A5017133320- Heart Failure Treatment and Management
- SARS-CoV-2 and COVID-19 Research
- Health Systems, Economic Evaluations, Quality of Life
- Vaccine Coverage and Hesitancy
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- COVID-19 epidemiological studies
- Behavioral Health and Interventions
- Workplace Health and Well-being
- Diabetes Treatment and Management
- AI in Service Interactions
- Intramuscular injections and effects
- Digital Mental Health Interventions
- Cardiac Health and Mental Health
- Cardiovascular Issues in Pregnancy
- Heparin-Induced Thrombocytopenia and Thrombosis
- SARS-CoV-2 detection and testing
- Platelet Disorders and Treatments
- COVID-19 Clinical Research Studies
Ministry of Health
2022-2024
Queen Elizabeth Hospital
2023
Background Data comparing outcomes in heart failure ( HF ) across Asia are limited. We examined regional variation mortality among patients with enrolled the ASIAN ‐HF (Asian Sudden Cardiac Death Heart Failure) registry separate analyses for those reduced ejection fraction EF ; <40%) versus preserved (≥50%). Methods and Results The ‐ is a prospective longitudinal study. Participants symptomatic were recruited from 46 secondary care centers 3 Asian regions: South (India), Southeast...
The evaluation of breakthrough infection and humoral immunity responses are important outcomes for vaccination policy healthcare staff. This prospective cohort study collected blood samples at 5-time points; before primary vaccine doses, 2, 10 24 weeks after BNT162b2 from 551 HCWs, between March October 2021. We investigated the association anti-spike-1 protein receptor-binding domain (anti-S1-RBD) antibody geometric mean titre (GMT) infections. Two post-vaccination, GMT anti-S1-RBD...
Background Estimation of the economic burden heart failure (HF) through a complete evaluation is essential for improved treatment planning in future. This estimation also helps reimbursement decisions newer HF treatments. study aims to estimate cost Malaysia from Ministry Health’s perspective. Materials and methods A prevalence-based, bottom-up analysis was conducted three tertiary hospitals Malaysia. Chronic patients who received between 1 January 2016 31 December 2018 were included study....
Abstract Background This study aimed to translate and culturally adapt the Assessment of Quality Life (AQoL)-6D into Malay (Malay-AQoL-6D), assesses instrument’s acceptability, reliability, validity among Malaysians living with chronic heart failure (HF). Methods The translation cross-cultural adaptation process adhered international guidelines. Malay-AQoL-6D underwent content face assessments via expert review, pretesting healthy individuals patients conditions. Subsequent psychometric...
ObjectivesTo study the incidence of Omicron infections in Malaysia and exposures that could reduce hazard attaining infection.MethodsWe used a multicenter, prospective cohort to 482 healthcare workers vaccinated with two three doses BNT162b2 for SARS-CoV-2 infection during Omicron-dominant period Malaysia.ResultsBetween January 31 July 31, 2022, cumulative was 44.6% (95% CI 40.2-49.1%), rate 3.33 2.91-3.80) per 1000 person-days. Our found protection against significantly higher persons...
Sodium-glucose co-transporter-2 (SGLT2) inhibitors such as Empagliflozin, are increasingly recommended part of guideline-directed medical therapy (GDMT) for heart failure with reduced ejection fraction (HFrEF) in many developed nations. This recommendation is based on robust clinical evidence showing that adding Empagliflozin to GDMT improves symptoms, outcomes, functional status, and overall quality life. In Malaysia, where healthcare predominantly public heavily subsidized, the...
Abstract This study assessed the association between COVID-19 vaccines, SARS-CoV-2 infection and risk of thrombocytopenia venous thromboembolism (VTE). self-controlled case series used hospital records 1st February 2021 28th 2022 linked to national immunisation registry surveillance data in Malaysia. Conditional Poisson regression was estimate incidence rate ratios (IRR) events period (day 1–21 post-exposure) relative control with corresponding 95% confidence interval (CI) adjusted for...