural risk. Trust between is an important factor affecting their rates. acts as a mediating variable, reinforcing effect In order reduce defaults by risks for financial institutions, government should...
Fatty acid (FA) biosynthesis is a crucial cellular process that converts nutrients into metabolic intermediates necessary for membrane biosynthesis, energy storage, and the production of signaling molecules. Acetyl-CoA carboxylase (ACACA) plays pivotal catalytic role in both fatty synthesis oxidation. This cytosolic enzyme catalyzes carboxylation acetyl-CoA to malonyl-CoA, which represents first rate-limiting step de novo biosynthesis. In this study, we developed rapid effective purification...
The emerging and global spread of a novel plasmid-mediated colistin resistance gene, mcr-1 , threatens human health. Expression the MCR-1 protein affects bacterial fitness this cost correlates with lipid A perturbation. However, exact molecular mechanism remains unclear. Here, we identified M6 variant carrying two-point mutations that conferred co-resistance to β-lactam antibiotics. Compared wild-type (WT) MCR-1, caused severe disturbance in A, resulting up-regulation L, D-transpeptidases...
Development of energy-efficient and low-cost desalination techniques is pivotal importance, reverse osmosis (RO) regarded as one the most promising solutions to tackle world water crisis has been widely deployed for large-scale distributed desalination. Graphene with nanopores was considered a membrane due its unique properties. However, intrinsic complexity process, together various tunable properties membranes/nanopores themselves, makes accurate prediction performance or designing new...
Abstract Human multidrug resistance protein 5 (hMRP5) effluxes anticancer and antivirus drugs, driving resistance. To uncover the mechanism of hMRP5, we determine six distinct cryo-EM structures, revealing an autoinhibitory N-terminal peptide that must dissociate to permit subsequent substrate recruitment. Guided by these molecular insights, design inhibitory could block entry into transport pathway. We also identify a regulatory motif, comprising positively charged cluster hydrophobic...
Abstract For first-order phase transitions, the second derivatives of Gibbs free energy (specific heat and compressibility) diverge at transition point, resulting in an effect known as super-elasticity along pressure axis, or super-thermicity temperature axis. Here we report a chemical analogy these singularity effects atomic doping where derivative (chemical susceptibility) diverges leading to anomalously high barrier for dopant diffusion co-existing phases, coin super-susceptibility. The...
Methanol synthesized from carbonate hydrogenation is of great importance for CO2 utilization indirectly. Herein, a series Cu/Zn/Al heterogeneous catalysts were prepared by co-precipitation with synchronous aging step, and applied diethyl (DEC) to produce methanol. Furthermore, the characterized physicochemical methods, such as N2 adsorption, ICP-OES, N2O titration, SEM, TEM, XRD, H2-TPR XPS in detail. Higher copper concentration led higher ratio bulk CuOx species calcined samples, which...
The synthesis of sustainable methanol and ethylene glycol (EG) via hydrogenation carbonate (EC) has caught researchers' growing interests on account the indirect chemical utilization CO2. Core-shell Cu@GO catalysts with random nanoporous network graphite oxide (GO) were synthesized a simple method ultrasonic precipitation. analyzed systematically by N2 physisorption, TGA measurement, XRD, FT-IR, Raman, TEM, SEM, XPS (XAES). In particular, mentioned was confirmed to be effective fabricate...